Abstract: Provided is a method of producing a polyhydroxyalkanoate copolymer mixture. The method includes the step of culturing a microorganism that produces the polyhydroxyalkanoate copolymer mixture. The mixture contains: a fraction (I) containing a polyhydroxyalkanoate copolymer having a 3-hydroxybutyrate structural unit and a 3-hydroxyhexanoate structural unit, the fraction (I) having an average 3-hydroxyhexanoate unit ratio of 20 mol % or more; and a fraction (II) containing a polyhydroxyalkanoate having a 3-hydroxybutyrate structural unit, the fraction (II) having an average 3-hydroxyhexanoate unit ratio of 0 to 15 mol %. The polyhydroxyalkanoate copolymer mixture has an average 3-hydroxyhexanoate unit ratio of 22 mol % or less.

Abstract: The pluripotent stem cell culture environment is appropriately controlled to improve production efficiency, and to suppress cell death when passaging pluripotent stem cells from suspension culture. Pluripotent stem cells subjected to suspension culture in a perfusion mode under appropriate medium perfusion conditions are passaged in the subsequent culture step, thereby improving passage efficiency. By strictly controlling the amount of medium perfused in line with the progress of culture of pluripotent stem cells and/or adjusting the amount of carbon dioxide gas supplied in line with the progress of culture of pluripotent stem cells, culture efficiency and productivity can be remarkably improved.

Abstract: A catheter handle (1) includes handle body (2), and rotary member (3) being free to rotate with respect to the handle body (2) and connected to the wire. The handle body (2), in a planar view from a rotation axis direction of the rotary member (3), has second space (12) for the conductive wire is located from more distal side to more proximal side than first space (11) for the rotary member (3). The operating part (4) of the rotary member (3) is disposed on one side, and the second space (12) is disposed on another side, in the width direction of the handle (1). Length L1 from the center of the rotation axis to the rotary member (3) on the one side is longer than length L2 from the center of the rotation axis to the rotary member (3) on the another side.

Abstract: Provided is a method for producing a balloon catheter having a high-quality balloon, the method enabling an entire mold to be uniformly heated. A method for producing a balloon catheter having a shaft extending in a distal-proximal direction and a balloon provided on a distal side of the shaft, the method comprising: a tubular body placement step of placing a resin tubular body (10) inside a mold (20); a mold placement step of placing the mold (20) inside a heating jacket (30); a heating start step of starting heating the heating jacket (30); an elongation start step of starting elongating the resin tubular body (10) in a lengthwise direction thereof an elongation end step of ending elongating the resin tubular body (10); and a heating end step of ending heating the heating jacket (30), wherein the heating end step is performed before the elongation end step.

Abstract: The present application relates to a method for producing a catheter tube. The method including sucking gas from a second end 43 of a tubular body 40 while introducing pressurized gas into a lumen 41 of the tubular body 40 from a first end 42 of the tubular body 40, so that an internal pressure is applied to the lumen 41 of the tubular body 40 by introducing the pressurized gas, and the tubular body 40 is delivered in a direction from the first end 42 to the second end 43 by sucking the gas from the second end 43 of the tubular body 40.

Abstract: An object of the present invention is to provide a method for producing recycled water, according to which when recycled water is prepared from waste water, chemical cleaning of a membrane can be significantly reduced and fouling of the membrane can be eliminated by substantially only washing with water. The above object is achieved by providing a method for producing recycled water, the method including the following steps (A) to (D) of: (A) subjecting waste water to an anaerobic treatment and an aerobic treatment which are carried out by microorganisms, the waste water having been discharged during a production process of a PHA; (B) subjecting treated water obtained in step (A) to pretreatment filtration performed by a membrane bioreactor method; (C) subjecting the treated water obtained in step (B) to an alkali treatment; and (D) filtering, through an ion removal membrane, the treated water obtained in step (C).

