Patents Assigned to Karlsruher Institut fuer Technologie
-
Patent number: 10494676Abstract: The present invention relates to an in vitro process for the diagnosis of prostate cancer and other tumor types in exosomes obtained from a body fluid which comprises a) concentrating the exosomes and other extracellular vesicles from a body fluid of a patient, b) extraction of total RNA from the exosomes obtained in step a), c) conversion of the RNA obtained in step b) to cDNA, d) amplification of the cDNA obtained in step c) with a polymerase chain reaction whereby primers derived from the AGR2 nucleotide sequence or the complement thereof are used, and e) determining whether in the amplification product variants of the AGR2 gene can be identified.Type: GrantFiled: December 1, 2014Date of Patent: December 3, 2019Assignees: Albert-Ludwigs-Universitaet Freiburg, Karlsruher Institut Für TechnologieInventors: Irina Nazarenko, Andrew Cato, Antje Neeb, Stefanie Bormann, Martin Schoenthaler, Arkadiusz Miernik, Malte Kroenig, Konrad Wilhelm, Benjamin Haenselmann, Simon Hefele
-
Patent number: 10449818Abstract: A rotation damper for a motor vehicle. A flywheel driven via a drive with angular velocity and rotating about an axis of rotation is cardanically mounted via a first bearing element and a second bearing element. The flywheel is rotatably mounted on the first bearing element at the rotational angle and the first bearing element is rotatably mounted on the second bearing element at a first rotational angle of a first axis of the flywheel oriented orthogonally to the axis of rotation, and the second bearing element is rotatably mounted at a second rotational angle of a second axis oriented orthogonally to the first axis. The first bearing element is operationally connected to a shaft drive and the second bearing element can be connected by a means to a wheel carrier of the motor vehicle.Type: GrantFiled: December 12, 2015Date of Patent: October 22, 2019Assignees: AUDI AG, Karlsruher Institut für TechnologieInventors: Tilo Koch, Frank Gauterin, Bastian Scheurich, Michael Frey
-
Patent number: 10399112Abstract: A device for intermittent coating of a substrate moving in a transport direction relative to the device includes a nozzle body comprising two nozzle jaws; an insertion film having a cut-out provided between the two nozzle jaws, wherein the cut-out in the insertion film forms a nozzle slot within the nozzle body, wherein the nozzle slot extends transversely to the transport direction of the substrate and in parallel with the substrate, and wherein the nozzle slot ends in an outlet gap; and a supply channel, wherein the outlet gap is in flow connection with the supply channel via the nozzle slot. A first of the two nozzle jaws is provided with at least two openings which lead into the nozzle slot in series between the supply channel and the outlet gap and which are closed in a fluid-tight manner toward the nozzle slot by at least two elastically deformable elements.Type: GrantFiled: August 7, 2015Date of Patent: September 3, 2019Assignee: KARLSRUHER INSTITUT FUER TECHNOLOGIEInventors: Philip Scharfer, Marcel Schmitt, Wilhelm Schabel, Ralf Diehm
-
Patent number: 10376858Abstract: The present invention relates to a method of producing an oligomer array. The invention comprises the steps of: providing a substrate with a multitude of recesses; introducing a first particle with a first molecule into a recess; releasing the first molecule from the first particle; binding the first molecule to a second molecule to form an oligomer while immobilizing the second molecule in the recess; optionally repeating the steps, wherein at least one of the first particles and/or the first molecules comprises a detectable marker.Type: GrantFiled: April 12, 2018Date of Patent: August 13, 2019Assignee: KARLSRUHER INSTITUT FUER TECHNOLOGIEInventors: Alexander Nesterov-Mueller, Valentina Bykovskaya, Clemens Matthias von Bojnicic-Kninski, Felix Friedrich Loeffler, Roman Popov, Barbara Ridder, Frank Breitling, Daniela Silke Althuon
-
Patent number: 10361487Abstract: Dielectric resonator antennas suitable for use in compact radiofrequency (RF) antennas and devices, and methods of fabrication thereof. Described are dielectric resonator antennas fabricated using polymer-based materials, such as those commonly used in lithographic fabrication of integrated circuits and microsystems. Accordingly, lithographic fabrication techniques can be employed in fabrication. The polymer-based dielectric resonator antennas can be excited using tall metal vertical structures, which are also fabricated using techniques adapted from integrated circuit and microsystems fabrication.Type: GrantFiled: June 11, 2012Date of Patent: July 23, 2019Assignees: University of Saskatchewan, Karlsrúher Institút Für TechnologieInventors: Atabak Rashidian, David Klymyshyn, Mohammadreza Tayfeh Aligodarz, Sven Carsten Achenbach, Martin Wilfried Börner
-
