Abstract: A peptidomimetic agent from dextrorotatory amino acids includes vGek with Dval-gly-Dglu-Dlys as a central D-amino acid sequence, whereby gly is equal to D-glycine, which is equal to L-glycine. Pharmaceutical agents for use in the treatment of neurodegenerative diseases, in particular Alzheimer's disease, Parkinson's disease, Lewy Body dementia, Creutzfeldt-Jakob disease, as well as Huntington's Chorea disease, multi-system atrophy as well as disorders similar to these neurodegenerative diseases that contain at least one peptidomimetic agent from dextrorotatory amino acids are also included.
Type:
Grant
Filed:
April 14, 2008
Date of Patent:
March 29, 2011
Assignee:
JSW-Research Forschungslabor GmbH
Inventors:
Manfred Windisch, Birgit Hutter-Paier, Robert Wronski