Abstract: Provided are degasification devices and methods of degasifying a liquid. Methods of degasifying a liquid can include filling a liquid chamber with a liquid; increasing an internal volume of the liquid chamber to generate a vacuum within the liquid chamber; applying one or more pressure waves to the liquid in the liquid chamber to accelerate the formation of a plurality of gas bubbles which rise to the surface of the liquid and release gas within the plurality of gas bubbles into a space above the liquid in the liquid chamber; and decreasing the internal volume of the liquid chamber to force the gas through a vapor outlet of the liquid chamber, wherein a degassed liquid remains in the liquid chamber.