Patent number: 10336613Abstract: A method for carrying out a reaction between at least two reactants in a liquid reaction solution in at least one reaction zone so as to produce a reaction product includes carrying out a reaction continuously in a reaction flow for the at least one reaction zone in an extension of the at least one reaction zone as far as at least one reaction product outlet, introducing each of the at least two reactants over the extension of the at least one reaction zone via inlets in which the reaction flow is introduced, and removing the reaction product via the at least one reaction product outlet.Type: GrantFiled: August 6, 2014Date of Patent: July 2, 2019Assignee: KARLSRUHER INSTITUT FUER TECHNOLOGIEInventors: Manfred Kraut, Roland Dittmeyer, Bhanu Kiran Vankayala
-
Patent number: 10294245Abstract: The present disclosure relates to a compound of general Formula (1) which can be used as an electrode material, an electrode comprising said compound, and a battery cell comprising at least one of said electrode.Type: GrantFiled: February 6, 2017Date of Patent: May 21, 2019Assignee: Karlsruher Institut für TechnologieInventors: Maximilian Fichtner, Zhirong Zhao-Karger, Ping Gao, Zhi Chen, Mario Ruben
-
Patent number: 10276734Abstract: The present invention relates to plasmonic components, more particularly plasmonic waveguides, and to plasmonic photodetectors that can be used in the field of microoptics and nanooptics, more particularly in highly integrated optical communications systems in the infrared range (IR range) as well as in power engineering, e.g. photovoltaics in the visible range. The present invention also specifies a method for producing a plasmonic component, more particularly for photodetection on the basis of internal photoemission.Type: GrantFiled: May 27, 2015Date of Patent: April 30, 2019Assignee: Karlsruher Institut Für TechnologieInventors: Sascha Mühlbrandt, Jürg Leuthold, Manfred Kohl
-
Publication number: 20190111407Abstract: The present invention relates to a reactor for production of synthesis gas that optionally has a fluid-tight connection to a heat exchanger, and to a process for producing synthesis gas, preferably under high pressure.Type: ApplicationFiled: March 21, 2017Publication date: April 18, 2019Applicant: KARLSRUHER INSTITUT FUER TECHNOLOGIEInventors: Peter PFEIFER, Paolo PIERMARTINI, Tim BOELTKEN, Robin DUERRSCHNABEL
-
Patent number: 10247276Abstract: A method for controlling a rotation damper operating according to the gyroscopic principle for a motor vehicle, wherein the rotation damper includes a flywheel, which is driven by a drive and rotating about a rotation axis with an angular velocity ??, which is cardanically mounted via a first bearing element and via a second bearing element, wherein the flywheel is rotatably mounted on a first bearing element and at a rotation angle ?, and the first bearing element is rotatably mounted on a second bearing means about a first axis that is oriented orthogonally to the rotation axis of the flywheel, and the second bearing element is rotatably mounted at a second rotational angle (?).Type: GrantFiled: December 12, 2015Date of Patent: April 2, 2019Assignees: AUDI AG, Karlsruher Institut für TechnologieInventors: Tilo Koch, Bastian Scheurich, Frank Gauterin, Michael Frey
-
Patent number: 10218090Abstract: The disclosed connector can be used to connect superconductive conductors. The connector, which is suitable for electrically connecting at least one first superconductive conductor to at least one second superconductive conductor, includes an electrically conductive base element having a first end portion and a second end portion, and at least one superconductive additional element arranged in the base element extending from the first end portion to the second end portion of the base element.Type: GrantFiled: August 10, 2016Date of Patent: February 26, 2019Assignee: Karlsruher Institut für TechnologieInventors: Walter Fietz, Michael J. Wolf, Reinhard Heller, Klaus-Peter Weiss
-
Patent number: 10199647Abstract: The present invention concerns specific new compounds of formula Li(2?x)Na(x)MO(2?y/2)F(1+y) (where 0?x?0.2 and ?0.6?y?0,8 and M is a transition metal), cathode material comprising the new compounds, batteries and lithium-cells comprising said new compound or cathode material, a process for the production of the new compound and their use.Type: GrantFiled: March 19, 2015Date of Patent: February 5, 2019Assignee: KARLSRUHER INSTITUT FUER TECHNOLOGIEInventors: Ruiyong Chen, Shuhua Ren, Sylvio Indris, Maximillian Fichtner, Horst Hahn
-
Publication number: 20190001607Abstract: The present invention relates to a method for adjusting the elasticity of a work material, to a workpiece produced by this method, and to the use thereof.Type: ApplicationFiled: December 20, 2016Publication date: January 3, 2019Applicant: KARLSRUHER INSTITUT FUER TECHNOLOGIEInventor: Till-Falco BOESE
-
