Patents Assigned to JUVIC INC.
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Patent number: 12233229Abstract: The present invention relates to a perforated plate microstructure module, and more particularly, to a perforated plate microstructure module which can be used to deliver a drug into the skin.Type: GrantFiled: February 23, 2021Date of Patent: February 25, 2025Assignees: INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY, JUVIC INC.Inventors: Hyung Il Jung, Hui Suk Yang, Hyeon Jun Kim
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Patent number: 12048771Abstract: A multifunctional microstructure patch is provided. The multifunctional microstructure patch, according to one embodiment of the present invention, comprises: a base layer having an opening part formed in the center thereof; a plurality of microstructures formed on one surface of the base layer and comprising a first drug; and a cover layer detachably bonded on the other surface of the base layer along the periphery of the opening part, and formed so as to cover the opening part.Type: GrantFiled: October 4, 2019Date of Patent: July 30, 2024Assignees: INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY, JUVIC INCInventors: Hyungil Jung, Huisuk Yang
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Publication number: 20230414746Abstract: The present invention relates to a microneedle including an influenza vaccine and particularly a soluble microneedle including an influenza vaccine, and more specifically to a microneedle including an influenza vaccine and an influenza vaccine patch including the same that can increase the stability of the influenza vaccine and expect a higher immune effect by including a water-soluble polymer and an additive at a specific ratio, and when the microneedle including the influenza vaccine of the present invention is used, not only the stability of the vaccine is increased, but also the skin penetration and drug delivery effect are remarkably excellent.Type: ApplicationFiled: December 22, 2022Publication date: December 28, 2023Applicants: UIF (University Industry Foundation), Yonsei University, JUVIC INC.Inventors: Hyungil JUNG, Huisuk YANG, Geonwoo KANG
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Patent number: 11382841Abstract: The present invention relates to a method of manufacturing a microstructure, including: (a) forming a solid on a substrate; (b) fluidizing the solid by adding a solvent thereto; and (c) shaping the fluidized solid, and a microstructure manufactured using the method.Type: GrantFiled: July 13, 2016Date of Patent: July 12, 2022Assignee: JUVIC INC.Inventors: Hyung Il Jung, Hui Suk Yang
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Patent number: 11104044Abstract: Provided is a rotating assembly. The rotating assembly is for forming a microstructure, and comprises: a rotating body rotatable about a rotary shaft; a first support member installed on the rotating body so as to be spaced apart from the rotational shaft and having a predetermined viscous composition disposed on an outer surface thereof; and a fluid communicating portion for communicating the inside and the outside of the rotating body, wherein when the rotating body rotates, the viscous composition is pulled in a radially outward direction of the rotary shaft, and the pulled viscous composition is cured through the fluid communicating portion, thereby forming a microstructure.Type: GrantFiled: April 12, 2017Date of Patent: August 31, 2021Assignee: JUVIC INC.Inventors: Hyung Il Jung, Hui Suk Yang
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Publication number: 20210170154Abstract: The present invention relates to a perforated plate microstructure module, and more particularly, to a perforated plate microstructure module which can be used to deliver a drug into the skin.Type: ApplicationFiled: February 23, 2021Publication date: June 10, 2021Applicants: INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY, JUVIC INC.Inventors: Hyung Il JUNG, Hui Suk YANG, Hyeon Jun KIM
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Patent number: 10737081Abstract: The present invention relates to a painless and patchless shooting microstructure, and a microstructure shooting device. According to the present invention, it is possible to inject a microstructure into the skin within the time of less than one second, and the inconvenience of waiting for the decomposition of a microstructure and removing a patch are completely overcome. A patch-type conventional technology has a problem wherein it is difficult to be applied to a region having hair, but the present invention completely overcomes this problem. According to the present invention, it is possible to precisely control the permeation depth of a microstructure into the skin by controlling discharge power.Type: GrantFiled: June 17, 2014Date of Patent: August 11, 2020Assignee: JUVIC INC.Inventors: Hyung Il Jung, Shayan Fakhraeli Lahiji
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Patent number: 10537518Abstract: A viscous composition for transdermal drug delivery, a method of preparing the same, and a microstructure device prepared using the viscous composition are provided. Here, the viscous composition includes colloidal particles formed of a combination of a drug and a biodegradable polymer, and the biodegradable polymer includes a first amphiphilic polymer. The use of a solvent can be minimized to homogenize the drug in the biodegradable polymer including the first amphiphilic polymer, thereby forming colloidal particles. Therefore, since a separate solvent cannot be used, the microstructure device is expected to be a transdermal drug delivery system which is safe, efficient or useful for drugs which do not include a proper solvent, show poor bioavailability or have a high molecular weight.Type: GrantFiled: March 28, 2016Date of Patent: January 21, 2020Assignee: Juvic Inc.Inventors: Hyung Il Jung, Dangol Manita
