Patents Assigned to Keele University
  • Patent number: 9005607
    Abstract: Methods for culturing pluripotent stem cells on fiber scaffolds are provided which result in the expansion of the number of stem cells without loss of pluripotency. Cells obtained by such methods, implants containing such cells and medical methods using such cells are also disclosed.
    Type: Grant
    Filed: March 13, 2013
    Date of Patent: April 14, 2015
    Assignee: Keele University
    Inventors: Deepak Kumar, Ying Yang, Nicholas Forsyth
  • Patent number: 8772248
    Abstract: A compound comprises a thiopeptide, or derivative or analogue thereof, the thiopeptide comprising a C-terminal carboxylic acid group, and a functional group for attachment to a drug, characterized in that the compound is adapted to carry or transport a drug.
    Type: Grant
    Filed: January 17, 2005
    Date of Patent: July 8, 2014
    Assignee: Keele University
    Inventor: Patrick Dawson Bailey
  • Publication number: 20140050704
    Abstract: Methods for culturing pluripotent stem cells on fiber scaffolds are provided which result in the expansion of the number of stem cells without loss of pluripotency. Cells obtained by such methods, implants containing such cells and medical methods using such cells are also disclosed.
    Type: Application
    Filed: March 13, 2013
    Publication date: February 20, 2014
    Applicant: KEELE UNIVERSITY
    Inventors: Deepak Kumar, Ying Yang, Nicholas Forsyth
  • Patent number: 8586068
    Abstract: The present invention utilizes a fatty acid as an attractant in a method of attracting whiteflies. By using a fatty acid as a whitefly attractant, it is possible to attract whiteflies to a desired location. The fatty acid can be used in a lure or other propagator to provide a dispersion of fatty acid in the air, the variation in the concentration of the fatty acid in the air being such that a whitefly is attracted to the lure as the source of the fatty acid. The use of a fatty acid as an attractant results in significantly higher levels of attraction, as measured by the number of whiteflies attracted to a sticky trap, as compared to the use of color alone.
    Type: Grant
    Filed: June 21, 2012
    Date of Patent: November 19, 2013
    Assignee: Keele University
    Inventor: James Gordon Campbell Hamilton
  • Publication number: 20120263773
    Abstract: The present invention utilizes a fatty acid as an attractant in a method of attracting whiteflies. By using a fatty acid as a whitefly attractant, it is possible to attract whiteflies to a desired location. The fatty acid can be used in a lure or other propagator to provide a dispersion of fatty acid in the air, the variation in the concentration of the fatty acid in the air being such that a whitefly is attracted to the lure as the source of the fatty acid. The use of a fatty acid as an attractant results in significantly higher levels of attraction, as measured by the number of whiteflies attracted to a sticky trap, as compared to the use of colour alone.
    Type: Application
    Filed: June 21, 2012
    Publication date: October 18, 2012
    Applicant: KEELE UNIVERSITY
    Inventor: James Gordon Campbell Hamilton
  • Patent number: 8277825
    Abstract: The present invention utilizes a fatty acid as an attractant in a method of attracting whiteflies. By using a fatty acid as a whitefly attractant, it is possible to attract whiteflies to a desired location. The fatty acid can be used in a lure or other propagator to provide a dispersion of fatty acid in the air, the variation in the concentration of the fatty acid in the air being such that a whitefly is attracted to the lure as the source of the fatty acid. The use of a fatty acid as an attractant results in significantly higher levels of attraction, as measured by the number of whiteflies attracted to a sticky trap, as compared to the use of color alone.
    Type: Grant
    Filed: August 19, 2010
    Date of Patent: October 2, 2012
    Assignee: Keele University
    Inventor: James Gordon Campbell Hamilton
  • Publication number: 20120162002
    Abstract: A tomography apparatus for producing image data representative of a dielectric and/or conductivity property distribution within an object using electromagnetic radiation having a frequency in the range 0.05 GHz to 10 GHz, the apparatus having: a processing means for producing image data representative of a dielectric and/or conductivity property distribution within an object located in the imaging domain based on measurement data from the measuring means, wherein the tomography apparatus is configured so that electromagnetic radiation incident on the receivers during a second time period t2 is disregarded for the production of said image data when the apparatus is in use, the second time period t2 being subsequent to a first time period t1 during which electromagnetic radiation is emitted by a selected one of the emitters. The tomography apparatus may include waveguide antennae, the real component ?r? of the complex relative permeability ?r of each waveguide antenna being substantially more than 1.
