Abstract: One or more embodiments of the present invention are to provide a new means of improving the productivity of a target protein. The present inventors have identified a novel protein consisting of the amino acid sequence set forth in SEQ ID NO: 2 through an exhaustive analysis of the nucleotide sequence of chromosomal DNA of a yeast belonging to the genus Komagataella. Activation of a gene encoding the novel protein provides a cell having an improved productivity of a target protein.
Type:
Grant
Filed:
September 25, 2020
Date of Patent:
November 1, 2022
Assignees:
NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITY, KANEKA CORPORATION
Abstract: A resin composition containing (A) an organopolysiloxane having a glycidyloxy group, and (B) at least one selected from the group consisting of a triarylalkoxysilane, a diaryldialkoxysilane, a hydrolysate thereof and a partially hydrolyzed/condensed product thereof is provided. The resin composition may further contain (C) a ?-dicarbonyl compound. The resin composition may further contain (D) an organic compound having one or more of an epoxy group, an oxetanyl group and a vinyl ether group. The resin composition may be mixed with (E) an organoaluminum compound and/or organotitanium compound and be cured.
Abstract: Highly proliferative mesenchymal stem cells (MSCs) may be useful for the large-scale and rapid production of a cell preparation, and a cell population may include the mesenchymal stem cells. A cell population may include mesenchymal stem cells derived from a fetal appendage, wherein, in the cell population, the proportion of CD105+ mesenchymal stem cells is 50% or more, the proportion of CD200+ mesenchymal stem cells is less than 10%, and the proportion of CD106+ mesenchymal stem cells is less than 5%.
Type:
Application
Filed:
June 27, 2022
Publication date:
October 27, 2022
Applicant:
KANEKA CORPORATION
Inventors:
Masahiro Hayashi, Yuta Kita, Nobuyoshi Umeda
Abstract: An objective of the present invention is to provide a production method that enables PHA (e.g. PHA powder) to be produced with high productivity. The above is achieved by providing: a method for producing a polyhydroxyalkanoate, including the steps of (a) preparing an aqueous suspension that contains a polyhydroxyalkanoate and an alkylene oxide-based dispersing agent and has a pH of not more than 7 and (b) spray-drying the aqueous suspension prepared in the step (a); and the like.
Type:
Application
Filed:
October 29, 2020
Publication date:
October 27, 2022
Applicant:
KANEKA CORPORATION
Inventors:
Tomoya NISHINAKA, Naoki DEGUCHI, Jun HATTORI, Masaru HIRANO
Abstract: A photoelectric conversion element for detecting the spot size of incident light, including a photoelectric conversion substrate provided with two main surfaces, and multiple first sensitivity sections and second sensitivity sections arranged in a prescribed direction. When sensitivity regions on the respective main surfaces of the multiple first sensitivity sections are defined as first sensitivity regions, and sensitivity regions that appear on the main surfaces of the second sensitivity sections are defined as second sensitivity regions, each of the first sensitivity regions receives at least a part of light incident on the main surfaces, and has a pattern in which, in accordance with enlargement of an irradiation region irradiated with incident light on the main surface, the proportion of the first sensitivity regions in the irradiation region with respect to the first sensitivity regions other than those in the irradiation region and the second sensitivity regions is decreased.
Abstract: A light therapy diagnostic device comprising a shaft, and an optical waveguide disposed in a lumen of the shaft and being movable forward and backward in a longitudinal direction, wherein: the optical waveguide guides a first light and a second light; the shaft has a lateral emission window which allows the first light and the second light to be emitted toward a lateral direction and a distal emission window which allows the first light to be emitted toward a distal direction; a first mirror is provided on a distal end part of the optical waveguide and reflects the first light toward a lateral direction of the shaft; and a second mirror is provided on an inner surface of the shaft, located distal to a distal end of the lateral emission window, and reflects the first light reflected by the first mirror toward a distal direction of the shaft.