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Patent number: 10441545Abstract: The present invention relates to a microcontainer microstructure including a microcontainer film structure having a sharp tip portion and a method of manufacturing the same.Type: GrantFiled: December 16, 2015Date of Patent: October 15, 2019Assignee: JUVIC INC.Inventors: Hyung Il Jung, Su Yong Kim, Hui Suk Yang
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Patent number: 10245423Abstract: The present invention relates to a method for manufacturing a microstructure, the method comprising the steps of: (a) preparing a viscous composition on a lower substrate; and (b) applying centrifugal force to the viscous composition to induce extension of the viscous composition, thereby manufacturing a microstructure. According to the present invention, (i) a microstructure having a micro-unit diameter and sufficient effective length and hardness is provided; (ii) any process that may destroy activation of a drug or cosmetic component, such as high-temperature treatment, organic solvent treatment, etc., is avoided; (iii) loss resulting from contact and separation is reduced; (iv) the limitation of aspect ratio of the manufactured microstructure is overcome; (v) the limitation of yield resulting from flatness is overcome; and (vi) microstructures of various shapes can be manufactured.Type: GrantFiled: May 2, 2014Date of Patent: April 2, 2019Assignee: JUVIC INC.Inventors: Hyung Il Jung, Hui Suk Yang, Su Yong Kim
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Publication number: 20180200157Abstract: The present invention relates to a method of manufacturing a microstructure, including: (a) forming a solid on a substrate; (b) fluidizing the solid by adding a solvent thereto; and (c) shaping the fluidized solid, and a microstructure manufactured using the method.Type: ApplicationFiled: July 13, 2016Publication date: July 19, 2018Applicant: JUVIC INC.Inventors: Hyung Il JUNG, Hui Suk YANG
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Patent number: 9974936Abstract: The present invention is directed to a method for manufacturing a microstructure, the method comprising: (a) placing a viscous composition on a substrate; and (b) applying negative pressure to the viscous composition to induce an extension of the viscous composition, thereby forming a microstructure, and a microstructure manufactured therefor. According to the present invention, a microstructure can be formed without performing a heat treatment by applying a negative pressure. Consequently, it is possible to mount on a microstructure various materials that are sensitive to heat and easily damaged or degenerated. According to the present invention, a microstructure can be manufactured in a non-contacting manner, that is, without being contacted with conventionally used another structure such as a mold or filler.Type: GrantFiled: February 20, 2014Date of Patent: May 22, 2018Assignee: JUVIC INC.Inventors: Hyung Il Jung, Hui Suk Yang
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Patent number: 9943674Abstract: Disclosed are a microstructure-based drug delivery system comprising a microporous structure and a method for manufacturing the same, and more specifically, a detachable microstructure-based drug delivery system using a microporous structure layer and a method for manufacturing the same, thereby skipping a drying step which is essential for the manufacturing process of the existing biodegradable microneedle, and solving the problem in that the hardness of the microneedle is reduced when the microneedle contains drugs, failing to penetrate the skin. Here, the microstructure is implantable in the body through the insertion into the body and detachment from the microporous structure, and the detachable microstructure can be applied to wrinkled (skin movement) and corrugated parts through a detachment function thereof.Type: GrantFiled: February 13, 2015Date of Patent: April 17, 2018Assignee: JUVIC INC.Inventors: Hyung Il Jung, Hui Suk Yang
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Publication number: 20170285056Abstract: The present invention relates to a device for collecting body fluids including (a) a fluid receiving part including a fluid receiving space in which an internal low pressure less than an external atmospheric pressure is formed; (b) a fluid collection part including a hollow microstructure connected to form an open system with the fluid receiving space of the fluid receiving part; and (c) a microstructure hollow barrier for blocking the hollow of the microstructure to maintain the internal low pressure formed in the fluid receiving means.Type: ApplicationFiled: September 18, 2015Publication date: October 5, 2017Applicant: JUVIC INC.Inventors: Hyung II JUNG, Chengguo LI
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Publication number: 20170105928Abstract: A viscous composition for transdermal drug delivery, a method of preparing the same, and a microstructure device prepared using the viscous composition are provided. Here, the viscous composition includes colloidal particles formed of a combination of a drug and a biodegradable polymer, and the biodegradable polymer includes a first amphiphilic polymer. The use of a solvent can be minimized to homogenize the drug in the biodegradable polymer including the first amphiphilic polymer, thereby forming colloidal particles. Therefore, since a separate solvent cannot be used, the microstructure device is expected to be a transdermal drug delivery system which is safe, efficient or useful for drugs which do not include a proper solvent, show poor bioavailability or have a high molecular weight.Type: ApplicationFiled: March 28, 2016Publication date: April 20, 2017Applicant: JUVIC INC.Inventors: Hyung IL JUNG, Dangol MANITA