Patents Assigned to KANAGAWA INSTITUTE OF INDUSTRIAL SCIENCE AND TECHNOLOGY
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Patent number: 11851344Abstract: A complex oxide ceramic according to an embodiment is a complex oxide ceramic including a rare earth element and at least one element selected from among molybdenum, tungsten, and vanadium. An example of the rare earth element is at least one species selected from among La, Ce, and Gd.Type: GrantFiled: July 16, 2019Date of Patent: December 26, 2023Assignees: TOKYO INSTITUTE OF TECHNOLOGY, KANAGAWA INSTITUTE OF INDUSTRIAL SCIENCE AND TECHNOLOGY, NGK SPARK PLUG CO., LTD.Inventors: Akira Nakajima, Takumi Matsumoto, Sachiko Matsushita, Toshihiro Isobe, Kayano Sunada
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Publication number: 20230203116Abstract: An object is to provide a peptide gelling agent which gels under physiological conditions and which has a relatively short chain length, and a sustained-release gel based on it. Provided is a hydrogelling self-assembling peptide comprising one or two core peptides consisting of an amino acid sequence represented by the following formula: Xaa-Yaa-Zaa-Yaa-Xaa-Yaa-Zaa-Yaa-Xaa, wherein Xaa is independently Ile or Met, Yaa is independently Asp, Glu, Lys, or Arg, and Zaa is independently Ala or Gly, and wherein the full length of the amino acid sequence constituting said self-assembling peptide is 25 amino acids or less.Type: ApplicationFiled: July 29, 2021Publication date: June 29, 2023Applicants: NATIONAL UNIVERSITY CORPORATION TOKYO MEDICAL AND DENTAL UNIVERSITY, KANAGAWA INSTITUTE OF INDUSTRIAL SCIENCE AND TECHNOLOGYInventors: Takahiro MURAOKA, Atsuya YAGUCHI, Itsuki AJIOKA, Go WATANABE
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Publication number: 20230143373Abstract: A medical apparatus includes a treatment mechanism, a slave actuator, an operation control unit, and a parameter acquisition unit. The treatment mechanism is used for treating a patient. The slave actuator causes the treatment mechanism to perform the treatment. The operation control unit calculates the control parameters related to the force tactile sensation, based on the information about the position that is detected along with the treatment and controls the operation of the slave actuator for causing the treatment mechanism to perform the treatment, based on the control parameters related to the force tactile sensation. The parameter acquisition unit acquires the control parameters related to the force tactile sensation.Type: ApplicationFiled: March 29, 2021Publication date: May 11, 2023Applicants: KANAGAWA INSTITUTE OF INDUSTRIAL SCIENCE AND TECHNOLOGY, KEIO UNIVERSITYInventors: Tomoyuki SHIMONO, Hiroshi ASAI, Kouhei OHNISHI, Takuya MATSUNAGA, Hironao KOBAYASHI, Masaya NAKAMURA, Mitsuru YAGI
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Patent number: 11607871Abstract: Disclosed are a separator for lipid bilayer membrane formation capable of forming a lipid bilayer membrane with excellent properties, wherein the separator for lipid bilayer membrane formation has sufficient mechanical strength and can be easily manufactured in a large scale by using a general-purpose machine without need of using an expensive machine, and a method of producing the separator. The separator for lipid bilayer membrane formation includes a thin film having one or more through holes and made of a resin capable of being wet-etched, and reinforcing layers covering both surfaces of the thin film and made of a resin capable of being wet-etched. The reinforcing layers cover the whole area of the thin film, except for the through holes and the peripheries thereof, and each through hole has a tapered cross-sectional shape.Type: GrantFiled: January 15, 2019Date of Patent: March 21, 2023Assignees: KANAGAWA INSTITUTE OF INDUSTRIAL SCIENCE AND TECHNOLOGY, TORAY ENGINEERING CO., LTD.Inventors: Toshihisa Osaki, Masatoshi Hayakawa, Koki Kamiya, Miharu Kaneko, Hideo Uehara, Katsufumi Araki, Ayumi Konda, Hajime Hirata, Toshiyuki Ura
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Publication number: 20220326204Abstract: The present invention provides a measuring device which includes: a first container and a second container that are arranged adjacent to each other; and a partition wall provided between the first and second containers, the partition wall having a through hole(s) for forming a lipid bilayer(s). In this measuring device, a gas flow path(s) having a hydrophobic surface is/are formed in at least one of the first and second containers; the gas flow path(s) has/have an inlet and an outlet; the inlet and the outlet each communicate with the exterior of the measuring device; the gas flow path(s) open(s) into the container in which it/they is/are formed; and a gas flowing in the gas flow path(s) contacts the droplet filled in the container.Type: ApplicationFiled: October 2, 2020Publication date: October 13, 2022Applicant: KANAGAWA INSTITUTE OF INDUSTRIAL SCIENCE AND TECHNOLOGYInventors: Tetsuya YAMADA, Toshihisa OSAKI, Hisatoshi MIMURA, Hirotaka SUGIURA, Shoji TAKEUCHI
