Abstract: A medicament to be applied as an external preparation for therapeutic treatment of a local symptom of a neuropathic disease, which contains gabapentin or pregabalin in the form of an aqueous solution.

Abstract: A medicament to be applied as an external preparation for therapeutic treatment of a local symptom of a neuropathic disease, which contains gabapentin or pregabalin in the form of an aqueous solution.

Abstract: A medicament to be applied as an external preparation for therapeutic treatment of a local symptom of a neuropathic disease, which contains gabapentin or pregabalin in the form of an aqueous solution.

Abstract: A medicament for therapeutic and/or preventive treatment of Alzheimer's disease, which comprises a combination of a retinoic acid receptor (RAR) agonist such as Am80 and a retinoid X receptor (RXR) agonist such as HX630.

Abstract: A medicament to be applied as an external preparation for therapeutic treatment of a local symptom of a neuropathic disease, which contains gabapentin or pregabalin in the form of an aqueous solution.

Abstract: A medicament for therapeutic and/or preventive treatment of Alzheimer's disease, which comprises a combination of a retinoic acid receptor (RAR) agonist such as Am80 and a retinoid X receptor (RXR) agonist such as HX630.

Abstract: A compound represented by the formula (I) [at least one of R1, R2, and R3 represents a cyclic alkyl group, the remaining represents a linear or branched alkyl group; n represents 0 or 1; R4 represents an amino group or —(CX2)m—COOH (m represents 0 to 3, and X represents hydrogen atom); and R5 represents —(CY2)p—COOR6 (p represents 0 to 3, Y represents hydrogen atom, and R6 represents hydrogen atom or an alkyl group)], or a salt thereof.

Abstract: A compound represented by the formula (I) [at least one of R1, R2, and R3 represents a cyclic alkyl group, the remaining represents a linear or branched alkyl group; n represents 0 or 1; R4 represents an amino group or —(CX2)m—COOH (m represents 0 to 3, and X represents hydrogen atom); and R5 represents —(CY2)p—COOR6 (p represents 0 to 3, Y represents hydrogen atom, and R6 represents hydrogen atom or an alkyl group)], or a salt thereof.

Abstract: A compound represented by the formula (I) [R1 to R3 represent an alkyl group, an alkenyl group, and the like; n represents 0 or 1; R4 represents an amino group or —(CX2)m—COOH (m represents 0 to 3, and X represents hydrogen atom); R5 represents —(CY2)p—COOR6 (p represents an 0 to 3, Y represents hydrogen atom, and R6 represents hydrogen atom or an alkyl group)], or a salt thereof.

Abstract: A compound represented by the formula (I) [R1 to R8 represent an alkyl group, an alkenyl group, and the like; n represents 0 or 1; R4 represents an amino group or —(CX2)m—COOH (m represents 0 to 3, and X represents hydrogen atom); R5 represents —(CY2)p—COOR6 (p represents an 0 to 3, Y represents hydrogen atom, and R6 represents hydrogen atom or an alkyl group)], or a salt thereof.

Abstract: A medicament for promoting memory consolidation, which comprises, as an active ingredient, a non-natural retinoid, preferably a retinoid having a basic skeleton comprising an aromatic ring bound with an aromatic carboxylic acid or tropolone by means of a bridging group, more preferably 4-[(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)carbamoyl]benzoic acid or 4-[(3,5-bis-trimethylsilylphenyl)-carboxamido]benzoic acid.

Abstract: A medicament for promoting memory consolidation, which comprises, as an active ingredient, a non-natural retinoid, preferably a retinoid having a basic skeleton comprising an aromatic ring bound with an aromatic carboxylic acid or tropolone by means of a bridging group, more preferably 4-[(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)carbamoyl]benzoic acid or 4-[(3,5-bis-trimethylsilylphenyl)-carboxamido]benzoic acid.

Abstract: Method for therapeutic treatment of inflammatory bowel disease, including Crohn's disease, comprising administering to a patient in need thereof a therapeutically effective amount of a composition comprising a retinoid as an active ingredient to treat the inflammatory bowel disease, the retinoid being selected from the group consisting of 4-[(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl) carbamoyl]benzoic acid, 4-[(3,5-bis-trimethylsilylphenyl)carboxamido]benzoic acid, 4-[2,3-(2,5-dimethyl-2,5-hexano)dibenzo[b,f][1,4]thiazepin-11-yl]benzoic acid, and 4-(5H-7,8,9,10-tetrahydro-5,7,7,10,10-pentamethylbenzo[e]naphtho[2,3-b][1,4]diazepin-13-yl)benzoic acid.

Abstract: A medicament having an anti-wrinkle action, which comprises as an active ingredient a retinoid having a fundamental structure of a phenyl substituted carbamoyl benzoic acid or a phenyl substituted carboxamide benzoic acid (for example, 4-(3,5-bis(trimethylsilyl)phenylcarboxamide) benzoic acid, 4-[(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)carbamoyl]benzoic acid, or the like).

Abstract: A medicament for preventive and/or therapeutic treatment of a physical dysfunction such as motor dysfunction caused by nerve damage resulting from an accident, cerebral crisis and the like, which comprises as an active ingredient a compound or a salt thereof represented by the following general formula (I): wherein R1 to R5 represents hydrogen atom, an alkyl group, or an alkyl-substituted silyl group, X represents —CONH— or —NHCO—, and A represents a carboxylic acid-substituted aromatic group which may be substituted or a tropolonyl group which may be substituted.

Abstract: A medicament for preventive and/or therapeutic treatment of a lower urinary tract symptom caused by a lower urinary tract disorder, which comprises as an active ingredient a retinoid such as, for example, 4-[(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2 -naphthalenyl)carbamoyl]benzoic acid.

Abstract: A medicament for preventive and/or therapeutic treatment of a bowel diseases such as inflammatory bowel diseases including Crohn's disease, which comprises as an active ingredient a retinoid such as, for example, 4-[(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)carbamoyl]benzoic acid.

Abstract: A medicament for preventive and/or therapeutic treatment of a bowel diseases such as inflammatory bowel diseases including Crohn's disease, which comprises as an active ingredient a retinoid such as, for example, 4-[(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)carbamoyl]benzoic acid.