Abstract: A method for preparing a cell sheet having a durable strength in practical use with good reproducibility within a period of time as short as possible, regardless of a culture medium additive or a type of culture vessel to be used is provided. The method for producing a cell sheet comprises a step of culturing mesenchymal stem cells in a medium containing an ascorbic acid species at 0.3 mM or higher and a ROCK (Rho-associated coiled-coil forming kinase) inhibitor to prepare mesenchymal stem cells in a sheet-like form in a culture vessel, wherein the ascorbic acid species is a water-soluble ascorbic acid derivative or a mixture of a water-soluble ascorbic acid derivative and ascorbic acid.

Abstract: The objective of the present invention is to provide a method for visualizing an aggregate of aggregating proteins in an environment similar to in vivo conditions. More specifically, the present invention relates to a method for collecting an aggregating protein-containing solution by allowing an aggregating protein-containing solution to pass through a filtration filter through which a solution for accelerating and visualizing protein aggregation has passed; a method for visualizing an aggregate of aggregating proteins comprising visualizing an aggregate of aggregating proteins in the aggregating protein-containing solution collected by the collecting method; and a method of forming an aggregate of labeled aggregating proteins of interest in a medium or culture supernatant from which an aggregation inhibitor of 40 kDa or higher has been removed, so as to visualize aggregation.

Abstract: An object of the present invention is to provide a method for manufacturing an injection-molded product of a resin composition containing a P3HA-based resin, capable of performing stable continuous production without generating flash. To achieve the object, provided is a method for manufacturing an injection-molded product by using a mold apparatus for a resin composition containing a P3HA-based resin, the P3HA-based resin being a copolymer containing at least one kind of copolymer of a 3HB unit and another hydroxyalkanoate unit, a parting line that is in contact with a cavity inside a mold included in the mold apparatus having a maximum width of not more than 30 ?m, a vent portion being provided at a specific position inside the mold, the vent portion having an opening portion with a maximum width of 1 ?m to 50 ?m.

Abstract: The objective of the present invention is to provide a container for easily and efficiently purifying a target biomolecule from a cell culture liquid or a body fluid and a method for purifying a target biomolecule by using the container. The purification container for a target biomolecule from a cell culture liquid or a body fluid is characterized by comprising an inlet, a filter and an outlet, and further comprising an adsorbent for adsorbing an impurity and/or an aggregating agent for aggregating an impurity, wherein the filter captures the impurity adsorbed on the adsorbent and/or the impurity aggregated by the aggregating agent.

Abstract: Expandable resin particles that have a reduced VOC content, a method of producing the expandable resin particles, and a foamed molded product that has reduced VOC emission are provided. The expandable resin particles contain a base material resin containing, as a structural unit, a styrene unit and an acrylonitrile unit and an expanding agent. The expandable resin particles have a styrene content and an ethylbenzene content each of which is not more than a specific amount.

Abstract: A polyamic acid that is a polyaddition reaction product of a diamine and a tetracarboxylic dianhydrides, according to one or more embodiments of the present invention. The polyamic acid contains 2?-bistrifluoromethylbenzidine as a diamine component in addition to 3,3?,4,4?-biphenyltetracarboxylic dianhydride and 9,9?-(3,4?-dicarboxyphenyl)fluorenic dianhydride as tetracarboxylic dianhydride components. The polyamic acid may include 9,9?-(3,4?-dicarboxyphenyl)fluorenic dianhydride in an amount ranging from 0.5 mol % or more to 10 mol % or less based on total amount of the tetracarboxylic anhydride.

Abstract: The present disclosure provides a low dielectric resin composition having good melt processability and excellent low dielectric characteristics in a high frequency band as compared to low dielectric materials such as liquid crystal polymers. A molded article and a film, each of which is formed from the low dielectric resin composition, a multilayer film obtained by superposing a metal foil on at least one main surface of the film, and a flexible printed wiring board which includes the film are also provided. The present disclosure includes, as a low dielectric resin composition, a resin composition which contains (A) a liquid crystal polymer and (B) a graft-modified polyolefin having a polar group. The low dielectric resin composition has a dielectric constant of 2.80 or less at a frequency of 10 GHz and a dielectric loss tangent of 0.0025 or less at a frequency of 10 GHz.