Abstract: The method for producing a balloon catheter comprises a tubular object preparing step to prepare a tubular object having a space extending in the distal-proximal direction, a balloon preparing step to prepare a balloon, a balloon placement step to place the balloon in the tubular object and inflate the balloon, and a balloon deflating step to deflate the balloon and form a wing-shaped portion, wherein a projecting portion is placed on within a mean circle C1 centered at a center P1 of the tubular object, and a radius of the mean circle C1 is an average value of a shortest distance D1 from the center P1 of the tubular object to an inside surface P2 of the tubular object and a longest distance D2 from the center P1 of the tubular object to the inside surface P3 of the tubular object on a cross-section in the balloon placement step.
Abstract: The invention relates to a nanocomposite coating system that exhibits superior barrier properties for reducing the ingress of unwanted guest species such as moisture (e.g., water vapor) and a facile method for preparing the same nanocoating system on an industrial scale. The current coating materials are able to reduce the overall ingress of unwanted guest species in a substantial improvement over the prior art.
Type:
Application
Filed:
October 16, 2020
Publication date:
October 13, 2022
Applicants:
THE UNIVERSITY OF CONNECTICUT, KANEKA AMERICAS HOLDING, KANEKA CORPORATION
Inventors:
LUYI SUN, ANNA MARIE LACHANCE, TIANLEI ZHOU, YOUNG LIM
Abstract: An object of the present invention is to provide a manufacturing apparatus for a solar cell group that is likely to be recognized as having a good color balance when viewed by humans. The manufacturing apparatus for a solar cell group of the present invention includes an arrangement operation unit (12) that arranges solar cells and a machine learning unit (20). The solar cell group is formed by planarly arranging the solar cells. The solar cells have a light receiving surface and include an antireflection material on the light receiving surface side. Some of the solar cells have a variation in color element due to a difference in thickness of the antireflection material or a difference in refractive index of the antireflection material. The machine learning unit (20) performs machine learning using a correlation between an arrangement of the solar cells and a determination result by humans on color balance of the solar cell group as training data.
Abstract: A solar cell module, which is easily coordinated with the color of an exterior member at the installation position, comprises a solar cell; a light receiving side sealing material and a light receiving side protection member laminated and disposed in this order on a light receiving side with reference to the solar cell; and a back-side sealing material and a back-side protection member laminated and arranged in this order on a back side on the opposite side from the light receiving side. A value computed from a measured value of the color of reflected light combining positive reflected light and diffused reflected light which are based on light that has become incident on an object to be measured, and a measured value of the color only of the diffused reflected light based on the light that has become incident on the object to be measured, satisfies a specific condition.
Abstract: Provided is a transformed microorganism that has a polyhydroxyalkanoate synthase gene and in which expression of an A1386 gene and/or an A2405 gene is reduced. In the transformed microorganism, expression of a minC gene and a minD gene may be enhanced. Also provided is a method of producing a PHA, the method including the step of culturing the transformed microorganism in the presence of a carbon source.
Type:
Application
Filed:
August 4, 2020
Publication date:
October 6, 2022
Applicant:
KANEKA CORPORATION
Inventors:
Yoshihiro MOURI, Hisashi ARIKAWA, Shunsuke SATO
Abstract: Provided are poly(3-hydroxyalkanoate) foam particles, which can give a foam molded article having good surface aspects and a low shrinkage ratio of a molding, and the foam molded article. The poly(3-hydroxyalkanoate) foam particles have at least two melting peaks on a DSC curve obtained by differential scanning calorimetry and in which a melting calorie (X) on a high temperature side is 0.1 to 20 J/g, a gel fraction (Y) is 20 to 75% by weight, and the melting calorie (X) and the gel fraction (Y) satisfy Formula: X+Y?30.
Abstract: An object of the present invention is to provide a method for producing PHA capable of providing PHA (for example, a PHA powder) having excellent thermal stability with high productivity. The present invention is a method for producing polyhydroxyalkanoic acid, the method including a step (a) and a step (b) below: step (a) of preparing an aqueous suspension liquid containing polyhydroxyalkanoic acid and polyvinyl alcohol and having a pH of 7 or less; and step (b) of spray-drying the aqueous suspension liquid prepared in the step (a).
