Patents Assigned to Justus-Liebig Universitat Giessen
  • Publication number: 20120171658
    Abstract: The present invention relates to a device and a procedure for the withdrawal, manufacture, storage and transportation of blood products in the widest sense, in particular a closed blood removal, processing and storages system, as well as a system suitable for the administration of medicinal products which are obtained from blood or blood products, and a corresponding procedure for the legally conformant and GMP-compliant preparation, manufacture, storage and transportation of blood products or blood components or blood constituents or blood preparations (within the meaning of the Medical Products Act AMG). The present invention in particular allows the manufacture, storage, transportation and administration of completely aliquoted autologous serum eye drops for direct application to the patient or other drugs manufactured from blood or blood products without the need for clean room laboratories.
    Type: Application
    Filed: May 27, 2010
    Publication date: July 5, 2012
    Applicant: JUSTUS-LIEBIG-UNIVERSITÄT GIESSEN
    Inventors: Gregor Bein, Holger Hackstein, Joachim Misterek
  • Publication number: 20120148493
    Abstract: The invention relates to composite materials comprising polymer nanofibers and polymer nanoparticles, wherein at least one of the two polymer materials is loaded with a substance selected from therapeutic and diagnostic agents. Fibers and nanoparticles can comprise identical or different polymers; the polymer materials are, however, biocompatible in every case. Therapeutic and diagnostic agents can be hydrophilic or lipophilic and the two polymer materials likewise. The at least one polymer material and the substance with which said material is loaded are either both hydrophilic or both lipophilic. The polymer nanoparticles of the composite materials have a diameter of 10 nm to 600 nm. The polymer fibers have diameters of 10 nm to 50 ?m and lengths of 1 ?m to several meters. The invention further relates to a method for producing said composite materials.
    Type: Application
    Filed: March 16, 2010
    Publication date: June 14, 2012
    Applicant: Justus-Liebig-Universitat Giessen
    Inventors: Thomas Schmehl, Juliane Nguyen, Moritz Beck-Broichsitter, Tobias Gessler, Thomas Kissel, Marcel Thieme
  • Publication number: 20120129800
    Abstract: The present invention concerns an agent for prevention and treatment of pityriasis. The agent according to the present invention comprises at least one transaminase inhibitor effectively inhibiting the transamination process which is of pathogenetic relevance for the disease, prevents a recurrence of the disease and which protects the human skin flora. Upon release into the environment, no resistances are induced in other fungi.
    Type: Application
    Filed: January 14, 2010
    Publication date: May 24, 2012
    Applicant: Justus-Liebig-Universitat Giessen
    Inventor: Peter Mayser
  • Patent number: 8158353
    Abstract: The present invention concerns a method for the species-specific and quantitative detection of CNS tissue in meat and meat products of the ruminant species bovine, ovine and caprine or porcine by a real-time PCR method, using glial fibrillary acidic protein (GFAP) messenger (m)-RNA. The method is very reliable and can be easily conducted even in heat-treated samples.
    Type: Grant
    Filed: December 13, 2004
    Date of Patent: April 17, 2012
    Assignee: Justus-Liebig-Universitat Giessen
    Inventors: Michael Bulte, Holger Schonenbrucher, Amir Abdulmawjood
  • Patent number: 8124588
    Abstract: The present invention relates to recombinant chimeric proteins comprising a surfactant protein precursor N-terminally fused to a plasminogen activator or comprising a mature surfactant protein N-terminally or C-terminally fused to a plasminogen activator. The invention is also directed to the corresponding nucleic acid molecules encoding such fusion proteins as well as to a method for their production. The invention further refers to a pharmaceutical composition comprising such a fusion protein and to pharmacological uses of an inventive fusion protein for the prevention and/or treatment of inflammatory and interstitial lung diseases.
    Type: Grant
    Filed: December 18, 2003
    Date of Patent: February 28, 2012
    Assignee: Justus Liebig Universität Giessen
    Inventors: Werner Seeger, Andreas Günther, Clemens Ruppert, Philipp Markart, Viktor Magdolen, Timothy E. Weaver
  • Publication number: 20110300251
    Abstract: Carriers for the production and targeted and/or delayed release, particularly of agricultural active substances, as well as a method for the output and a device for the production of such carriers in a loaded or unloaded state are proposed. The method and the device use the technology of electrospinning.
