Abstract: A hand-held aerosol dispenser for a therapeutic liquid for inhalation therapy with an atomizer nozzle disposed in a housing for the delivery of compressed air is provided with a detachable reservoir for the liquid. The liquid is aspirated by the Venturi principle through a duct discharging in the region of the atomizer nozzle and atomized into very fine particles using a baffle element opposite the atomizing nozzle. The reservoir, which corresponds in its dimensions to the dimensions of the housing, is detachably accommodated in the lower part of the housing. The duct, discharging in the region of the atomizing nozzle, is elongated downward by a suction nozzle, which passes through an upper opening of the reservoir into the vicinity of the bottom of the reservoir. The reservoir contains sterile water or a mixture of sterile water and drug.