Abstract: A solar cell module comprises cell groups each containing solar cells, and each solar cell includes photoelectric converters, N number of which being connected in series, and first, second and third terminals. When the first terminal on one end of a first cell group has a reference potential, the second terminal on the other end of the mth cell group is connected to the first terminal on one end of another cell group, and N number of the third terminals of the mth cell group are respectively connected to N number of the first terminals of an m+1th cell group. The difference in potential between the second terminal on the other end of the mth cell group and the first terminal on one end of the other cell group is 10% or less of the difference in potential between the second and first terminals of the mth cell group.

Abstract: It is an object of the present disclosure to provide a method for producing a reduced coenzyme Q10 Form II crystal or a crystalline solid thereof, which is capable of stably producing a reduced coenzyme Q10 Form II crystal or a crystalline solid thereof.

Abstract: It is an object of the present disclosure to provide a method for producing a reduced coenzyme Q10 Form II crystal or a crystalline solid thereof, which is excellent in the filterability of a slurry containing a reduced coenzyme Q10 Form II crystal. The present embodiment is a method for producing a reduced coenzyme Q10 Form II crystal or a crystalline solid thereof, including: adding a reduced coenzyme Q10 Form II crystal as a seed crystal to a mixed solution containing an alcohol and a reduced coenzyme Q10; and precipitating a reduced coenzyme Q10 Form II crystal in the mixed solution after adding the seed crystal, wherein a change rate of formazin turbidity (FTU) is maintained at 15 FTU/min or more for 80% or more of a period during which the formazin turbidity (FTU) shifts from 1,000 to 10,000 in the precipitation.

Abstract: A bi-directional medical suturing device includes a first needle; a second needle being disposed distal to the first needle; a first thread control member including a first holding portion being movable between a position where the first holding portion prevents a movement of the first needle and a position where the first holding portion does not prevent the movement of the first needle; and a second thread control member including a second holding portion being located the first holding portion, the second holding portion being movable between a position where the second holding portion prevents a movement of the second needle and a position where the second holding portion does not prevent the movement of the second needle.

Abstract: Provided is a balloon for a balloon catheter that is easy to insert in a body cavity, has good pushability, and can easily incise a stenosis. A balloon for a balloon catheter, having a balloon body (20), the balloon body (20) having a protrusion part (60) that projects outwardly in the radial direction y from its outer surface in the straight tubular part (23) and the proximal tapered part (22), wherein a ratio W1/H1 of a height H1 of the protrusion part (60) and a width W1 of the protrusion part (60) in the straight tubular part (23) is greater than a ratio W2/H2 of a height H2 of the protrusion part (60) and a width W2 of the protrusion part (60) in the proximal tapered part (22).

Abstract: The present invention provides artificial hair, an artificial hair unit, a method of applying artificial hair, and a method of applying an artificial hair unit, in which a fiber bundle does not hang down under its own weight, rises up, and exhibits excellent appearance with extra volume at a root. Also provided is a configuration including a base material, a plurality of fiber bundles, and a fixing thread. In the configuration, the base material may have a first side extending in a first direction. Each of the plurality of fiber bundles includes a plurality of fiber parts and a connecting part, where the connecting part connects a first end side of each of the plurality of fiber parts and extends in a direction different from an extending direction of the plurality of fiber parts, and where the fixing thread attaches a vicinity of the connecting part to the base material.

Abstract: The purpose of the present invention is to adsorb calciprotein particles. An adsorbent for calciprotein particles of the present invention is characterized in that the surface of a water-insoluble carrier is covalently bonded, through a hydrocarbon group, to at least one selected from the group consisting of amino group, carboxyl group, phosphate group, phosphono group, phosphino group, and thiol group.