Abstract: A 3D integrated circuit device can include a substrate, a thermal interface layer and at least one die, at least one device layer bonded between the thermal interface layer and the at least one die, wherein the thermal interface layer enhances conductive heat transfer between the at least one device layer and the at least one die, and a heat sink located adjacent to a heat spreader, wherein the thermal interface layer, the at least one die and the at least one device layer are located between the heat spreader and the substrate.

Abstract: A 3D integrated circuit device can include a substrate, a thermal interface layer and at least one die, at least one device layer bonded between the thermal interface layer and the at least one die, wherein the thermal interface layer enhances conductive heat transfer between the at least one device layer and the at least one die, and a heat sink located adjacent to a heat spreader, wherein the thermal interface layer, the at least one die and the at least one device layer are located between the heat spreader and the substrate.

Abstract: A method and system for noninvasively treating a neurodegenerative disorder, can involve determining characteristics indicative of physical attributes of a central nervous system, the characteristics including parameters for diminishing adverse impacts of a magnetothermal stimulation treatment for a neurodegenerative disorder with respect to the central nervous system, and applying as a part of the magnetothermal stimulation treatment and based on the characteristics of the physical attributes of the central nervous system, a magnetic field to the brain for a thermal stimulation of neuron cells within the brain.

Abstract: Devices comprising multi-compartment fluidic cell with multiple inlets. Compartments can be separated from one another using soft seals. The main cell can be located between two adjacent secondary cells. The main cell carries the main flow while the secondary cells can carry either the main flow or any auxiliary flows. The flow in the multi-compartment cells minimizes fluid leakage and causes reduced pressure difference between the main cell and the two secondary cells especially under similar flow conditions.

Abstract: Methods and systems for analyzing the detection enhancement of rectangular microcantilevers with long-slit microsensors. The deflection profile of the microcantilevers can he compared with that of typical rectangular microcantilevers under presence of dynamic disturbances. Various force-loading conditions are considered. The theory of linear elasticity for thin beams is used to obtain the deflection related quantities. The disturbance in these quantities can be obtained based on wave propagation and beam vibration theories.

Abstract: Devices utilized to enhance insulating properties at high temperatures. Such devices can include two gas compartments. A main gas compartment can function as a main layer and generally contains a layer of a gas (e.g., Xenon) having a relatively small thermal conductivity. The plates of the main gas layer can be separated by a soft seal, so that the main gas does not leak and the main layer expands easily. A second gas compartment can be configured as a vented compartment filled with air. At high temperatures, the main gas expands while the secondary gas volume shrinks. Since the main gas possesses a lower thermal conductivity, the effective resistance of the device increases, causing an enhancement in the insulating properties at large operating temperatures. A series of gas compartments can be utilized for additional enhancement in insulating properties.

Abstract: Low-density lipoprotein (LDL) transport while incorporating the thickening of the arterial wall and cholesterol lipid accumulation can be analyzed. A multi-layered model can be adopted to represent the heterogeneity using the Darcy-Brinkman and Staverman filtration equations to describe transport within the porous layers of the wall. The fiber matrix model can be utilized to represent the cholesterol lipid accumulation and the resulting variable properties. The impact of atherosclerotic wall thickening is shown to be negligible in the axial direction, but is found to be considerable in the radial direction within intima. The reference values of intima's porosity and effective fiber radius are obtained through the fiber matrix model, which characterizes the micro-structure within the intima.

Abstract: Methods and systems for analyzing the effects of Fluid Solid Interactions (FSI) and pulsation on the transport of Low-Density Lipoprotein (LDL) through an elastic wall (e.g., an arterial wall). A comprehensive multi-layer model for both LDL transport as well as FSI can be analyzed and compared with existing results in limiting cases. The model takes into account the complete multi-layered LDL transport while incorporating FSI aspects to enable a comprehensive study of the deformation effect on the pertinent parameters of the transport processes within an artery. Since the flow inside an artery is time-dependent, the impact of pulsatile flow is also analyzed with and without FSI. The consequence of different factors on LDL transport in an artery is also analyzed.

Abstract: Devices for the control of flow rate and thermal conditions using two-layered thin films separated by flexible complex seals. The plates of an upper thin film are separated by a sealing assembly. The sealing assembly is composed of an elastic soft seal separating closed voids of stagnant fluid and in contact with the upper plate of the device as it is the heated plate. The lower and the upper plates of the lower thin film can be separated by an elastic soft seal. The lower and upper thin films are named as main and secondary layers, respectively. Both the upper plate of the secondary layer and the lower plate of the main layer are fixed while the intermediate plate and is free to move in the vertical direction. When the pressure or the working temperature in the secondary layer increases, the secondary layer expands causing the main layer thickness to shrink. This reduces the main layer flow rate and temperature gradients within the main layer.

Abstract: Devices and methods for increasing and decreasing cooling capacity as thermal load increases by utilizing bimaterial. For increasing the cooling capacity, the upper plate of a thin film microchannel can be configured from a bimaterial, such that the upper layer possesses a higher linear thermal expansion coefficient than that of the lower layer material. Excessive heating causes the coolant temperature to increase which in turn heats the upper plate. As such, the upper plate bends outward allowing for more coolant to flow within the thin film. For decreasing the cooling capacity, the upper plate can be configured from a bimaterial such that its lower layer has a higher linear thermal expansion coefficient than that of the upper layer material. Excessive heating can cause the coolant temperature to increase, which in turn heats the upper plate. As such, the upper plate can bend inward resulting in less coolant flow within the thin film.

Abstract: A cooling enhancement apparatus includes a first substrate and a second substrate, the first substrate having a face in contact with at least one hot medium and having another face in contact with a secondary gas. The second substrate includes a face in contact with the secondary gas and has the other face in contact with a main gas. The faces of the first and second substrates in contact with the secondary gas generally oppose each other. One or more flexible seals can be attached to the first substrate and to the second substrate to form one or more closed enclosures including the secondary gas so that the second substrate moves relative to the first substrate when the secondary gas undergoes volumetric thermal expansion.

Abstract: A method and system for analyzing transient thermal response of a packed bed under Local Thermal Non-Equilibrium is disclosed. Heat transfer performances in terms of the fluid, solid, and total Nusselt number are obtained. Qualitative analyses of the effects of thermal conduction at the wall on the total heat exchange between the solid and fluid phases within the heat flux bifurcation region are also performed. Both the transient and diffusion aspects are considered in the solid and fluid phases along with the convection and the fluid-solid interaction. The analytical solution for transient response of a packed bed subject to a constant temperature boundary condition is derived. The heat flux bifurcation phenomenon in a porous media is investigated for temporal conditions, and the analytical two-dimensional thermal behavior and the LTE model is examined under transient conditions. Further, the response time towards steady state conditions is investigated.

Abstract: Disclosed herein are devices comprising at least one flexible seal, at least one flexible complex seal having at least one closed cavity containing a fluid, or a combination thereof. The devices may comprise at least one immobile and inflexible substrate and at least one mobile and inflexible substrate capable of movement due to the flexible seal, the flexible complex seal, or both. The flexible complex seals comprise at least one closed cavity comprising a fluid, such as a gas or a liquid. As disclosed, the presence or absence of heat will cause the mobile and inflexible substrate to move. The movement will increase or decrease the fluid amount or fluid flow rate in the primary fluid layer. Also disclosed are methods for enhancing the insulating properties of insulating assemblies.