Abstract: A building material-integrated solar cell module (5) includes a solar cell panel (11), a cushioning member (13) disposed at a back side of the solar cell panel (11), a base plate (9) formed of an incombustible material and supporting the cushioning member (13), and a cable (35) drawn from the back side of the solar cell panel (11) and wired on a front side of the base plate (9).
Abstract: Disclosed is a balloon catheter that can prevent or reduce axial rotation and circumferential shift of the elongate body while ensuring good passage of the balloon in the blood vessel. The balloon catheter (100) has a shaft (110); a balloon (120); an elongate body (180) extending along the shaft (110) and having a body tissue contacting part at its distal end part; and an elongate body lumen (130), the elongate body lumen (130) having a first engagement part (131) so that axial rotation angle of the elongate body (180) is 0° to 60°, and the first engagement part (131) being located between the distal end (130d) of the elongate body lumen (130) and a position 30 cm from the distal end of the elongate body lumen (130) toward the proximal side.
Abstract: A method for inhibiting renal hypofunction in a non-human animal includes administering cat-derived erythropoietin to the non-human animal. The non-human animal may have renal hypofunction. The non-human animal may have chronic kidney disease and the renal hypofunction may be caused by the chronic kidney disease. The cat-derived erythropoietin may be administered repeatedly at a time interval of 7 to 30 days.
Abstract: Provided is a production method capable of efficiently producing a reduced coenzyme Q10 Form II crystal. The method for producing a reduced coenzyme Q10 Form II crystal includes: adding a reduced coenzyme Q10 Form II crystal as a seed crystal to a solution with a temperature of 32° C. to 43° C., the solution containing fa) at least one organic solvent selected from the group consisting of an alcohol, a hydrocarbon, an aliphatic acid ester and a nitrogen compound, and (b) reduced coenzyme Q10, to prepare a mixture, and precipitating the reduced coenzyme Q10 from the mixture, in the form of the reduced coenzyme Q10 Form II crystal.
Abstract: The present application provides: a transformed microorganism for producing a PHA copolymer containing 3HH monomer unit at a higher composition ratio, specifically, a transformed microorganism comprising a PHA synthase gene capable of synthesizing a PHA copolymer containing 3HH monomer unit and a gene encoding a protein having (R)-specific enoyl-CoA hydratase activity, characterized in that, in the transformed microorganism, the expression of a gene encoding at least one ?-ketothiolase enzyme having thiolysis activity for ?-keto-(C6) acyl-CoA (i.e., ?-ketohexanoyl-CoA) is inhibited, thereby losing or reducing the enzyme activity; and a method for producing a PHA copolymer containing 3HH monomer unit, comprising a step of culturing the transformed microorganism.
Abstract: A nonaqueous electrolyte secondary battery which is provided with a positive electrode, a negative electrode and a nonaqueous electrolyte. The positive electrode contains: a positive electrode active material and a compound having a cobalt content of 30% by weight or more. The weight A of the compound and the total weight B of the positive electrode active material satisfy 0.01?A/(A+B)?0.15. The negative electrode contains a negative electrode active material. The nonaqueous electrolyte contains propylene carbonate and diethyl carbonate as nonaqueous solvents; the total amount of the propylene carbonate and the diethyl carbonate is 70% by volume or more relative to 100% by volume of the nonaqueous solvents; and the volume ratio of the propylene carbonate to the diethyl carbonate is within the range of from 1:1 to 1:19.
Abstract: Hybrid organic/inorganic coating compositions of nanometer thickness are described, where the organic layer is a clay-containing layer comprising a clay and a hydrophilic polymer and the inorganic layer is a metal-containing layer comprising a metal with a refractive index greater than 1.5, where the coating compositions allow for the generation and tenability of iridescent color through control of the coat thickness.
Type:
Grant
Filed:
August 17, 2018
Date of Patent:
September 20, 2022
Assignees:
Kaneka Corporation, The University of Connecticut
Inventors:
Luyi Sun, Jingjing Liu, Songshan Zheng, Thomas D'Auria, Young Hoon Lim, Tianlei Zhou, Masaya Kotaki