Patents Assigned to KANAGAWA INSTITUTE OF INDUSTRIAL SCIENCE AND TECHNOLOGY
  • Patent number: 11851344
    Abstract: A complex oxide ceramic according to an embodiment is a complex oxide ceramic including a rare earth element and at least one element selected from among molybdenum, tungsten, and vanadium. An example of the rare earth element is at least one species selected from among La, Ce, and Gd.
    Type: Grant
    Filed: July 16, 2019
    Date of Patent: December 26, 2023
    Assignees: TOKYO INSTITUTE OF TECHNOLOGY, KANAGAWA INSTITUTE OF INDUSTRIAL SCIENCE AND TECHNOLOGY, NGK SPARK PLUG CO., LTD.
    Inventors: Akira Nakajima, Takumi Matsumoto, Sachiko Matsushita, Toshihiro Isobe, Kayano Sunada
  • Publication number: 20230203116
    Abstract: An object is to provide a peptide gelling agent which gels under physiological conditions and which has a relatively short chain length, and a sustained-release gel based on it. Provided is a hydrogelling self-assembling peptide comprising one or two core peptides consisting of an amino acid sequence represented by the following formula: Xaa-Yaa-Zaa-Yaa-Xaa-Yaa-Zaa-Yaa-Xaa, wherein Xaa is independently Ile or Met, Yaa is independently Asp, Glu, Lys, or Arg, and Zaa is independently Ala or Gly, and wherein the full length of the amino acid sequence constituting said self-assembling peptide is 25 amino acids or less.
    Type: Application
    Filed: July 29, 2021
    Publication date: June 29, 2023
    Applicants: NATIONAL UNIVERSITY CORPORATION TOKYO MEDICAL AND DENTAL UNIVERSITY, KANAGAWA INSTITUTE OF INDUSTRIAL SCIENCE AND TECHNOLOGY
    Inventors: Takahiro MURAOKA, Atsuya YAGUCHI, Itsuki AJIOKA, Go WATANABE
  • Publication number: 20230143373
    Abstract: A medical apparatus includes a treatment mechanism, a slave actuator, an operation control unit, and a parameter acquisition unit. The treatment mechanism is used for treating a patient. The slave actuator causes the treatment mechanism to perform the treatment. The operation control unit calculates the control parameters related to the force tactile sensation, based on the information about the position that is detected along with the treatment and controls the operation of the slave actuator for causing the treatment mechanism to perform the treatment, based on the control parameters related to the force tactile sensation. The parameter acquisition unit acquires the control parameters related to the force tactile sensation.
    Type: Application
    Filed: March 29, 2021
    Publication date: May 11, 2023
    Applicants: KANAGAWA INSTITUTE OF INDUSTRIAL SCIENCE AND TECHNOLOGY, KEIO UNIVERSITY
    Inventors: Tomoyuki SHIMONO, Hiroshi ASAI, Kouhei OHNISHI, Takuya MATSUNAGA, Hironao KOBAYASHI, Masaya NAKAMURA, Mitsuru YAGI
  • Patent number: 11607871
    Abstract: Disclosed are a separator for lipid bilayer membrane formation capable of forming a lipid bilayer membrane with excellent properties, wherein the separator for lipid bilayer membrane formation has sufficient mechanical strength and can be easily manufactured in a large scale by using a general-purpose machine without need of using an expensive machine, and a method of producing the separator. The separator for lipid bilayer membrane formation includes a thin film having one or more through holes and made of a resin capable of being wet-etched, and reinforcing layers covering both surfaces of the thin film and made of a resin capable of being wet-etched. The reinforcing layers cover the whole area of the thin film, except for the through holes and the peripheries thereof, and each through hole has a tapered cross-sectional shape.
    Type: Grant
    Filed: January 15, 2019
    Date of Patent: March 21, 2023
    Assignees: KANAGAWA INSTITUTE OF INDUSTRIAL SCIENCE AND TECHNOLOGY, TORAY ENGINEERING CO., LTD.
