Abstract: A detection and response system includes a central server having at least one continuously trained neural network and at least one remote system connected to the central server. The at least one remote system includes a first sensor configured to provide an analyzable output corresponding to sensed information to an instanced copy of the continuously trained neural network, and a response system configured to generate a response to the instanced copy of the continuously trained neural network providing a positive detection. A training module is stored on the central server and is configured to update one of the continuously trained neural network and the instanced copy of the continuously trained neural network in response to receiving a data set including the positive detection.