Abstract: Novel polyadenylic acid (5') derivatives with 2'-0-(3-fluoro-4,6-dinitrophenyl) groups and/or 2'-0-(2,4-dinitrophenyl) groups have been synthesized and discovered to act as mutation-insensitive and function-specific inhibitors of viral reverse transcriptase.
Type:
Grant
Filed:
February 23, 1994
Date of Patent:
March 5, 1996
Assignee:
Jui H. Wang
Inventors:
Jui H. Wang, Insug Kang, Mohammed H. Rahman