Patents Assigned to Kereos, Inc.
  • Linkers for anchoring targeting ligands
    Patent number: 7998462
    Abstract: An improved linker which lacks chiral centers between a hydrophobic anchor for coupling to lipid-based particles and a targeting agent has suitable hydrophobic/hydrophilic properties for use in vivo.
    Type: Grant
    Filed: October 16, 2007
    Date of Patent: August 16, 2011
    Assignee: Kereos, Inc.
    Inventor: William D. McGhee
  • BIOCONJUGATES OF METAL COMPLEXES OF NITROGEN-CONTAINING MACROCYCLIC LIGANDS
    Publication number: 20090098047
    Abstract: The present invention is directed to bioconjugates of complexes represented by the formula: wherein R, R?, R1, R?1, R2, R?2, R3, R?3, R4, R?4, R5, R?5, R6, R?6, R7, R?7, R8, R?8, R9, R?9, M, X, Y, Z and n are defined herein for use as contrast agents in diagnostic imaging.
    Type: Application
    Filed: August 4, 2008
    Publication date: April 16, 2009
    Applicants: Inotek Pharmaceuticals, Kereos, Inc.
    Inventors: William L. Neumann, Dennis P. Riley, Randy H. Weiss, Susan L. Henke, Patrick J. Lennon, Karl W. Aston
  • Lipophilic derivatives of chelate monoamides
    Patent number: 7504088
    Abstract: Compounds useful for associating with nanoparticle or microparticle emulsions to obtain magnetic resonance images permit control of the relaxivity of the signal and readily associate with the particulate components. The compounds are conveniently prepared from achiral derivatives of chelating moieties.
    Type: Grant
    Filed: June 7, 2005
    Date of Patent: March 17, 2009
    Assignee: Kereos, Inc.
    Inventors: Dennis Patrick Riley, William D. McGhee