Patents Assigned to Josai University Corporation
  • Monoclonal antibody having immunosuppressive activity or antigen binding fragment thereof
    Patent number: 9701739
    Abstract: The present invention relates to a monoclonal antibody having excellent immunosuppressive activity or an antigen binding fragment thereof. More specifically, the present invention relates to a monoclonal antibody or an antigen binding fragment thereof, which binds to a peptide consisting an amino acid sequence represented by SSVLYGGPPSAA (SEQ ID NO: 1) or a conjugate of the peptide and a pharmaceutically acceptable carrier, the monoclonal antibody or an antigen binding fragment thereof having a higher binding affinity for core histone than for histone H1.
    Type: Grant
    Filed: August 19, 2011
    Date of Patent: July 11, 2017
    Assignee: Josai University Corporation
    Inventors: Shuji Sato, Takeshi Goto, Shigeru Goto, Toshiaki Nakano, Naoya Ohmori, Kueichen Chiang, Yayoi Shimada, Kenji Mori, Takamitsu Miyagi
  • Indole alkaloid derivatives having opioid receptor agonistic effect, and therapeutic compositions and methods relating to same
    Patent number: 8648090
    Abstract: Indole alkaloid derivatives having an opioid receptor agonistic effect, their synthesis, and therapeutic compositions containing these derivatives, and methods of treating conditions with these compounds and therapeutic compositions, are provided.
    Type: Grant
    Filed: July 16, 2012
    Date of Patent: February 11, 2014
    Assignees: National University Corporation Chiba University, Josai University Corporation
    Inventors: Hiromitsu Takayama, Mariko Kitajima, Kenjiro Matsumoto, Syunji Horie
  • MONOCLONAL ANTIBODY HAVING IMMUNOSUPPRESSIVE ACTIVITY OR ANTIGEN BINDING FRAGMENT THEREOF
    Publication number: 20140010815
    Abstract: The present invention relates to a monoclonal antibody having excellent immunosuppressive activity or an antigen binding fragment thereof. More specifically, the present invention relates to a monoclonal antibody or an antigen binding fragment thereof, which binds to a peptide consisting an amino acid sequence represented by SSVLYGGPPSAA (SEQ ID NO: 1) or a conjugate of the peptide and a pharmaceutically acceptable carrier, the monoclonal antibody or an antigen binding fragment thereof having a higher binding affinity for core histone than for histone H1.
    Type: Application
    Filed: August 19, 2011
    Publication date: January 9, 2014
    Applicant: JOSAI UNIVERSITY CORPORATION
    Inventors: Shuji Sato, Takeshi Goto, Shigeru Goto, Toshiaki Nakano, Naoya Ohmori, Kueichen Chiang, Yayoi Shimada, Kenji Mori, Takamitsu Miyagi
  • Indole Alkaloid Derivatives Having Opioid Receptor Agonistic Effect, And Therapeutic Compositions And Methods Relating To Same
    Publication number: 20120276195
    Abstract: Indole alkaloid derivatives having an opioid receptor agonistic effect, their synthesis, and therapeutic compositions containing these derivatives, and methods of treating conditions with these compounds and therapeutic compositions, are provided.
    Type: Application
    Filed: July 16, 2012
    Publication date: November 1, 2012
    Applicants: JOSAI UNIVERSITY CORPORATION, NATIONAL UNIVERSITY CORPORATION CHIBA UNIVERSITY
    Inventors: Hiromitsu Takayama, Mariko Kitajima, Kenjiro Matsumoto, Syunji Horie
  • Indole alkaloid derivatives having opioid receptor agonistic effect, and therapeutic compositions and methods relating to same
    Patent number: 8247428
    Abstract: Indole alkaloid derivatives having an opioid receptor agonistic effect, their synthesis, and therapeutic compositions containing these derivatives, and methods of treating conditions with these compounds and therapeutic compositions, are provided.
    Type: Grant
    Filed: November 7, 2008
    Date of Patent: August 21, 2012
    Assignees: National University Corporation Chiba University, Josai University Corporation
    Inventors: Hiromitsu Takayama, Mariko Kitajima, Kenjiro Matsumoto, Syunji Horie
  • DRUG PRODUCT, A METHOD OF ADMINISTRATING A VACCINE USING THE DRUG PRODUCT, AND AN APPARATUS FOR IONTOPHORESIS
    Publication number: 20100324469
    Abstract: It is an object of the present invention to provide a method and an apparatus capable of noninvasively administrating vaccine through the skin, and thereby making the immune response activate. A drug product according to the present invention is characterized in that the drug product has a support medium, an electrode formed on the support medium and protected partly by an insulating material for avoiding a direct cutaneous contact, a vaccine containing layer for containing a vaccine, wherein the vaccine is an antigen for inducing an immune suppression protein. A method of administrating a vaccine according to the present invention is characterized in that the vaccine is administrated by the iontophoresis using the drug product according to the drug product of the present invention as an electrode. An apparatus for the iontophoresis according to the present invention is characterized in that the drug product according to the present invention is used as an electrode.
    Type: Application
    Filed: October 3, 2008
    Publication date: December 23, 2010
    Applicant: JOSAI UNIVERSITY CORPORATION
    Inventors: Kenji Mori, Takamitsu Miyagi, Yayoi Shimada, Kuei-Chen Chiang, Naoya Ohmori, Takeshi Goto, Shuji Sato