Abstract: A novel biologically active substance named Islets-Activating Protein obtained from the cultivation of the miocroorganism Bordetella and having insulin secretion promoting action as well as glucose tolerance improving action for mammals.

Abstract: New antibiotic 5057B and process for its preparation. Antibiotic 5057B itself is an acidic material, and its sodium salt has the following physical and chemical properties:(1) Colorless needles(2) Melting point: 143.degree.-145.degree. C.(3) Elementary analysis (Found %): C, 59.96; H, 9.03; O, 27.60; Na, 3.41(4) Specific rotation: [.alpha.].sub.D.sup.25 =+5.5.degree. (C 1, CHCl.sub.3)(5) Maximum absorption in ultraviolet absorption spectrum: .lambda..sub.max.sup.MeOH (E.sub.1 cm.sup.1%) 290 nm (0.88)(6) Characteristic absorption (cm.sup.-1) in infrared absorption spectrum (taken with the potassium bromide tablet: 3480, 3000, 2970, 2812, 1719, 1645, 1595, 1465, 1385, 1160, 1100, 1035, 980(7) Solubility: soluble in methanol, ethanol, ethyl acetate, chloroform, ether, acetone, and benzene and so forth; insoluble in water(8) Color reaction: positive in the 2,4-dinitrophenylhydrazine reaction; negative in the ninhydrin reaction and the vanilline-sulfuric acid reaction; colors with I.sub.2 gas.

Abstract: A dehumidifying container comprises an inner container having an opening at its upper end, and a bottom portion. The inner container is filled with a dehumidifying agent and has a discharge pipe provided upright at the center of its bottom portion. The discharge pipe has at least one slit in a wall thereof and an open lower end which protrudes downwardly through the bottom portion of the inner container. The inner container is detachably fitted into an outer container in such a manner that a space having a predetermined volume is formed between the respective bottom portions of the inner and outer containers. The dehumidifying agent absorbs moisture from the air and the so formed solution of the agent flows readily through the or each slit in the discharge pipe out through the open lower end of the pipe, and into said space. The upper end of the pipe is also open to assist such flow.

Abstract: Antibiotic Actinomadura-L-31 A has the characteristics as the hydrochloride salt:appearance: white or pale yellow powdermelting point: non-clear melting pointspecific rotation: [.alpha.].sub.D.sup.25 -34.degree. (C: 0.5, pH: 7.5 water)elementary analysis: (found) C: 51.71%; H: 6.23%; O: 21.03%; N: 13.94%; S: 5.82%; Cl: 1.17%constitutive aminoacids: aspartic acid; glutamic acid; glycin; valine; phenylalanine; histidine; leucine; tryptophanultraviolet absorption spectrum: FIG. 1, maximum absorption:280 nm: E.sub.1 cm.sup.1% =45.2290 nm: shoulder E.sub.1 cm.sup.1% =38infrared spectrum: FIG. 2, absorption (cm.sup.-1) 3350, 3050, 2950, 1660, 1530, 1430, 1395, 1340, 1255, 1235, 1100, 745, 700Antibiotic Actinomadura-L-31 B has the characteristics as the hydrochloride salt:appearance: white to pale yellow powdermelting point: non-clear melting pointspecific rotation: [.alpha.].sub.D.sup.25 -26.degree. (C: 0.5; pH: 7.5 water)elementary analysis: (found) C: 51.10%; H: 6.34%; O: 20.75% N: 14.81%; S: 5.91%; Cl: 1.

Abstract: A herbicidal composition comprises an active ingredient having the formula ##STR1## wherein R.sup.1 represents a C.sub.1 -C.sub.5 alkoxy group; R.sup.2 represents hydrogen atom, or a C.sub.1 -C.sub.5 alkyl group.

Abstract: Benzaminoethylphenoxycyclohexylacetic acid derivatives having the formula ##STR1## wherein R.sup.1 represents hydrogen atom, a halogen atom, hydroxyl group, a lower alkyl group or a lower alkoxy group; n is 1 or 2; and R.sup.2 represents hydrogen atom, a lower alkyl group which can have a substituent of phenyl group, a lower alkoxycarbonyl group, 3,3,5-trimethylcyclohexyloxycarbonyl group or a heterocyclic group; hexadecyl group; phenyl group which can have a substituent of a lower alkyl group, a lower alkoxy group, a lower alkoxycarbonyl group or a halogen atom; a cyclohexyl group or .alpha.-[4-(4-chlorobenzaminoethyl) phenoxy]-.alpha.-cyclohexylacetoxycyclohexyl group a antihyperlipidemic compositions thereof.