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Patent number: 11447696Abstract: A fluorescent member according to present invention is composed of a sintered body for wavelength conversion containing a matrix containing magnesium oxide and magnesium hydroxide as main components, and phosphor particles dispersed in the matrix. A thermal conductivity of the fluorescent member is preferably 5 W/(m·K) or higher. A fluorescent member having both a satisfactory thermal conductivity and a satisfactory fluorescent property is provided without requiring a high-temperature sintering process (a high-temperature process at a temperature higher than 250° C.). Further, a method for manufacturing such a fluorescent member and a light-emitting apparatus using such a fluorescent member are provided.Type: GrantFiled: July 22, 2020Date of Patent: September 20, 2022Assignee: KANAGAWA INSTITUTE OF INDUSTRIAL SCIENCE AND TECHNOLOGYInventors: Junichi Tatami, Emi Takahashi, Takuma Takahashi
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Publication number: 20220228113Abstract: Provided is a hair follicle germ capable of forming a hair shaft-like structure in vitro simply and within a short period of time. A method of producing a hair follicle germ includes: inoculating epithelial cells and mesenchymal cells; maintaining the epithelial cells and the mesenchymal cells in a culture solution in which (a) laminin and entactin, and/or (b) type IV collagen is dispersed; and co-culturing the epithelial cells and the mesenchymal cells in a culture solution to form a hair follicle germ.Type: ApplicationFiled: August 7, 2019Publication date: July 21, 2022Applicants: National University Corporation Yokohama National University, Kanagawa Institute of Industrial Science and TechnologyInventors: Junji Fukuda, Tatsuto Kageyama, Akihiro Shimizu, Rikuma Nakajima, Riki Anakama
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Patent number: 11276871Abstract: To provide an electrolyte membrane that exhibits high proton conductivity even at low humidity, the electrolyte membrane includes a composite membrane including: a microporous polyolefin membrane that has an average pore diameter of 1 to 1000 nm and a porosity of 50 to 90% and that can be impregnated with a solvent having a surface free energy of 28 mJ/m2 or more, and an electrolyte containing a perfluorosulfonic acid polymer having an EW of 250 to 850 loaded into the pores of the microporous polyolefin membrane, wherein the membrane thickness of the composite membrane is 1 to 20 ?m.Type: GrantFiled: May 31, 2017Date of Patent: March 15, 2022Assignees: TOKYO INSTITUTE OF TECHNOLOGY, TEIJIN LIMITED, KANAGAWA INSTITUTE OF INDUSTRIAL SCIENCE AND TECHNOLOGYInventors: Takeo Yamaguchi, Yuhei Oshiba, Hidenori Ohashi, Jin Tomatsu, Koji Furuya, Takao Ohno, Mami Nanbu
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Publication number: 20220041983Abstract: Provided are a hair follicle germ having excellent hair growth-related properties, a method of producing a hair follicle germ, and a method of activating cells contained in a hair follicle germ. The hair follicle germ includes: epithelial cells; mesenchymal cells; and mesenchymal stem cells. The method of producing a hair follicle germ includes co-culturing epithelial cells, mesenchymal cells, and mesenchymal stem cells to form a hair follicle germ.Type: ApplicationFiled: October 15, 2019Publication date: February 10, 2022Applicants: National University Corporation Yokohama National University, Kanagawa Institute of Industrial Science and TechnologyInventors: Junji Fukuda, Tatsuto Kageyama, Yoshiki Tate
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Publication number: 20210282795Abstract: A medical gripping device includes a housing, a gripping mechanism at one end of the housing, an operation unit, and a reaction force actuator and a gripping actuator installed in the housing. The operation unit is operated by a gripping operation of an operator, and the reaction force actuator applies an operation reaction force to the operation unit. The gripping actuator causes the gripping mechanism to perform a gripping operation. A control unit controls a force and a position that are output by the gripping actuator in an operation of the gripping mechanism in accordance with an operation with respect to the operation unit, and controls a force and a position that are output by the reaction force actuator in an operation of applying the operation reaction force to the operation unit in accordance with a reaction from a gripped object with respect to the gripping mechanism.Type: ApplicationFiled: June 7, 2019Publication date: September 16, 2021Applicants: KANAGAWA INSTITUTE OF INDUSTRIAL SCIENCE AND TECHNOLOGY, KEIO UNIVERSITYInventors: Tomoyuki SHIMONO, Hikaru SASAKI, Kouhei OHNISHI, Shunsuke SHIBAO, Takahiro MIZOGUCHI, Takuya MATSUNAGA, Eriko ABIKO, Masaaki NISHIMOTO, Mika AOKI
