Abstract: Disclosed is a catheter having a flexible tube and a sharpened needle secured to the catheter at its distal end. The catheter does not require a separate sharpened instrument to enable insertion into an anatomical passageway. The sharpened needle of the catheter remains disposed within an anatomical passageway during treatment. Also disclosed is a catheter assembly comprising the catheter and a safety inserter. The safety inserter has a blunt end and facilitates the insertion of the catheter by providing a mechanism to urge the sharpened needle of the catheter into an anatomical passageway. Also disclosed is an improved needle tip which minimizes trauma to an anatomical passageway. Also disclosed are methods of using and forming the catheter, catheter assembly and needle tip.