Patents Assigned to Kernforschungsanlage Juelich GmbH
  • Patent number: 5264347
    Abstract: The selective determination of .alpha.-ketoisocaproate in samples of body fluids, especially in serum, is achieved, without previous separation, directly in the fluid and in the presence of NADH, by means of a KIC-specific D-.alpha.-hydroxy-isocaproic dehydrogenase that originates specifically from strains of Lactobacillus casei producing this enzyme, in particular strains of Lactobacillus casei subspecies pseudoplantarum or casei. The KIC determination is used, in particular, for diagnosing maple syrup urine disease. Expedient for this purpose are analytical kits which have a divisible stock of D-.alpha.-hydroxyisocaproic dehydrogenase from Lactobacillus casei, in particular from the Lactobacillus casei (DSM 20008).
    Type: Grant
    Filed: August 5, 1992
    Date of Patent: November 23, 1993
    Assignee: Kernforschungsanlage Juelich GmbH
    Inventors: Werner Hummel, Udo Wendel, Peter Schadewaldt
  • Patent number: 5159694
    Abstract: The coalescence and release of bubbles from packing that supports the growth of microorganisms is promoted by mechanical action on the packed bed arrangement, in particular by continuous or intermittent vibrations, rotations, or by rocking motions. With particular advantage, a reactor vessel which is typically tubular is filled with packing upon which microbial growth is sustained, preferably leaving a free space of 10% to 35%, in particular 15% to 20%. The reactor vessel has an axis that is substantially horizontal but preferably inclined by at least about, and is set continuously or intermittently, for example, by an axle drive or by means of friction wheel drive, into rotational or rocking motions about that axis. The gas can be discharged, for example, via valves and a cam mechanism. Alternatively, a vent pipe, taken through the hollow shaft on the discharge side and upwards, can be provided behind a screen plate.
    Type: Grant
    Filed: July 18, 1990
    Date of Patent: October 27, 1992
    Assignee: Kernforschungsanlage Juelich GmbH
    Inventors: Horst Overath, Carl-Johannes Soeder, Nazir Salhani
  • Patent number: 5096814
    Abstract: For the immobilization of micro-organisms and animal cells, in particular for anaerobic processes, such as the purification of waste water or for the biotechnological production of nutrition-essential or pharmacological substances, porous, sintered bodies are employed (inorganic carrier bodies). In particular, sintered glass in the form of Raschig rings with a double-pore structure, are employed. They have porosity-determining through-going macropores that permit a free exchange of fluid and gas from the interior of the carrier to the surroundings, and open micropores within the macropore walls, the diameter of the micropores being of the same order of magnitude as the size of the micro-organisms or cells. These carrier bodies typically have an open pore volume of 35% to 85%, 20% to 80% being accounted for by the macropores having a diameter of 20 to 500 .mu.m, and 5%-50% by micropores having a diameter of 1-10 .mu.m.
    Type: Grant
    Filed: December 29, 1989
    Date of Patent: March 17, 1992
    Assignees: Kernforschungsanlage Juelich GmbH, Schott Glaswerke
    Inventors: Alexander Aivasidis, Christian Wandrey, Werner Kiefer
  • Patent number: 5008192
    Abstract: An enzymatic reaction of aliphatic, aromatic or heteroaromatic aldehydes or ketones with hydrocyanic acid to form the corresponding (R)-cyanohydrins or (S)-cyanohydrins is carried out in an aqueous medium in the presence of (R)-oxynitrilase ( or oxynitrilase ( under acid conditions and at temperatures such that the competing chemical reaction and racemization are negligible compared with the enzymatic synthesis. The process is preferably carried out at a pH of .ltoreq.4.5 and at reaction temperatures between C. and C. The reaction is preferably carried out continuously, advantageously in an enzyme membrane reactor. Of particular interest is the conversion of aromatic aldehydes into the corresponding optically active cyanohydrins.