    Type: Application
    Filed: September 3, 2010
    Publication date: June 28, 2012
    Applicant: KEELE UNIVERSITY
    Inventor: Serguei Semenov
  • Patent number: 7985412
    Abstract: A method of monitoring/controlling Thysanoptera (hereafter thrips) by the use of a behavior modifying compound of Formula (1), wherein Formula (1) is:— where R1 is a monoterpenyl group and R2 is a C3-C5 group.
    Type: Grant
    Filed: August 17, 2005
    Date of Patent: July 26, 2011
    Assignee: Keele University
    Inventors: James Gordon Campbell Hamilton, William Daniel John Kirk
  • Publication number: 20100298816
    Abstract: A method of delivering a reagent into a cell comprising positioning at least one cell, and at least one magnetically susceptible particle attached to the reagent, in the magnetic field of a Halbach array such that the magnetically susceptible particle is attracted to and contacts the cell is described together with an apparatus for delivery of the reagent.
    Type: Application
    Filed: September 10, 2008
    Publication date: November 25, 2010
    Applicant: KEELE UNIVERSITY
    Inventor: Jon Dobson
  • Publication number: 20100184219
    Abstract: A method of preparing cell culture media for use in culturing cells and an apparatus for carrying out the method. The method includes providing a vessel containing cell culture media and exposing the cell culture media to a first controlled atmosphere having a predetermined O2 concentration that is less than an external atmospheric O2 concentration, to reduce the O2 concentration in the cell culture media before culturing cells in the cell culture media. The cell culture media may be agitated during exposure to the first controlled atmosphere. The temperature and/or pressure of the first controlled atmosphere may be controlled.
    Type: Application
    Filed: July 7, 2008
    Publication date: July 22, 2010
    Applicant: KEELE UNIVERSITY
    Inventor: Nicholas Robert Forsyth
  • Patent number: 7625562
    Abstract: There is described a method of magnetically manipulating a cell in vivo which comprises the association of a magnetizable particle with a cell. More particularly, there is described a method of magnetically manipulating a cell which comprises the association of a magnetizable particle with a cell characterized in that the method comprises agonizing or antagonizing ion channels within a cell by the association of a magnetizable particle with a cell. There is also described the use of a magnetizable particle in a method of magnetically manipulating a cell in vivo and/or activating ion channels in vivo.
    Type: Grant
    Filed: June 19, 2003
    Date of Patent: December 1, 2009
    Assignee: Keele University
    Inventors: Alicia Jennifer Hafeeza El Haj, Jon Paul Dobson
  • Patent number: 7553662
    Abstract: A method of culturing tissue comprises growing tissue forming cells whilst subjecting the tissue forming cells to mechanical stresses which are generated magnetically.
    Type: Grant
    Filed: December 19, 2001
    Date of Patent: June 30, 2009
    Assignee: Keele University
    Inventors: Alicia Jennifer Hafeeza El Haj, Jon Paul Dobson
  • Publication number: 20090123366
    Abstract: In order to target a diseased material in a subject, a monocyte, or monocyte-derived cell, such as a macrophage, which incorporates a magnetic material, such as a magnetic particle or a ferrofluid, preferably having a biocompatible coating, is proposed to be administered. A magnetic energy source may then be applied to the subject to destroy, rupture or inactivate the diseased material. Alternatively, the monocyte or monocyte derived cell may additionally include a therapeutic agent, which is thereby targeted at the diseased material.
    Type: Application
    Filed: April 3, 2007
    Publication date: May 14, 2009
    Applicant: Keele University
    Inventors: Jon Dobson, Claire Lewis, Helen Byrne
  • Publication number: 20080286361
    Abstract: The present invention relates to a method of delivery of a therapeutic agent to a target cell the method comprising targeting particles comprising the therapeutic agent to the cell using magnetic means to apply a magnetic force to said particles so as to tend to move said particles towards said magnetic means and at the same time moving said magnetic means.