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Patent number: 11111433Abstract: Provided are a transparent fluorescent sialon ceramic having fluorescence and optical transparency; and a method of producing the same. Such a transparent fluorescent sialon ceramic includes a sialon phosphor which contains a matrix formed of a silicon nitride compound represented by the formula Mx(Si,Al)y(N,O)z (here, M represents at least one selected from the group consisting of Li, alkaline earth metals, and rare earth metals, 0?x/z<3, and 0<y/z<1) and a luminescent center element.Type: GrantFiled: March 6, 2015Date of Patent: September 7, 2021Assignees: NATIONAL UNIVERSITY CORPORATION YOKOHAMA NATIONAL UNIVERSITY, KANAGAWA INSTITUTE OF INDUSTRIAL SCIENCE AND TECHNOLOGYInventors: Takuma Takahashi, Junichi Tatami, Yuki Sano, Takehiko Tanaka, Masahiro Yokouchi
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Patent number: 11078416Abstract: Provided are a transparent fluorescent sialon ceramic having fluorescence and optical transparency; and a method of producing the same. Such a transparent fluorescent sialon ceramic includes a sialon phosphor which contains a matrix formed of a silicon nitride compound represented by the formula Mx(Si,Al)y(N,O)z (here, M represents at least one selected from the group consisting of Li, alkaline earth metals, and rare earth metals, 0?x/z<3, and 0<y/z<1) and a luminescent center element.Type: GrantFiled: March 6, 2015Date of Patent: August 3, 2021Assignees: NATIONAL UNIVERSITY CORPORATION YOKOHAMA NATIONAL UNIVERSITY, KANAGAWA INSTITUTE OF INDUSTRIAL SCIENCE AND TECHNOLOGYInventors: Takuma Takahashi, Junichi Tatami, Yuki Sano, Takehiko Tanaka, Masahiro Yokouchi
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Publication number: 20210163918Abstract: Provided are a cell-containing hydrogel body and a method of producing the same, which enable simple and effective control of the size of a boundary surface for an interaction between cells. The method of producing a cell-containing hydrogel body includes: forming, under a gas phase, a first hydrogel droplet on a surface of a substrate, the first hydrogel droplet containing first cells being dispersed therein and a first hydrogel polymer; forming, under a gas phase, a second hydrogel droplet on the surface, the second hydrogel droplet containing second cells being dispersed therein and a second hydrogel polymer, the second hydrogel droplet being combined with the first hydrogel droplet; and forming, under a gas phase, a cell-containing hydrogel body on the surface by gelling a hydrogel droplet-combined body including a first droplet portion derived from the first hydrogel droplet and a second droplet portion derived from the second hydrogel droplet.Type: ApplicationFiled: April 16, 2019Publication date: June 3, 2021Applicants: National University Corporation Yokohama National University, Kanagawa Institute of Industrial Science and TechnologyInventors: Junji Fukuda, Tatsuto Kageyama
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Patent number: 10982140Abstract: A nitride phosphor particle dispersion-type sialon ceramic of the present invention includes a matrix formed of a sialon-based compound; and at least one nitride phosphor which is dispersed in the matrix and contains a luminescence center element.Type: GrantFiled: August 25, 2017Date of Patent: April 20, 2021Assignees: KANAGAWA INSTITUTE OF INDUSTRIAL SCIENCE AND TECHNOLOGY, NATIONAL UNIVERSITY CORPORATION YOKOHAMA NATIONAL UNIVERSITYInventors: Takuma Takahashi, Junichi Tatami, Ippei Kokubun, Masahiro Yokouchi
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Publication number: 20210107134Abstract: A haptic transmission system includes a master device and a slave device. The master device controls position and force in an operation of the master device based on information acquired from the operation of the master device and information relating to a response of the slave device, and compensates for a communication delay in a communication path with respect to the control of force. The slave device controls speed and force in an operation of the slave device based on information acquired from the operation of the slave device and information relating to control from the master device.Type: ApplicationFiled: March 7, 2019Publication date: April 15, 2021Applicants: KANAGAWA INSTITUTE OF INDUSTRIAL SCIENCE AND TECHNOLOGY, KEIO UNIVERSITYInventors: Tomoyuki SHIMONO, Takahiro MIZOGUCHI, Kouhei OHNISHI, Tetsuya TASHIRO
