Patents Assigned to Kaist
-
Patent number: 9777261Abstract: The present application describes an isolated nucleic acid molecule encoding a polypeptide capable of synchronously binding VEGF polypeptide and placenta growth factor (PIGF) polypeptide comprising a nucleotide sequence encoding a VEGFR1 component.Type: GrantFiled: June 15, 2015Date of Patent: October 3, 2017Assignee: Korea Advanced Institute of Science and Technology (KAIST)Inventors: Ho Min Kim, Jung-Eun Lee, Chan Kim, Gou Young Koh, Gyun Min Lee
-
Patent number: 9703395Abstract: Disclosed herein is an accurate and efficient, yet non-obtrusive system and method (using same) for detecting interpersonal touch, such as a high-five, which is prevalent in people's daily lives, so as to promote everyday interactions at diverse settings. Based on ubiquitous computing technology, one embodiment of the system for detecting interpersonal touch comprises a pre-motion filter for filtering a pre-motion prior to the interpersonal touch, a sensor for sensing electrical properties of skin, an evaluator for analyzing and determining the interpersonal touch based on the pre-motion and the electrical properties of skin, and a communicator for communicating information analyzed by the evaluator. Other embodiments are described and shown.Type: GrantFiled: March 24, 2015Date of Patent: July 11, 2017Assignee: KOREA ADVANCED INSTITUTE OF SCIENCE & TECHNOLOGY (KAIST)Inventors: Junehwa Song, Yuhwan Kim, Seungchul Lee, Inseok Hwang, Hyunho Ro, Youngki Lee, Miri Moon
-
Patent number: 9644209Abstract: The present invention relates to a multi-conjugate of small interfering RNA (siRNA) and a preparing method of the same, more precisely a multi-conjugate of siRNA prepared by direct binding of double stranded sense/antisense siRNA monomers or indirect covalent bonding mediated by a cross-linking agent or a polymer, and a preparing method of the same. The preparing method of a siRNA multi-conjugate of the present invention is characterized by simple and efficient reaction and thereby the prepared siRNA multi-conjugate of the present invention has high molecular weight multiple times the conventional siRNA, so that it has high negative charge density, suggesting that it has excellent ionic interaction with a cationic gene carrier and high gene delivery efficiency.Type: GrantFiled: June 23, 2014Date of Patent: May 9, 2017Assignee: Kaist IP Co. Ltd.Inventors: Tae Gwan Park, Hye Jung Mok, Soo Hyeon Lee
-
Patent number: 9616085Abstract: The present invention relates to siRNA hydrogel and a method for manufacturing the same, and more particularly, to siRNA hydrogel for targeted gene silencing, which is nano-structured for targeted gene silencing, and a method for manufacturing the same.Type: GrantFiled: November 3, 2011Date of Patent: April 11, 2017Assignee: KAIST IP CO., LTD.Inventors: Cheol Am Hong, Yoon Sung Nam, Haeshin Lee
-
Patent number: 9555796Abstract: A hybrid vehicle includes: an engine; a driving motor/generator connected to an output shaft of the engine; a connection unit disposed between the engine and the driving motor/generator to separate the engine from the driving motor/generator when the engine is stopped and to connect the engine to the driving motor/generator when the engine is operated; a manual transmission connected to the driving motor/generator, for directly varying gear ratio without using an engine clutch according to a driving speed and a torque generated by the driving motor/generator and/or the engine; a position sensor for detecting a position of a manual gearshift lever; and a central control unit connected to the engine, the driving motor/generator, the connection unit, and the manual transmission.Type: GrantFiled: June 12, 2014Date of Patent: January 31, 2017Assignee: KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KAIST)Inventors: Yong San Yoon, Sei Bum Choi, Kyung Soo Kim, Sun Je Kim, Chi Woong Song, Hee Woon Son
-
