Abstract: A disease treatment is provided by controlling the expression of a protein induced by a heat shock factor. The novel compound benzo-1,3-dioxole provides an inhibitor of HSF activity or an inhibitor of inducing the production of a protein regulated by HSF, which inhibits the activity of a heat shock factor, a transcriptional regulatory factor, thereby in turn inhibiting transcription of a structural gene having a heat shock element sequenc in the gene region for transcriptional regulation into RNA, and thus inhibiting translation of the gene into a protein, and resulting in inhibition of inducing production of RNA or protein encoded by the gene. It also provides a drug for treating or preventing cancer through thermotherapy and a drug for treating or preventing stress diseases such as depression.

Abstract: A diagnostic drug and a diagnostic kit for autoimmune diseases including at least one of a polypeptide selected from an HMG-1 family, a polypeptide selected from an HMG-2 family, a fragment thereof which is reactable with an antibody of an autoimmune disease patient, and a method for detecting an antibody of an autoimmune disease patient using the same are provided.

Abstract: A vehicular lamp and method for manufacturing including the steps of: providing a lamp body that has been formed from a resin composition obtained by incorporating 0.1 to 5 parts by weight of an antistatic agent in 100 parts by weight of a rubber-reinforced styrene resin; pressing a heated hot plate against the lamp body, thereby melting a portion of the lamp body; and adhering the melted portion of the lamp body to a lamp lens under pressure, thereby bonding the lamp body to the lamp lens.