Abstract: This application is directed to chemokine-immunoglobulin fusion polypeptides and chemokine-polymer conjugates. The fusion polypeptides and conjugates can be used for treating chemokine receptor-mediated disorders and modulating inflammation, inflammatory cell motility, cancer cell motility, or cancer cell survival.
Abstract: Milled nanoparticles comprising a biologically active agent, at least one biopolymer and a coating containing at least one coating which is a polymer or ligand are produced using milling and coating techniques which have not previously been used for these applications.
Type:
Grant
Filed:
November 10, 2010
Date of Patent:
February 24, 2015
Assignee:
Jyant Technologies, Inc.
Inventors:
James W. Lillard, Rajesh Singh, Shailesh Singh