Abstract: A method of stabilizing R-?-lipoic acid includes combining R-?-lipoic acid with nicotinamide in a weight ratio between about 10:4 to about 10:8. A composition for treating oxidative stress includes R-?-lipoic acid and nicotinamide in a weight ratio of between about 10:4 and about 10:8.

Abstract: Supplemented food formulations are disclosed. A gelatin has a composition comprising an effective amount of an antioxidant having anti-aging properties, an effective amount of a carnitine having anti-aging properties, a carbohydrate source for calories, an effective amount of at least one B vitamin, and flavors.

Abstract: Disclosed herein are compositions to meet the needs of aged pets and other animals. A pet food formulated for senior pets provides &agr;-lipoic acid at about 0.15 to 50 mg/kg body weight/day, carnitine at about 0.5 to 100 mg/kg/day, and optionally coenzyme Q at about 0.01 mg/kg/day and/or creatine at about 15 mg to about 1 g/kg/day. A pet treat for senior pets provides &agr;-lipoic acid at about 0.15 to 50 mg/kg body weight/day, carnitine at about 0.5 to 100 mg/kg/day, and optionally coenzyme Q at about 0.01 mg/kg/day and/or creatine at about 15 mg to about 1 g/kg/day. A pet supplement for mature pets offers &agr;-lipoic acid at about 0.15 to 50 mg/kg body weight/day, carnitine at about 0.5 to 100 mg/kg/day, and optionally coenzyme Q at about 0.01 mg/kg/day and/or creatine at about 15 mg to about 1 g/kg/day.

Abstract: Disclosed herein are compositions to meet the needs of individuals, including humans and pets. Nutritional beverages, powders to make the same, a pudding and a nutritional bar are disclosed whose compositions include the R-&agr;-lipoic acid in the amount of 0.12 grams to 1.5 grams and L-carnitine in the amount of 0.12 grams to 3 grams in addition to the usual composition. Optionally, effective amounts of coenzyme Q and/or creatine also are added. These additional components fight age-related declines in mitochondrial function which result in less energy and other signs of aging.

Abstract: Disclosed herein are methods to treat cognition disorders, particularly those associated with aging. The method comprises administering a combination of a carnitine and an oxidant. Preferably the oxidant is thioctic acid. Preferably 0.12 grams to 3 grams of carnitine (particularly ALC) and 0.12 and 1.5 grams of R-&agr;-lipoic acid are administered. Optionally, coenzyme Q and/or creatine also are administered. Preferably 10 mg to 500 mg/day of coenzyme Q10 and 1 to 30 grams/day of creatine are administered. The same method can be used to treat cognition deficits associated with carbon monoxide poisoning, mild traumatic brain injury, Type 2 diabetes mellitus, obsessive-compulsive disorder, environmental toxin exposure, and other conditions.