Patents Assigned to Josman Laboratories, Inc.
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Patent number: 6902738Abstract: Topical oral dosage forms containing bismuth compounds are described, which are useful for treating H. pylori and other bacterial infections that cause gastrointestinal disorders and halitosis, as well as for treating ocular and dermal wounds. Methods of employing topical oral dosage forms for treating bacterial infections that cause gastrointestinal disorders and halitosis, and for treating ocular and dermal wounds, are also described.Type: GrantFiled: March 19, 2002Date of Patent: June 7, 2005Assignee: Josman Laboratories, Inc.Inventors: Scott A. Gubler, Narayan K. Athanikar
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Patent number: 6616938Abstract: The invention provides a method of making a chewing gum composition containing a water soluble bulk portion, a water insoluble chewing gum base portion, a flavoring agent, and bismuth-containing compounds. The invention provides a method of making a bismuth-containing gum which when chewed multiple times per day, over the period of two weeks, is effective in reducing peptic ulcers by eradicating H. pylori. The chewing gum is also effective in eliminating forms of halitosis. The chewing gum does not have undesirable side effects, such as unpleasant taste and poor chewing characteristics.Type: GrantFiled: June 6, 2001Date of Patent: September 9, 2003Assignee: Josman Laboratories, Inc.Inventor: Narayan K. Athanikar
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Patent number: 6426085Abstract: This invention provides for a method for treatment of corneal and dermal wounds by administering bismuth compounds in topical dosage forms. Bismuth compounds cause stimulation of release of growth factors in damaged tissue to promote regeneration of epithelial cells and hence accelerate wound healing. These bismuth compounds also have good antimicrobial activity against several anaerobic bacteria involved in diaper rash exacerbation.Type: GrantFiled: May 24, 2000Date of Patent: July 30, 2002Assignee: Josman Laboratories Inc.Inventor: Narayan K. Athanikar
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Patent number: 6372784Abstract: This invention provides for a method for treatment of corneal and dermal wounds by administering bismuth compounds in topical dosage forms. Bismuth compounds cause stimulation of release of growth factors in damaged tissue to promote regeneration of epithelial cells and hence accelerate wound healing. These bismuth compounds also have good antimicrobial activity against several anaerobic bacteria involved in diaper rash exacerbation.Type: GrantFiled: March 14, 2000Date of Patent: April 16, 2002Assignee: Josman Laboratories, Inc.Inventor: Narayan K. Athanikar
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Patent number: 6322828Abstract: The present invention provides a process for preparing a chewing gum tablet, in which a chewing gum composition is cooled to a temperature at which the composition is brittle, and the composition is ground while brittle to form a fine powder. In a preferred process, the composition is cooled by mixing with a coolant, such as solid carbon dioxide, and the mixture is ground to a powder. The powder can be mixed with a pharmaceutical active ingredient capable of topical absorption in the buccal cavity or in the mucous layer of the upper or lower intestinal tract, and formed into a tablet. Preferably, the mixture of the powder, pharmaceutical active ingredient, and other additives such as coating agents, binders, additional active ingredients, and sweeteners, are granulated in a fluidized bed granulator prior to forming the mixture into a tablet. The resulting tablet provides a dosage form of the pharmaceutical active ingredient having a more accurate and uniform dose of the active ingredient.Type: GrantFiled: September 13, 1999Date of Patent: November 27, 2001Assignees: Deseret Laboratories, Inc., Josman Laboratories, Inc.Inventors: Narayan K. Athanikar, Scott A. Gubler
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Publication number: 20010036445Abstract: The invention provides a chewing gum composition containing a water soluble bulk portion, a water insoluble chewing gum base portion, a flavoring agent, and bismuth-containing compounds. The invention provides a bismuth-containing gum which when chewed multiple times per day, over the period of two weeks, is effective in reducing peptic ulcers by eradicating H. pylori. The chewing gum is also effective in eliminating forms of halitosis. The chewing gum does not have undesirable side effects, unpleasant taste and poor chewing characteristics.Type: ApplicationFiled: June 6, 2001Publication date: November 1, 2001Applicant: Josman Laboratories, Inc.Inventor: Narayan K. Athanikar
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Patent number: 6258376Abstract: The invention provides a method of making a chewing gum composition containing a water soluble bulk portion, a water insoluble chewing gum base portion, a flavoring agent, and bismuth-containing compounds. The invention provides a method of making a bismuth-containing gum which when chewed multiple times per day, over the period of two weeks, is effective in reducing peptic ulcers by eradicating H. pylori. The chewing gum is also effective in eliminating forms of halitosis. The chewing gum does not have undesirable side effects, unpleasant taste and poor chewing characteristics.Type: GrantFiled: May 4, 1998Date of Patent: July 10, 2001Assignee: Josman Laboratories, Inc.Inventor: Narayan K. Athanikar
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Patent number: 5834002Abstract: The invention provides a chewing gum composition containing a water soluble bulk portion, a water insoluble chewing gum base portion, a flavoring agent, and bismuth-containing compounds. The invention provides a bismuth-containing gum which when chewed multiple times per day, over the period of two weeks, is effective in reducing peptic ulcers by eradicating H. pylori. The chewing gum is also effective in eliminating forms of halitosis. The chewing gum does not have undesirable side effects, unpleasant taste and poor chewing characteristics.Type: GrantFiled: November 1, 1996Date of Patent: November 10, 1998Assignee: Josman Laboratories, Inc.Inventor: Narayan K. Athanikar