Patent number: 9375751Abstract: A method for manufacturing an inorganic-nano structure composite, a method for manufacturing a cabon nanotube composite by using the same, and a carbon nanotube composite manufactured by the same are provided. The method for manufacturing the inorganic-nano structure composite comprises a step of doping pentavalent elements on the nanostructure; and a step of growing the inorganic material from the doping points of the pentavalent elements by dipping the nanostructure on which the pentavalent elements are doped into a precursor solution of the inorganic material, and according to the present invention the pentavalent elements such as nitrogen are doped on the nanostructure and is utilized as the crystallization point of the inorganic material, instead of forming the separate coating layer to the organic-based nanostructure, or binding the binding group to the surface.Type: GrantFiled: November 29, 2011Date of Patent: June 28, 2016Assignee: KAIST (Korea Advanced Institute of Science and Technology)Inventors: Sang-Ouk Kim, Won-jun Lee, Duck-hyun Lee, Jin-ah Lee
-
Patent number: 9255269Abstract: The present invention relates to a multi-conjugate of small interfering RNA (siRNA) and a preparing method of the same, more precisely a multi-conjugate of siRNA prepared by direct binding of double stranded sense/antisense siRNA monomers or indirect covalent bonding mediated by a cross-linking agent or a polymer, and a preparing method of the same. The preparing method of a siRNA multi-conjugate of the present invention is characterized by simple and efficient reaction and thereby the prepared siRNA multi-conjugate of the present invention has high molecular weight multiple times the conventional siRNA, so that it has high negative charge density, suggesting that it has excellent ionic interaction with a cationic gene carrier and high gene delivery efficiency.Type: GrantFiled: October 8, 2013Date of Patent: February 9, 2016Assignee: KAIST IP CO. LTD.Inventors: Tae Gwan Park, Hye Jung Mok, Soo Hyeon Lee
-
Patent number: 9229079Abstract: A parallel imaging (PI) method has been frequently used as a method for shortening an image acquisition time in the MRI field. The PI technique is a method for acquiring data using multi-channel coils, that is, several coils, when acquiring the data in MRI. According to this technique, data, the amount of which is smaller than that when the data is obtained using only one coil, is acquired, and then an image is obtained using coil information. According to an embodiment, a new image reconstruction method is proposed which adopts an expectation maximization (EM) technique that is different from the existing GRAPPA or SENSE technique when an image is obtained using PI data acquired through the radial trajectory.Type: GrantFiled: December 13, 2012Date of Patent: January 5, 2016Assignee: KAIST (Korea Advanced Institute of Science and Technology)Inventors: HyunWook Park, Joonsung Choi
-
Publication number: 20150368617Abstract: The present application discloses a method of promoting differentiation and expansion of endothelial cells (EC) and cardiomyocytes from a pluripotent cell, which includes contacting the pluripotent cell with a Rho-associated protein kinase (ROCK) suppressor.Type: ApplicationFiled: May 7, 2014Publication date: December 24, 2015Applicant: Korea Advanced Institute of Science and Technology (KAIST)Inventors: Gou Young KOH, Hyung Joon Joo, Dong Kyu Choi, Jin-Sung Park, Sung Woo Cho
-
Patent number: 9207175Abstract: A condensing-type portable fluorescence detection system which detects antigens using fluorescence includes: a light source generating light to excite a fluorescent substance; a first filter selecting a proper wavelength range from the light generated from the light source; a spherical mirror including two hemispherical mirrors having different curvature radiuses and connected to each other, and condensing the light excited and emitted from the light source; a second filter selecting a proper wavelength range of the light condensed by the spherical mirror; and a photodetector detecting fluorescence from the light condensed by the spherical mirror and passing through the second filter.Type: GrantFiled: December 14, 2012Date of Patent: December 8, 2015Assignee: KAIST (Korea Advanced Institute Of Science And Technology)Inventors: Kyoungsik Yu, Byounghun Park, Kyungmook Kwon
-
Patent number: 9170350Abstract: The present invention provides a lens having broadband anti-reflective nanostructures formed using nano-island masks and a method for making the same, in which nanostructures having a size and period equal to or smaller than the light wavelength are formed on the surface of a lens to obtain a lens having decreased reflectance, increased transmittance and high efficiency. The lens having broadband anti-reflective nanostructures formed using nano-island masks comprises: a lens having a planar shape or a predetermined curvature; and anti-reflective nanostructures formed on one surface of the lens using nano-island masks, in which the horizontal and vertical cross-sections of the anti-reflective nanostructures have a size equal to or smaller than the light wavelength.Type: GrantFiled: November 26, 2012Date of Patent: October 27, 2015Assignee: KAIST (Korea Advanced Institute of Science and Technology)Inventors: Ki-Hun Jeong, Hyukjin Jung