    Inventors: Toshihisa Osaki, Masatoshi Hayakawa, Koki Kamiya, Miharu Kaneko, Hideo Uehara, Katsufumi Araki, Ayumi Konda, Hajime Hirata, Toshiyuki Ura
  • Publication number: 20220326204
    Abstract: The present invention provides a measuring device which includes: a first container and a second container that are arranged adjacent to each other; and a partition wall provided between the first and second containers, the partition wall having a through hole(s) for forming a lipid bilayer(s). In this measuring device, a gas flow path(s) having a hydrophobic surface is/are formed in at least one of the first and second containers; the gas flow path(s) has/have an inlet and an outlet; the inlet and the outlet each communicate with the exterior of the measuring device; the gas flow path(s) open(s) into the container in which it/they is/are formed; and a gas flowing in the gas flow path(s) contacts the droplet filled in the container.
    Type: Application
    Filed: October 2, 2020
    Publication date: October 13, 2022
    Applicant: KANAGAWA INSTITUTE OF INDUSTRIAL SCIENCE AND TECHNOLOGY
    Inventors: Tetsuya YAMADA, Toshihisa OSAKI, Hisatoshi MIMURA, Hirotaka SUGIURA, Shoji TAKEUCHI
  • Patent number: 11447696
    Abstract: A fluorescent member according to present invention is composed of a sintered body for wavelength conversion containing a matrix containing magnesium oxide and magnesium hydroxide as main components, and phosphor particles dispersed in the matrix. A thermal conductivity of the fluorescent member is preferably 5 W/(m·K) or higher. A fluorescent member having both a satisfactory thermal conductivity and a satisfactory fluorescent property is provided without requiring a high-temperature sintering process (a high-temperature process at a temperature higher than 250° C.). Further, a method for manufacturing such a fluorescent member and a light-emitting apparatus using such a fluorescent member are provided.
    Type: Grant
    Filed: July 22, 2020
    Date of Patent: September 20, 2022
    Assignee: KANAGAWA INSTITUTE OF INDUSTRIAL SCIENCE AND TECHNOLOGY
    Inventors: Junichi Tatami, Emi Takahashi, Takuma Takahashi
  • Publication number: 20220228113
    Abstract: Provided is a hair follicle germ capable of forming a hair shaft-like structure in vitro simply and within a short period of time. A method of producing a hair follicle germ includes: inoculating epithelial cells and mesenchymal cells; maintaining the epithelial cells and the mesenchymal cells in a culture solution in which (a) laminin and entactin, and/or (b) type IV collagen is dispersed; and co-culturing the epithelial cells and the mesenchymal cells in a culture solution to form a hair follicle germ.
    Type: Application
    Filed: August 7, 2019
    Publication date: July 21, 2022
    Applicants: National University Corporation Yokohama National University, Kanagawa Institute of Industrial Science and Technology
    Inventors: Junji Fukuda, Tatsuto Kageyama, Akihiro Shimizu, Rikuma Nakajima, Riki Anakama
  • Patent number: 11276871
    Abstract: To provide an electrolyte membrane that exhibits high proton conductivity even at low humidity, the electrolyte membrane includes a composite membrane including: a microporous polyolefin membrane that has an average pore diameter of 1 to 1000 nm and a porosity of 50 to 90% and that can be impregnated with a solvent having a surface free energy of 28 mJ/m2 or more, and an electrolyte containing a perfluorosulfonic acid polymer having an EW of 250 to 850 loaded into the pores of the microporous polyolefin membrane, wherein the membrane thickness of the composite membrane is 1 to 20 ?m.