Abstract: A miticidal method comprises applying a miticidal composition comprising Lysocellin having the formula ##STR1## or its salt or ester.

Abstract: Novel substituted oxy-cyclohexylacetic acid derivatives as antihyperlipidemic agents are given. The compounds have the formula ##STR1## wherein n is 1 or 2; m is 0, 1 or 2; R.sub.1 represents a halogen atom, trifluoromethyl, a lower alkyl, a lower alkoxy, a lower alkylcarbonyl, dimethylphenylmethyl, cyclohexyl, phenyl, halogenophenyl, phenoxy or halogenophenoxy group, and two of R.sub.1 groups can be bonded to form an orthocondensed saturated alkylene ring; Hal represents a halogen atom; and R.sub.2 represents a hydrogen atom or a lower alkyl group.

Abstract: Geldanamycin derivatives the following formula ##STR1## wherein R.sup.1 represents a saturated alkylamino which should have at least two carbon atoms, an unsaturated alkylamino, a substituted lower alkylamino, cycloalkylamino, pyrrolidino or aralkylamino group or methoxy group; R.sup.2 represents hydrogen atom, a halogen atom or a lower mono or dialkylamino; when R.sup.1 is methoxy group, R.sup.2 is a halogen atom or lower alkylamino group, or ##STR2## and Geldanamycin derivative is 8,9-epoxy-Geldanamycin. The compounds are effective as antitumor drugs.

Abstract: Benzoyl phenoxy acetic acid derivatives having the formula ##STR1## wherein R.sub.1 represents hydrogen or halogen atom or a lower alkyl group or a lower alkoxyl group; and R.sub.2 represents hydrogen atom or a lower alkyl group which impart excellent antihyperlipidemic activity are provided.

Abstract: Anti-inflammatory agent comprises an active ingredient of benzoyl derivative having the formula ##STR1## WHEREIN R.sub.1 represents hydrogen, hydroxy, C.sub.1-8 alkyl or C.sub.1-8 alkoxy,R.sub.2 represents hydrogen, halogen, hydroxy, vinyl, C.sub.1-8 alkyl or C.sub.1-8 alkoxy,A represents carbonyl, methylene or a single bond, andN is an integer of 1 to 4.

Abstract: SY-1 substance has the following formula: ##STR1## The SY-1 substance and esters and salts thereof are antibiotics which have antibacterial, antifungal, antiviral and anticoccidial activity and also increase feed-utilization efficiency in ruminants.

Abstract: Anti-inflammatory agent comprises an active ingredient of benzoyl derivative having the formula ##STR1## WHEREIN R.sub.1 represents hydrogen, halogen, hydroxy, C.sub.1-8 alkyl or C.sub.1-8 alkoxy,R.sub.2 represents hydrogen, halogen, hydroxy, vinyl, C.sub.1-8 alkyl or C.sub.1-8 alkoxy,A represents carbonyl, methylene or a single bond, andn is an integer of 1 to 4.

Abstract: Methyl methionine sulfonium salts having the formula ##STR1## wherein R.sup.- represents an inorganic or organic anion are used in remedy for renal diseases and secondary hyper lipoidemia caused by renal diseases.

Abstract: Neoschizophyllan is produced by an ultrasonication of Schizophyllan which is extracted from a culture solution of Schizophyllum commune Fries or a fruit body thereof.

Abstract: Diarrhea of young pig and calf in the sucking or weaning period is prevented by an oral dosage of .beta.-galactosidase.

Abstract: Salinomycin is applied as an active ingredient of a miticidal composition to mites.

Abstract: Streptovaricinone C derivatives of the formula ##STR1## wherein Z is a C.sub.1.sub.-12 alkyl, an aryl, a hydroxyalkyl, an alkenyl, a ketonyl, a furyl-oxoalkyl, a thienyl-oxoalkyl, a phenacyl, a carbamylalkyl, a benzyl, a phenoxyalkyl, a cyanoalkyl, a phenethyl, a benzoyloxyethyl, a p-chlorophenacyl, a p-methoxyphenacyl, a p-nitrobenzyl, a p-methylbenzyl, an alkanoyl, a benzoyl, a benzenesulfonyl, an alkylsulfonyl or an alkoxycarbonyl group, are antibiotics.