    Type: Application
    Filed: April 21, 2006
    Publication date: November 20, 2008
    Applicants: KEELE UNIVERSITY, UNIVERSITY OF FLORIDA RESEARCH FOUNDATION
    Inventors: Jon Dobson, Christopher D. Batich
  • Publication number: 20080220267
    Abstract: A glyceride compound comprising a first aliphatic group and a first substituent group bonded to said first aliphatic group. The first substituent group has the formula —O(CH2CH2O)nP where n is 1 to 14 and P is a polymerisable group. An aqueous emulsion of the glyceride can be used in an emulsion polymerisation reaction to yield a polymer resin, which can then be mixed with a suitable base material, such as wood strands, to produce a composite material, such as Oriented Strand Board.
    Type: Application
    Filed: July 20, 2006
    Publication date: September 11, 2008
    Applicants: KEELE UNIVERSITY, ADVANCE ENTERPRISES LTD
    Inventors: James Alan Stephen Howell, Con Robert McElroy, Robert Heathcote, Derek Peter Taylor
  • Patent number: 7034550
    Abstract: A method of measuring ferromagnetic resonance properties of a structure including a non-ferrous material reinforced with steel members, the method includes applying a magnetic field to the structure using a magnet located adjacent the structure, directing microwave radiation towards the structure, and detecting the propagation of microwave radiation that is transmitted or reflected by the steel members, the measuring being made with structure in situ.
    Type: Grant
    Filed: October 1, 2001
    Date of Patent: April 25, 2006
    Assignee: Keele University
    Inventor: Peter William Haycock
  • Patent number: 5864144
    Abstract: An infrared (IR) radiation emitting device comprises a sinuous foil resistive element (1) which emits IR radiation when heated by an electric current. The device is configured so that the resistive element (1) emits radiation with a spatial intensity which substantially possesses a single axis. The resistive element (1) may, for example, be configured as a substantially planar spiral (3).
    Type: Grant
    Filed: June 9, 1997
    Date of Patent: January 26, 1999
    Assignee: Keele University
    Inventor: Derek Charles Laine
  • Patent number: 5827620
    Abstract: Solid oxide fuel cell structures which are capable of relatively rapid temperature changes without cracking and which are simple to seal. In one arrangement, a tubular SOFC structure comprises a self-supporting extruded tube of zirconium oxide with inner and outer electrodes. The tube may have an outside diameter of from, for example, 1 to 5 mm and a wall thickness of from, for example, 50 to 200 microns. In an alternative arrangement, a simple gas type planar interconnect for a planar SOFC is provided in the form of a sheet of ceramic material having electrically conducting bodies of ceramic material embedded in it so as to provide an electrical path through the sheet. To avoid edge sealing problems, fuel gas and air may be delivered to a stacked SOFC structure through tubes extending between adjacent cell sub-assemblies such that the gas is delivered to a central portion of each anode of the cell stack and flows outwards towards the edges of the stack.
    Type: Grant
    Filed: November 24, 1995
    Date of Patent: October 27, 1998
    Assignee: Keele University
    Inventor: Kevin Kendall
  • Patent number: 5814347
    Abstract: A therapeutic composition for the treatment of virus-induced cutaneous infections comprises a first material for blocking viral DNA replication and a second finely divided material which absorbs exudated fluid from vesicles. Preferred compositions comprise a lithium compound (as the material for blocking viral DNA replication) and silica (as the material for absorbing exudated fluid from vesicles). An example of composition in accordance with the invention comprises a lithium compound dissolved or suspended in an aqueous silica salt.
    Type: Grant
    Filed: November 6, 1995
    Date of Patent: September 29, 1998
    Assignee: Keele University
    Inventor: James Derek Birchall
  • Patent number: 5738684
    Abstract: There is described an external fixator for use in the treatment of a fractured bone having a first bone fragment and a second bone fragment which external fixator comprises:a first movable element and;a second movable element,wherein the first movable element is movably mounted in the fixator so as to be capable of angular motion in one plane, and the second movable element is movably mounted in the fixator so as to be capable of angular motion in another plane, with the plane in which the second element moves being substantially orthogonal to the plane in which the first element moves, and the first and second movable elements are coupled together in such a way as to allow simultaneous angular movement of the external fixator in the two substantially orthogonal planes.
    Type: Grant
    Filed: April 30, 1996
    Date of Patent: April 14, 1998
    Assignees: Keele University, Staffordshire University Enterprises Limited
    Inventors: Peter Brian Macfarlane Thomas, Peter Jan Ogrodnik, Christopher Ian Moorcroft