Patents Assigned to Julius-Maxmilians-Universitat Wurzburg
  • Monoclonal antibodies to growth and differentiation factor 15 (GDF-15), and uses thereof for treating cancer cachexia and cancer
    Patent number: 11634482
    Abstract: The present invention relates to monoclonal anti-human-GDF-15 antibodies. The antibodies include chimeric anti-bodies and humanized antibodies. The invention also relates to monoclonal anti-human-GDF-15 antibodies including murine anti-bodies, chimeric antibodies and humanized antibodies for use in methods for the treatment of cancer cachexia and also for the treatment of cancer. The invention also provides pharmaceutical compositions, kits, methods and uses and cell lines capable of producing the monoclonal antibodies of the invention.
    Type: Grant
    Filed: February 19, 2020
    Date of Patent: April 25, 2023
    Assignee: Julius-Maxmilians-Universitat Wurzburg
    Inventors: Jörg Wischhusen, Markus Junker, Tina Schäfer, Dirk Pühringer