Patent number: 10153071Abstract: The present invention relates to a method and an apparatus for producing superconducting devices and to superconducting devices. The method comprises determining one or more regions of reduced critical current density in the superconducting device and modifying the critical current density in the one or more regions of reduced critical current density, so as to increase the overall critical current or to decrease the overall AC losses of the superconducting device. The modifying comprises modifying the amount and/or distribution of the superconducting material in the one or more regions of reduced critical current density; and/or modifying the chemical composition of the superconducting material in the one or more regions of reduced critical current density; and/or decreasing the cooling temperature in the one or more regions of reduced critical current density. A superconducting device formed according to such method can also be provided.Type: GrantFiled: August 6, 2015Date of Patent: December 11, 2018Assignee: KARLSRUHER INSTITUT FUER TECHNOLOGIEInventors: Victor Manuel Rodriguez Zermeno, Bernhard Holzapfel
-
Publication number: 20180339244Abstract: Methods of controlling at least one multi-column chromatography arrangement for the continuous process of purifying biopharmaceuticals are provided. The methods include introducing a first multi-component mixture into a column of the multi-column chromatography arrangement; detecting at least one multivariate signal by at least one detector; calculating at least one process parameter on the basis of the multivariate signal by at least one data-processing program of a computing unit via application of a chemometric method; and controlling the purification process via control of at least one controllable control element on the basis of the at least one process parameter.Type: ApplicationFiled: November 25, 2016Publication date: November 29, 2018Applicant: Karlsruher Institut für TechnologieInventors: Jürgen Hubbuch, Nina Brestrich, Matthias Rüdt, Laura Rolinger
-
Patent number: 10097257Abstract: In one embodiment, a repeater for wireless communication is provided.Type: GrantFiled: June 19, 2017Date of Patent: October 9, 2018Assignees: Andrew Wireless Systems GmbH, Fraunhofer Gesellschaft zur Förderung der angewandten Forschung e.V., Karlsruher Institut für TechnologieInventors: Oliver Braz, Alfons Dussmann, Luigi Tarlazzi, Thomas Haustein, Thomas Wirth, Dennis Wieruch, Friedrich Jondral, Holger Jäkel
-
Publication number: 20180244121Abstract: A rotation damper for a motor vehicle. A flywheel driven via a drive with angular velocity and rotating about an axis of rotation is cardanically mounted via a first bearing element and a second bearing element. The flywheel is rotatably mounted on the first bearing element at the rotational angle and the first bearing element is rotatably mounted on the second bearing element at a first rotational angle of a first axis of the flywheel oriented orthogonally to the axis of rotation, and the second bearing element is rotatably mounted at a second rotational angle of a second axis oriented orthogonally to the first axis. The first bearing element is operationally connected to a shaft drive and the second bearing element can be connected by a means to a wheel carrier of the motor vehicle.Type: ApplicationFiled: December 12, 2015Publication date: August 30, 2018Applicants: AUDI AG, Karlsruher Institut für TechnologieInventors: Tilo KOCH, Frank GAUTERIN, Bastian SCHEURICH, Michael FREY
-
Publication number: 20180229204Abstract: The present invention relates to a method of producing an oligomer array. The invention comprises the steps of: providing a substrate with a multitude of recesses; introducing a first particle with a first molecule into a recess; releasing the first molecule from the first particle; binding the first molecule to a second molecule to form an oligomer while immobilizing the second molecule in the recess; optionally repeating the steps, wherein at least one of the first particles and/or the first molecules comprises a detectable marker.Type: ApplicationFiled: April 12, 2018Publication date: August 16, 2018Applicant: Karlsruher Institut fuer TechnologieInventors: Alexander Nesterov-Mueller, Valentina Bykovskaya, Clemens Matthias von Bojnicic-Kninski, Felix Friedrich Loeffler, Roman Popov, Barbara Ridder, Frank Breitling, Daniela Silke Althuon
-
Publication number: 20180226177Abstract: Methods and devices for producing a superconductive conductor are disclosed. The method includes providing a plurality of conductive strips by means of a strip provision device, applying liquid soldering agent onto the plurality of conductive strips, stacking the conductive strips wetted with soldering agent, and forming a superconductive body by machining the strip stack.Type: ApplicationFiled: August 10, 2016Publication date: August 9, 2018Applicant: Karlsruher Institut für TechnologieInventors: Walter Fietz, Michael J. Wolf, Reinhard Heller, Klaus-Peter Weiss
-
Publication number: 20180226730Abstract: The disclosed connector can be used to connect superconductive conductors. The connector, which is suitable for electrically connecting at least one first superconductive conductor to at least one second superconductive conductor, includes an electrically conductive base element having a first end portion and a second end portion, and at least one superconductive additional element arranged in the base element extending from the first end portion to the second end portion of the base element.Type: ApplicationFiled: August 10, 2016Publication date: August 9, 2018Applicant: Karlsruher Institut für TechnologieInventors: Walter Fietz, Michael J. Wolf, Reinhard Heller, Klaus-Peter Weiss