Abstract: The present invention relates to a recombinant vector for transcription of the Newcastle disease virus (NDV) genome, a strain of attenuated recombinant NDV with a surface antigen of pathogenic NDV prepared by the vector, a method of preparing a recombinant NDV having low pathogenicity and high protectivity efficiency against Newcastle disease (ND) using the vector, and a vaccine against ND containing the recombinant NDV.
Type:
Grant
Filed:
September 27, 2006
Date of Patent:
May 8, 2012
Assignees:
KBNP, Inc., Biopoa, Inc.
Inventors:
Sun-Hee Cho, Hyuk-Joon Kwon, Sun-Joong Kim, Tae-Eun Kim, Young-Jin An, Mi-Joung Ko, Il-Hwan Kim, Young-Ho Park, Chae-Hyun Kim, Jang-Hyuck Han, Tae-Hwan Kim
Abstract: The present invention relates to an epitope of HN protein in Newcastle disease virus which can be recognized by an avian immune system and an antibody against the epitope, a method for detecting a Newcastle disease virus by using the antibody, and an antigenic variant of Newcastle disease virus carrying changes in the epitope. The epitope of HN protein and the antigenic variant of Newcastle disease virus can be used for developing efficient vaccines, and further, in diagnosing the Newcastle disease virus rapidly and exactly.
Type:
Grant
Filed:
March 23, 2006
Date of Patent:
October 4, 2011
Assignees:
KBNP, Inc., Biopoa, Inc.
Inventors:
Sun-Hee Cho, Hyuk-Joon Kwon, Young-Jin Ahn, Sun-Joong Kim, Young-Ho Park, Chae-Hyun Kim, Tae-Hwan Kim, Tae-Eun Kim
Abstract: The present invention relates to a recombinant vector for transcription of the Newcastle disease virus (NDV) genome, a strain of attenuated recombinant NDV with a surface antigen of pathogenic NDV prepared by the vector, a method of preparing a recombinant NDV having low pathogenicity and high protectivity efficiency against Newcastle disease (ND) using the vector, and a vaccine against ND containing the recombinant NDV.
Type:
Application
Filed:
September 27, 2006
Publication date:
July 22, 2010
Applicant:
KBNP, Inc.
Inventors:
Sun-Hee Cho, Hyuk-Joon Kwon, Sun-Joong Kim, Tae-Eun Kim, Young-Jin An, Mi-Joung Ko, Il-Hwan Kim, Young-Ho Park, Chae-Hyun Kim, Jang-Hyuck Han, Tae-Hwan Kim