    Type: Grant
    Filed: May 31, 2017
    Date of Patent: March 15, 2022
    Assignees: TOKYO INSTITUTE OF TECHNOLOGY, TEIJIN LIMITED, KANAGAWA INSTITUTE OF INDUSTRIAL SCIENCE AND TECHNOLOGY
    Inventors: Takeo Yamaguchi, Yuhei Oshiba, Hidenori Ohashi, Jin Tomatsu, Koji Furuya, Takao Ohno, Mami Nanbu
  • Publication number: 20220041983
    Abstract: Provided are a hair follicle germ having excellent hair growth-related properties, a method of producing a hair follicle germ, and a method of activating cells contained in a hair follicle germ. The hair follicle germ includes: epithelial cells; mesenchymal cells; and mesenchymal stem cells. The method of producing a hair follicle germ includes co-culturing epithelial cells, mesenchymal cells, and mesenchymal stem cells to form a hair follicle germ.
    Type: Application
    Filed: October 15, 2019
    Publication date: February 10, 2022
    Applicants: National University Corporation Yokohama National University, Kanagawa Institute of Industrial Science and Technology
    Inventors: Junji Fukuda, Tatsuto Kageyama, Yoshiki Tate
  • Publication number: 20210282795
    Abstract: A medical gripping device includes a housing, a gripping mechanism at one end of the housing, an operation unit, and a reaction force actuator and a gripping actuator installed in the housing. The operation unit is operated by a gripping operation of an operator, and the reaction force actuator applies an operation reaction force to the operation unit. The gripping actuator causes the gripping mechanism to perform a gripping operation. A control unit controls a force and a position that are output by the gripping actuator in an operation of the gripping mechanism in accordance with an operation with respect to the operation unit, and controls a force and a position that are output by the reaction force actuator in an operation of applying the operation reaction force to the operation unit in accordance with a reaction from a gripped object with respect to the gripping mechanism.
    Type: Application
    Filed: June 7, 2019
    Publication date: September 16, 2021
    Applicants: KANAGAWA INSTITUTE OF INDUSTRIAL SCIENCE AND TECHNOLOGY, KEIO UNIVERSITY
    Inventors: Tomoyuki SHIMONO, Hikaru SASAKI, Kouhei OHNISHI, Shunsuke SHIBAO, Takahiro MIZOGUCHI, Takuya MATSUNAGA, Eriko ABIKO, Masaaki NISHIMOTO, Mika AOKI
  • Patent number: 11111433
    Abstract: Provided are a transparent fluorescent sialon ceramic having fluorescence and optical transparency; and a method of producing the same. Such a transparent fluorescent sialon ceramic includes a sialon phosphor which contains a matrix formed of a silicon nitride compound represented by the formula Mx(Si,Al)y(N,O)z (here, M represents at least one selected from the group consisting of Li, alkaline earth metals, and rare earth metals, 0?x/z<3, and 0<y/z<1) and a luminescent center element.
    Type: Grant
    Filed: March 6, 2015
    Date of Patent: September 7, 2021
    Assignees: NATIONAL UNIVERSITY CORPORATION YOKOHAMA NATIONAL UNIVERSITY, KANAGAWA INSTITUTE OF INDUSTRIAL SCIENCE AND TECHNOLOGY
    Inventors: Takuma Takahashi, Junichi Tatami, Yuki Sano, Takehiko Tanaka, Masahiro Yokouchi
  • Patent number: 11078416
    Abstract: Provided are a transparent fluorescent sialon ceramic having fluorescence and optical transparency; and a method of producing the same. Such a transparent fluorescent sialon ceramic includes a sialon phosphor which contains a matrix formed of a silicon nitride compound represented by the formula Mx(Si,Al)y(N,O)z (here, M represents at least one selected from the group consisting of Li, alkaline earth metals, and rare earth metals, 0?x/z<3, and 0<y/z<1) and a luminescent center element.