-
Patent number: 9140122Abstract: A tunnel excavation technique using a water jet. A water jet system includes a moving unit movable back and forth with respect to an area to be blasted for tunnel excavation, an articulated robot arm mounted on the moving unit, a water jet nozzle which ejects high-pressure water and an abrasive toward an area to be excavated, and a control unit which controls the moving unit, the articulated robot arm and the water jet nozzle. A free face having a predetermined depth is formed of the area to be excavated in the direction in which the tunnel is to be excavated using the water jet system. Since the blasting is performed after the free face is formed, blast vibration can be effectively restricted.Type: GrantFiled: October 4, 2011Date of Patent: September 22, 2015Assignee: KAIST (KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY)Inventors: Gye-Chun Cho, Tae-Min Oh
-
Patent number: 9113586Abstract: Disclosed is a device for bonding a flexible PCB (Printed Circuit Board) to a camera module, the device according to an exemplary embodiment of the present disclosure comprising a thermo-compression unit configured to bond the camera module to the flexible PCB using an conductive film by applying heat and pressure to the conductive film between the camera module and the flexible PCB, an ultrasonic wave bonding unit configured to directly transmit ultrasonic wave vibration energy to the camera module to remove an oxide film on connection particles intrinsically formed inside the conducive film, and a controller configured to activate the ultrasonic wave bonding unit when a temperature of the conductive film rises to a predetermined temperature.Type: GrantFiled: February 22, 2013Date of Patent: August 18, 2015Assignees: LG INNOTEK CO., LTD., KAIST (KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY)Inventors: Jae Chun Lee, Kyuong-wook Paik, Yoo Sun Kim, Kiwon Lee
-
Patent number: 9065396Abstract: Provided is a method in which a Digital Pre-Distorter (DPD) performs digital pre-distortion on a received In-phase (I) signal, a received Quadrature-phase (Q) signal, a feedback I signal, and a feedback Q signal; a mixer mixes a signal output from the DPD with a frequency signal output from an oscillator; each of n phase shifters phase-shifts a signal output from the mixer according to a preset beamforming pattern; each of n Power Amplifiers (PAs) amplifies a signal output from an associated phase shifter according to a gain, the PAs connected to the associated phase shifter on a one-to-one basis; each of n envelope detectors detects an envelope signal from a signal output from an associated PA, the envelope detector connected to the associated PA on a one-to-one basis; and a control unit determines whether the n PAs operate normally, using the envelope signals output from the n envelope detectors.Type: GrantFiled: December 26, 2012Date of Patent: June 23, 2015Assignees: Samsung Electronics Co., Ltd., Korea Advanced Institute of Science and Technology (KAIST)Inventors: Mi-Hyun Son, Yong-Hoon Kim, Byung-Tae Yoon, Jong-Wook Zeong, Dong-Geun Lee, Jae-Hun Lee, Song-Cheol Hong
-
Publication number: 20150030203Abstract: Provided are a fire detecting apparatus and a method thereof for detecting a fire, the method includes operations of extracting a feature of at least one object in an input image by using a value of a brightness difference between pixels of the input image or by using an RGB value of the input image; converting the extracted feature of the at least one object into an N dimensional feature; and performing Support Vector Machine (SVM) machine learning on the N dimensional feature of the at least one object.Type: ApplicationFiled: May 28, 2014Publication date: January 29, 2015Applicants: SAMSUNG TECHWIN CO., LTD., Korea Advanced Institute of Science and Technology (KAIST)Inventors: Ji Ho KIM, Hyun Nam LEE, Soon Min BAE, Soon Min HWANG, Jong Won CHOI, Joon Young LEE, Tae Hyun OH, In So KWEON
-
