Abstract: An antiphlogistic analgesic adhesive which comprisesa flexible substrate andan indomethacin containing pressure-sensitive adhesive layer closely contacting said flexible substrate, wherein said pressure-sensitive adhesive layer comprises a mixture of(a) indomethacin,(b) a copolymer of (i) an alkyl acrylate having 4 to 11 carbon atoms in the alkyl moiety and (ii) a functional monomer having a functional group in the molecule thereof and/or a vinyl monomer, which has pressure-sensitive adhesive properties at room temperature, and(c) an absorption accelerating assistant which maintains said indomethacin in a solubilized state in said copolymer and has skin diffusibility.