    Type: Grant
    Filed: March 6, 2015
    Date of Patent: August 3, 2021
    Assignees: NATIONAL UNIVERSITY CORPORATION YOKOHAMA NATIONAL UNIVERSITY, KANAGAWA INSTITUTE OF INDUSTRIAL SCIENCE AND TECHNOLOGY
    Inventors: Takuma Takahashi, Junichi Tatami, Yuki Sano, Takehiko Tanaka, Masahiro Yokouchi
  • Publication number: 20210163918
    Abstract: Provided are a cell-containing hydrogel body and a method of producing the same, which enable simple and effective control of the size of a boundary surface for an interaction between cells. The method of producing a cell-containing hydrogel body includes: forming, under a gas phase, a first hydrogel droplet on a surface of a substrate, the first hydrogel droplet containing first cells being dispersed therein and a first hydrogel polymer; forming, under a gas phase, a second hydrogel droplet on the surface, the second hydrogel droplet containing second cells being dispersed therein and a second hydrogel polymer, the second hydrogel droplet being combined with the first hydrogel droplet; and forming, under a gas phase, a cell-containing hydrogel body on the surface by gelling a hydrogel droplet-combined body including a first droplet portion derived from the first hydrogel droplet and a second droplet portion derived from the second hydrogel droplet.
    Type: Application
    Filed: April 16, 2019
    Publication date: June 3, 2021
    Applicants: National University Corporation Yokohama National University, Kanagawa Institute of Industrial Science and Technology
    Inventors: Junji Fukuda, Tatsuto Kageyama
  • Patent number: 10982140
    Abstract: A nitride phosphor particle dispersion-type sialon ceramic of the present invention includes a matrix formed of a sialon-based compound; and at least one nitride phosphor which is dispersed in the matrix and contains a luminescence center element.
    Type: Grant
    Filed: August 25, 2017
    Date of Patent: April 20, 2021
    Assignees: KANAGAWA INSTITUTE OF INDUSTRIAL SCIENCE AND TECHNOLOGY, NATIONAL UNIVERSITY CORPORATION YOKOHAMA NATIONAL UNIVERSITY
    Inventors: Takuma Takahashi, Junichi Tatami, Ippei Kokubun, Masahiro Yokouchi
  • Publication number: 20210107134
    Abstract: A haptic transmission system includes a master device and a slave device. The master device controls position and force in an operation of the master device based on information acquired from the operation of the master device and information relating to a response of the slave device, and compensates for a communication delay in a communication path with respect to the control of force. The slave device controls speed and force in an operation of the slave device based on information acquired from the operation of the slave device and information relating to control from the master device.
    Type: Application
    Filed: March 7, 2019
    Publication date: April 15, 2021
    Applicants: KANAGAWA INSTITUTE OF INDUSTRIAL SCIENCE AND TECHNOLOGY, KEIO UNIVERSITY
    Inventors: Tomoyuki SHIMONO, Takahiro MIZOGUCHI, Kouhei OHNISHI, Tetsuya TASHIRO
  • Publication number: 20210079345
    Abstract: Provided are a method and kit for growth of hair follicle epithelial stem cells on a large scale while maintaining their hair regeneration ability. The culture method for hair follicle epithelial stem cells includes: an accumulating step of forming an accumulation of hair follicle epithelial stem cells by inoculating a cell culture vessel with the hair follicle epithelial stem cells; a mixing step of producing a mixture of an extracellular matrix component and the accumulation of the hair follicle epithelial stem cells by adding the extracellular matrix component to the accumulation of the hair follicle epithelial stem cells; and a culturing step of culturing the hair follicle epithelial stem cells by adding a medium to the mixture. The culture kit for hair follicle epithelial stem cells includes: a cell culture vessel formed of a material having oxygen permeability; an extracellular matrix component; and a medium.
    Type: Application
    Filed: February 4, 2019
    Publication date: March 18, 2021
    Applicants: National University Corporation Yokohama National University, Kanagawa Institute of Industrial Science and Technology
    Inventors: Junji Fukuda, Tatsuto Kageyama, Sugi Hirano
  • Patent number: 10865373
    Abstract: The present invention provides a method for manufacturing a regular and high-density regenerated hair follicle primordium aggregation similar to the hair follicle tissue of a mammal in a simple manner. A regenerated hair follicle primordium aggregation manufacturing method of the present invention includes a step of forming hair follicle primordia by inoculating a microwell plate, which includes regularly arranged microwell portions, with mesenchymal cells and epithelial cells and culturing a mixture of the cells while supplying oxygen thereto.
