Patents Assigned to KELLBENX INC.
  • Monoclonal antibodies with specificity for fetal erythroid cells
    Patent number: 9453841
    Abstract: The present invention concerns a monoclonal antibody and corresponding hybridoma cells and antigens suitable for isolating fetal cells from maternal blood. The inventive monoclonal antibody reacts with a surface antigen present on fetal red blood cells including their nucleated precursor cells, but not with surface antigens on adult erythroid cell.
    Type: Grant
    Filed: October 14, 2015
    Date of Patent: September 27, 2016
    Assignee: KellBenx Inc.
    Inventors: Christiane Hollmann, Silke Zimmermann, Stefan Stachelhaus, Winfried Albert
  • MONOCLONAL ANTIBODIES WITH SPECIFICITY FOR FETAL ERYTHROID CELLS
    Publication number: 20160084837
    Abstract: The present invention concerns a monoclonal antibody and corresponding hybridoma cells and antigens suitable for isolating fetal cells from maternal blood. The inventive monoclonal antibody reacts with a surface antigen present on fetal red blood cells including their nucleated precursor cells, but not with surface antigens on adult erythroid cell.
    Type: Application
    Filed: October 14, 2015
    Publication date: March 24, 2016
    Applicant: KELLBENX INC.
    Inventors: Christiane HOLLMANN, Silke ZIMMERMANN, Stefan STACHELHAUS, Winfried ALBERT
  • MONOCLONAL ANTIBODIES WITH SPECIFICITY FOR FETAL ERYTHROID CELLS
    Publication number: 20160039932
    Abstract: The present invention concerns a monoclonal antibody and corresponding hybridoma cells and antigens suitable for isolating fetal cells from maternal blood. The inventive monoclonal antibody reacts with a surface antigen present on fetal red blood cells including their nucleated precursor cells, but not with surface antigens on adult erythroid cell.
    Type: Application
    Filed: August 13, 2015
    Publication date: February 11, 2016
    Applicant: KELLBENX INC.
    Inventors: Christiane HOLLMANN, Silke ZIMMERMANN, Stefan STACHELHAUS, Winfried ALBERT
  • Monoclonal antibodies with specificity for fetal erythroid cells
    Patent number: 9194871
    Abstract: The present invention concerns a monoclonal antibody and corresponding hybridoma cells and antigens suitable for isolating fetal cells from maternal blood. The inventive monoclonal antibody reacts with a surface antigen present on fetal red blood cells including their nucleated precursor cells, but not with surface antigens on adult erythroid cell.
    Type: Grant
    Filed: September 16, 2013
    Date of Patent: November 24, 2015
    Assignee: KellBenx Inc.
    Inventors: Christiane Hollmann, Silke Zimmermann, Stefan Stachelhaus, Winfried Albert
  • DETECTION, ISOLATION AND ANALYSIS OF RARE CELLS IN BIOLOGICAL FLUIDS
    Publication number: 20150133332
    Abstract: The invention provides a method for isolating or enriching a rare cell from a biological fluid of a mammal employing an antibody that binds a cell-surface antigen of the rare cell. The immobilized antibody is incubated with a sample of biological fluid that includes the rare cells and a plurality of other cells so as to form an antibody-rare cell complex. The complex can be detected or isolated and subsequently analyzed by any of a variety of physical, chemical and genetic techniques.
    Type: Application
    Filed: August 21, 2014
    Publication date: May 14, 2015
    Applicant: KELLBENX INC.
    Inventors: Javad Khosravi, Leonard H. Kellner, Hassan Bennani
  • DETECTION, ISOLATION AND ANALYSIS OF RARE CELLS IN BIOLOGICAL FLUIDS
    Publication number: 20130122492
    Abstract: The invention provides a method for isolating or enriching a rare cell from a biological fluid of a mammal employing an antibody that binds a cell-surface antigen of the rare cell. The immobilized antibody is incubated with a sample of biological fluid that includes the rare cells and a plurality of other cells so as to form an antibody-rare cell complex. The complex can be detected or isolated and subsequently analyzed by any of a variety of physical, chemical and genetic techniques.
    Type: Application
    Filed: November 14, 2011
    Publication date: May 16, 2013
    Applicant: KELLBENX INC.
    Inventors: Javad Khosravi, Leonard H. Kellner, Hassan Benanni