Patents Assigned to JOINT CENTER FOR BIOSCIENCE
  • AB6 FAMILY DESIGNER LIGANDS OF TGF-BETA SUPERFAMILY
    Publication number: 20200325216
    Abstract: A non-naturally occurring chimeric polypeptide having an activity provided by a TGF-beta family member is disclosed. The chimeric polypeptide of an embodiment comprises two or more domains or fragments from parental TGF-beta proteins operably linked such that the resulting polypeptide is capable of modulating a pathway associated with a TGF-beta family member. In one embodiment, the pathway is a SMAD or DAXX pathway.
    Type: Application
    Filed: May 31, 2017
    Publication date: October 15, 2020
    Applicants: MOGAM INSTITUTE FOR BIOMEDICAL RESEARCH, JOINT CENTER FOR BIOSCIENCE
    Inventors: Sen Yon CHOE, Chi Hoon AHN, Ho Cheoi KIM, Hyeon Jin KIM