Patents Assigned to Kazusa DNA Research Institute Foundation
  • Partial homologous recombination of DNA chain
    Publication number: 20040180374
    Abstract: The present invention provides a method of constructing a circular DNA library having an increased content of a desired nucleic acid by removing a specific DNA from the circular DNA library by using a RecA protein. More specifically, the present invention provides a method of constructing a DNA library having an increased content of the first dsDNA by removing a second dsDNA different from the first dsDNA from a DNA library containing the first dsDNA to be increased in content and the second dsDNA.
    Type: Application
    Filed: March 10, 2004
    Publication date: September 16, 2004
    Applicants: Aisin Cosmos R&D Co., Ltd., Kazusa DNA Research Institute Foundation
    Inventors: Kazuhiro Kondo, Michio Oishi, Osamu Ohara
  • DNA encoding IGA nephropathy indicating protein
    Patent number: 6790944
    Abstract: The present invention relates to a novel protein isolated from the leukocyte of IgA nephropathy patients, and DNA encoding the protein. It also relates to an oligonucleotide based on the nucleotide sequence complementary with the DNA, an antibody which specifically reacts with the protein and, furthermore, diagnostic and therapeutic drugs of IgA nephropathy comprising it.
    Type: Grant
    Filed: August 5, 1998
    Date of Patent: September 14, 2004
    Assignees: Kyowa Hakko Kogyo Co., Ltd., Kazusa DNA Research Institute Foundation
    Inventors: Tetsuyoshi Ishiwata, Mikiko Sakurada, Ayako Kawabata, Satoshi Nakagawa, Tetsuro Kuga, Tatsunari Nishi, Nobuo Nomura, Takahiro Nagase, Shigemasa Sawada, Masami Takei
  • Novel gene and protein encoded by the gene
    Publication number: 20040106127
    Abstract: Novel DNAs containing the regions which encodes proteins have been directly cloned from cDNA libraries derived from the human adult whole brain and the human embryonic whole brain, the nucleotide sequences thereof have been determined, and their functions have been identified.
    Type: Application
    Filed: June 24, 2003
    Publication date: June 3, 2004
    Applicants: KAZUSA DNA RESEARCH INSTITUTE FOUNDATION, ProteinExpress Co. Ltd.
    Inventors: Takahiro Nagase, Daisuke Nakajima, Osamu Ohara, Reiko Kikuno
  • Method of reconstituting a DNA library using RecA protein
    Patent number: 6613522
    Abstract: The present invention provides a method of constructing a DNA library having increased proportion of a desired nucleic acid(s) therein by removing a nucleic acid(s) other than the desired nucleic acid(s) from a parent library.
    Type: Grant
    Filed: June 1, 2001
    Date of Patent: September 2, 2003
    Assignees: Aisin Cosmos R&D Co., Ltd., Kazusa DNA Research Institute Foundation
    Inventors: Kazuhiro Kondo, Osamu Ohara, Michio Oishi