Patent number: 8934740Abstract: Disclosed herein is a fiber optic sensor using a transmissive grating panel and a mirror, in which displacement resulting from a temperature change in the external environment or a behavioral change in an object to be measured is measured using a transmissive grating panel, a reflection mirror and an optical fiber, and then enables various measurements to be taken of the temperature change in the external environment and the behavioral change (displacement, pressure, vibration or acceleration, etc.) in the object on the basis of the measured displacement.Type: GrantFiled: May 14, 2012Date of Patent: January 13, 2015Assignee: Korea Advanced Institute of Science and Technology (KAIST)Inventors: Chun-Gon Kim, Yeon-Gwan Lee, Byeong-Wook Jang, Jin-Hyuk Kim, Yoon-Young Kim
-
Patent number: 8927232Abstract: The present application describes an isolated nucleic acid molecule encoding a polypeptide capable of synchronously binding VEGF polypeptide and TNF polypeptide comprising: (a) a nucleotide sequence encoding a TNFR2 component and VEGFR1 component operatively linked to (b) a nucleotide sequence encoding a multimerizing component, wherein the TNFR2 component consists essentially of a nucleotide sequence encoding the amino acid sequences of cystein rich domain 1, cystein rich domain 2, cystein rich domain 3, and cystein rich domain 4 of the extracellular domain of TNFR2, and wherein the VEGFR1 component consists essentially of a nucleotide sequence encoding the amino acid sequences of Ig-like domain 2 of the extracellular domain of VEGFR1.Type: GrantFiled: December 11, 2009Date of Patent: January 6, 2015Assignee: Korea Advanced Institute of Science and Technology (KAIST)Inventors: Keehoon Jung, Young Jun Koh, Gyun Min Lee, Sun Chang Kim, Gou Young Koh
-
Publication number: 20140370079Abstract: The present application describes a method of inhibiting tumor growth including contacting the tumor with a compound that inhibits activity of RhoJ protein.Type: ApplicationFiled: May 6, 2014Publication date: December 18, 2014Applicant: Korea Advanced Institute of Science and Technology (KAIST)Inventors: Gou Young KOH, Chan Kim, Hanseul Yang, Won Do Heo, Injune Kim, Sangyong Jon, Akiyoshi Uemura
-
Patent number: 8906624Abstract: Provided are a rotational PCR apparatus, a PCR chip for the same and a rotational PCR method using the same. The disclosed rotational PCR apparatus includes: a PCR chip where PCR is performed; a rotating means connected to the PCR chip and rotating the PCR chip; and a temperature zone forming means spaced apart from the PCR chip, capable of applying thermal energy to the PCR chip and allowing the rotating PCR chip to pass through different temperature zones. The rotational PCR apparatus and method allow performance of PCR with wanted temperature condition and cycles by rotating the chip containing the target substance. Accordingly, a high-efficiency PCR process may be accomplished at low cost. Further, since the target substance can be effectively separated and purified utilizing the centrifugal force resulting from the rotating platform, separation and purification may be achieved economically without requiring additional equipments.Type: GrantFiled: December 10, 2010Date of Patent: December 9, 2014Assignee: Korea Advanced Institute of Science and Technology (KAIST)Inventors: Tae Seok Seo, Jae Hwan Jung, Seok Jin Choi
-
Patent number: 8878928Abstract: A multiple ROI (region of interest) setting method and apparatus in scalable video coding and an ROI reconstructing method and apparatus are provided. The multiple ROI setting apparatus includes: an ROI setting unit which sets at least one or more ROIs and allocates ROI identification numbers to the each of ROIs; a mapping unit which allocates at least one or more slice group identification numbers to the at least one or more ROI identification numbers; and a message generating unit which generates a message including ROI-associated information, slice-group-associated information, mapping information on mapping of the ROI identification number to the at least one or more slice group identification numbers, and scalability information.Type: GrantFiled: May 28, 2013Date of Patent: November 4, 2014Assignees: Electronics and Telecommunications Research Institute, Korea Advanced Institute of Science and Technology (KAIST)Inventors: Jung Won Kang, Jae Gon Kim, Jin Woo Hong, Yong Man Ro, Tae Meon Bae, Cong Thang Truong