    Type: Application
    Filed: August 8, 2011
    Publication date: December 8, 2011
    Applicants: Justus-Liebig Universitat Giessen, Philipps-Universitat Marburg
    Inventors: Andreas GREINER, Hans E. Hummel, Joachim H. Wendorff, Mathias Becker, Roland Dersch
  • Publication number: 20110300383
    Abstract: The invention relates to supports consisting of nanoscalar polymer fibres, polymer tubes or hollow fibres for the application and targeted and/or delayed release of ingredients, in particular, agricultural active ingredients. The invention also relates to a method and a device for the production of supports of this type in a charged or empty state. The method and device use electrospinning technology.
    Type: Application
    Filed: August 8, 2011
    Publication date: December 8, 2011
    Applicants: Justus-Liebig Universitat Giessen, Philipps-Universitat Marburg
    Inventors: Andreas GREINER, Hans E. Hummel, Joachim H. Wendorff, Mathias Becker, Roland Dersch
  • Publication number: 20110293846
    Abstract: The invention relates to supports consisting of nanoscalar polymer fibres, polymer tubes or hollow fibres for the application and targeted and/or delayed release of ingredients, in particular, agricultural active ingredients. The invention also relates to a method and a device for the production of supports of this type in a charged or empty state. The method and device use electrospinning technology.
    Type: Application
    Filed: August 8, 2011
    Publication date: December 1, 2011
    Applicants: Justus-Liebig Universitat Giessen, Philipps-Universitat Marburg
    Inventors: Andreas GREINER, Hans E. Hummel, Joachim H. Wendorff, Mathias Becker, Roland Dersch
  • Publication number: 20110269157
    Abstract: The present invention discloses an immunological test for the detection and specific determination of autoantibodies against testicular antigens which are associated with inflammation-related fertility disorders of male mammals in a biological sample of a male mammal, in particular the detection of testicular ER-60 autoantibodies and/or transferrin autoantibodies. The immunological test is utilized to detect the presence of immunologically-caused and infection-related infertility in male mammals, particularly in humans.
    Type: Application
    Filed: October 22, 2009
    Publication date: November 3, 2011
    Applicant: Justus-Liebig-Universitat Giessen
    Inventors: Andreas Meinhardt, Monika Fijak
  • Patent number: 8017061
    Abstract: The invention relates to supports consisting of nanoscalar polymer fibres, polymer tubes or hollow fibres for the application and targeted and/or delayed release of ingredients, in particular, agricultural active ingredients. The invention also relates to a method and a device for the production of supports of this type in a charged or empty state. The method and device use electrospinning technology.
    Type: Grant
    Filed: May 30, 2005
    Date of Patent: September 13, 2011
    Assignees: Philipps-Universitat Marburg, Justus-Liebig Universitat Giessen
    Inventors: Andreas Greiner, Hans E. Hummel, Joachim H. Wendorff, Mathias Becker, Roland Dersch
  • Publication number: 20110124912
    Abstract: The invention at hand describes functionalized diols of diamondoids, in which one of the two hydroxy groups is masked by a protective group, as well as methods for producing these functionalized diols. The protective group is a group —CHR1R2, wherein R1 and R2 stand for alkyl groups and the protective group comprises at least one halogen atom. The monoethers of the diamondoid diols according to the present invention are produced by reacting the diamondoid diol with a halogenated alcohol CHOHR1R2 in the presence of a catalyst acid. The monoetherified diols allow for the targeted production of derivatives of diamondoids, for example, of the corresponding aminoalcohols and aminocarboxylic acids. For that purpose, the diamondoid monoether is reacted in a first step with a halogen nitrile in a Ritter reaction to the corresponding monoether amide.
    Type: Application
    Filed: June 2, 2009
    Publication date: May 26, 2011
    Applicant: JUSTUS-LIEBIG-UNIVERSITAT GIESSEN
    Inventors: Peter R. Schreiner, Hartmut Schwertfeger