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Publication number: 20210079345Abstract: Provided are a method and kit for growth of hair follicle epithelial stem cells on a large scale while maintaining their hair regeneration ability. The culture method for hair follicle epithelial stem cells includes: an accumulating step of forming an accumulation of hair follicle epithelial stem cells by inoculating a cell culture vessel with the hair follicle epithelial stem cells; a mixing step of producing a mixture of an extracellular matrix component and the accumulation of the hair follicle epithelial stem cells by adding the extracellular matrix component to the accumulation of the hair follicle epithelial stem cells; and a culturing step of culturing the hair follicle epithelial stem cells by adding a medium to the mixture. The culture kit for hair follicle epithelial stem cells includes: a cell culture vessel formed of a material having oxygen permeability; an extracellular matrix component; and a medium.Type: ApplicationFiled: February 4, 2019Publication date: March 18, 2021Applicants: National University Corporation Yokohama National University, Kanagawa Institute of Industrial Science and TechnologyInventors: Junji Fukuda, Tatsuto Kageyama, Sugi Hirano
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Patent number: 10865373Abstract: The present invention provides a method for manufacturing a regular and high-density regenerated hair follicle primordium aggregation similar to the hair follicle tissue of a mammal in a simple manner. A regenerated hair follicle primordium aggregation manufacturing method of the present invention includes a step of forming hair follicle primordia by inoculating a microwell plate, which includes regularly arranged microwell portions, with mesenchymal cells and epithelial cells and culturing a mixture of the cells while supplying oxygen thereto.Type: GrantFiled: October 26, 2016Date of Patent: December 15, 2020Assignees: National University Corporation Yokohama National University, Kanagawa Institute of Industrial Science and TechnologyInventors: Junji Fukuda, Tatsuto Kageyama, Chisa Yoshimura, Kisaki Onishi
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Publication number: 20200346444Abstract: Disclosed are a separator for lipid bilayer membrane formation capable of forming a lipid bilayer membrane with excellent properties, wherein the separator for lipid bilayer membrane formation has sufficient mechanical strength and can be easily manufactured in a large scale by using a general-purpose machine without need of using an expensive machine, and a method of producing the separator. The separator for lipid bilayer membrane formation includes a thin film having one or more through holes and made of a resin capable of being wet-etched, and reinforcing layers covering both surfaces of the thin film and made of a resin capable of being wet-etched. The reinforcing layers cover the whole area of the thin film, except for the through holes and the peripheries thereof, and each through hole has a tapered cross-sectional shape.Type: ApplicationFiled: January 15, 2019Publication date: November 5, 2020Applicants: KANAGAWA INSTITUTE OF INDUSTRIAL SCIENCE AND TECHNOLOGY, TORAY ENGINEERING CO., LTD.Inventors: Toshihisa OSAKI, Masatoshi HAYAKAWA, Koki KAMIYA, Miharu KANEKO, Hideo UEHARA, Katsufumi ARAKI, Ayumi KONDA, Hajime HIRATA, Toshiyuki URA
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Publication number: 20200208106Abstract: Provided is a manufacturing method for a plurality of regenerated hair follicle germs, including a step including simultaneously inoculating a microwell plate including regularly arranged microwell portions with mesenchymal cells and epithelial cells, and co-culturing the mesenchymal cells and the epithelial cells using a medium containing a fibroblast growth factor while supplying oxygen to the mesenchymal cells and the epithelial cells from at least an upper surface and a bottom surface of the microwell plate, to thereby form hair follicle germs in the microwell portions, the microwell plate being formed of a material having oxygen permeability. Also provided is a kit for hair regeneration, including: a microwell plate including regularly arranged microwell portions; and a fibroblast growth factor, wherein the microwell plate is formed of a material having oxygen permeability.Type: ApplicationFiled: August 16, 2018Publication date: July 2, 2020Applicants: National University Corporation Yokohama National University, Kanagawa Institute of Industrial Science and TechnologyInventors: Junji Fukuda, Tatsuto Kageyama, Akihiro Shimizu
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Publication number: 20190267655Abstract: To provide an electrolyte membrane that exhibits high proton conductivity even at low humidity, the electrolyte membrane includes a composite membrane including: a microporous polyolefin membrane that has an average pore diameter of 1 to 1000 nm and a porosity of 50 to 90% and that can be impregnated with a solvent having a surface free energy of 28 mJ/m2 or more, and an electrolyte containing a perfluorosulfonic acid polymer having an EW of 250 to 850 loaded into the pores of the microporous polyolefin membrane, wherein the membrane thickness of the composite membrane is 1 to 20 ?m.Type: ApplicationFiled: May 31, 2017Publication date: August 29, 2019Applicants: TOKYO INSTITUTE OF TECHNOLOGY, TEIJIN LIMITED, KANAGAWA INSTITUTE OF INDUSTRIAL SCIENCE AND TECHNOLOGYInventors: Takeo YAMAGUCHI, Yuhei OSHIBA, Hidenori OHASHI, Jin TOMATSU, Koji FURUYA, Takao OHNO, Mami NANBU