    Type: Grant
    Filed: October 26, 2016
    Date of Patent: December 15, 2020
    Assignees: National University Corporation Yokohama National University, Kanagawa Institute of Industrial Science and Technology
    Inventors: Junji Fukuda, Tatsuto Kageyama, Chisa Yoshimura, Kisaki Onishi
  • Publication number: 20200346444
    Abstract: Disclosed are a separator for lipid bilayer membrane formation capable of forming a lipid bilayer membrane with excellent properties, wherein the separator for lipid bilayer membrane formation has sufficient mechanical strength and can be easily manufactured in a large scale by using a general-purpose machine without need of using an expensive machine, and a method of producing the separator. The separator for lipid bilayer membrane formation includes a thin film having one or more through holes and made of a resin capable of being wet-etched, and reinforcing layers covering both surfaces of the thin film and made of a resin capable of being wet-etched. The reinforcing layers cover the whole area of the thin film, except for the through holes and the peripheries thereof, and each through hole has a tapered cross-sectional shape.
    Type: Application
    Filed: January 15, 2019
    Publication date: November 5, 2020
    Applicants: KANAGAWA INSTITUTE OF INDUSTRIAL SCIENCE AND TECHNOLOGY, TORAY ENGINEERING CO., LTD.
    Inventors: Toshihisa OSAKI, Masatoshi HAYAKAWA, Koki KAMIYA, Miharu KANEKO, Hideo UEHARA, Katsufumi ARAKI, Ayumi KONDA, Hajime HIRATA, Toshiyuki URA
  • Publication number: 20200208106
    Abstract: Provided is a manufacturing method for a plurality of regenerated hair follicle germs, including a step including simultaneously inoculating a microwell plate including regularly arranged microwell portions with mesenchymal cells and epithelial cells, and co-culturing the mesenchymal cells and the epithelial cells using a medium containing a fibroblast growth factor while supplying oxygen to the mesenchymal cells and the epithelial cells from at least an upper surface and a bottom surface of the microwell plate, to thereby form hair follicle germs in the microwell portions, the microwell plate being formed of a material having oxygen permeability. Also provided is a kit for hair regeneration, including: a microwell plate including regularly arranged microwell portions; and a fibroblast growth factor, wherein the microwell plate is formed of a material having oxygen permeability.
    Type: Application
    Filed: August 16, 2018
    Publication date: July 2, 2020
    Applicants: National University Corporation Yokohama National University, Kanagawa Institute of Industrial Science and Technology
    Inventors: Junji Fukuda, Tatsuto Kageyama, Akihiro Shimizu
  • Publication number: 20190267655
    Abstract: To provide an electrolyte membrane that exhibits high proton conductivity even at low humidity, the electrolyte membrane includes a composite membrane including: a microporous polyolefin membrane that has an average pore diameter of 1 to 1000 nm and a porosity of 50 to 90% and that can be impregnated with a solvent having a surface free energy of 28 mJ/m2 or more, and an electrolyte containing a perfluorosulfonic acid polymer having an EW of 250 to 850 loaded into the pores of the microporous polyolefin membrane, wherein the membrane thickness of the composite membrane is 1 to 20 ?m.
    Type: Application
    Filed: May 31, 2017
    Publication date: August 29, 2019
    Applicants: TOKYO INSTITUTE OF TECHNOLOGY, TEIJIN LIMITED, KANAGAWA INSTITUTE OF INDUSTRIAL SCIENCE AND TECHNOLOGY
    Inventors: Takeo YAMAGUCHI, Yuhei OSHIBA, Hidenori OHASHI, Jin TOMATSU, Koji FURUYA, Takao OHNO, Mami NANBU