    Type: Grant
    Filed: January 30, 1989
    Date of Patent: April 16, 1991
    Assignees: Kernforschungsanlage Juelich GmbH, Degussa Aktiengesellschaft
    Inventors: Uwe Neidermeyer, Udo Kragl, Maria R. Kula, Christian Wandrey, Kyriakos Makrylaleas, Karlheinz Drauz
  • Patent number: 4935360
    Abstract: An anaerobic production of acetic acid by fermentation can employ homoacetogenic bacteria in an aqueous solution of fermentable substrates, especially sugar, with the result of increased acetic-acid concentrations (over 3%), when the substrate solution initially used in the fermentation already contains acetic acid, for example, from a previous fermentation. In a fed-batch process, acetic acid is preferably present in a concentration ranging from about 0.5% to about 2%, and especially around 1%. At least two fermenters in compound (interconnected) arrangement are used. A real continuous fermentation is realized in at least two sequentially-operated fermenters by regulating the residence time in the first at about 1 day and in the second fermenter at at least 2 days.
    Type: Grant
    Filed: June 1, 1987
    Date of Patent: June 19, 1990
    Assignees: Kernforschungsanlage Juelich GmbH, Pfeifer Langen
    Inventors: Robert Klemps, Siegfried Schoberth, Hermann Sahm, Werner Swyzen
  • Patent number: 4915039
    Abstract: A process for heat-treating refuse comprising the steps of decomposing in a combustion furnace a quantity of refuse into slag, emitted gas and fly dust. The fly dust is separated into a fine dust fraction and a coarse dust fraction. The coarse dust fraction is fed back to the combustion chamber, and the fine dust fraction is treated for removal of desired constituents.
    Type: Grant
    Filed: July 20, 1988
    Date of Patent: April 10, 1990
    Assignee: Kernforschungsanlage Juelich GmbH
    Inventor: Helmut Ringel
  • Patent number: 4900506
    Abstract: A high-temperature reactor with a reactor core containing fuel elements crossed by a cooling gas circuit comprises a malfunction filter for filtering metal fission products discharged from the fuel elements in the event of core overheating. The filter is mounted in the cooling gas circuit outside the reactor core and consists of a carbon which is incompletely graphitized, or is not graphitized at all.
    Type: Grant
    Filed: December 7, 1987
    Date of Patent: February 13, 1990
    Assignee: Kernforschungsanlage Juelich GmbH
    Inventors: Rainer Moormann, Klaus Hilpert, Karl Verfondern
  • Patent number: 4777013
    Abstract: A high-temperature gas cooled nuclear reactor system comprises a containment building, a concrete reactor pressure vessel inside the containment building, and a safety relief valve connected to the concrete reactor pressure vessel. The spring of the safety valve consists of a material with a spring constant decreasing as temperature rises. A heat exchanger is provided in close proximity to cool the spring of the safety valve which is subject to the heat of the reactor coolant escaping when the safety valve is open. The heat exchanger of the safety valve is connected to a liner cooling system of the concrete reactor pressure vessel.
    Type: Grant
    Filed: July 24, 1986
    Date of Patent: October 11, 1988
    Assignee: Kernforschungsanlage Juelich GmbH
    Inventors: Johannes P. Wolters, Manfred Nickel
  • Patent number: 4771527
    Abstract: A tool, mainly for placing by remote-control a tensioning roller chain or a like tightening element around a flange, in particular in nuclear works, and thereupon to carry out tightening, the ends of the tensioning roller chain being connected by a tensioning system including a tightening bolt, characterized by gripper members to seize the ends of the tensioning roller chain and by gripper arms on which the gripper members are mounted and of which at least one arm is kinematically displaceable by a displacement system in such a manner that the ends of the tensioning roller chain can be guided around the flange and toward each other, and by a coupling at one of the gripper arms for detachably engaging the tightening bolt so that a tensioning motor may drive the coupling and thereby tighten the roller chain about the flange and so that the gripper arms may thereupon disengage from the coupling and the roller chain remain tightened about the flange.
    Type: Grant
    Filed: April 16, 1987
    Date of Patent: September 20, 1988
    Assignee: Kernforschungsanlage Juelich GmbH
    Inventors: Klaus Doring, Herbert Haas
  • Patent number: 4768315
    Abstract: A shading and heating insulating device, especially for greenhouses, has two films of flexible plastic material interconnected to form a type of pouch enclosing a hollow space, which is preferably divided into a plurality of tunnels. A supply pipe is operatively quick-coupled to one end of a distribution conduit, the jacket of which is operatively connected to one edge of the hollow space for feeding a pourable heat insulating material into the hollow space. A return pipe may be operatively quick-coupled to a collection conduit, the jacket of which is operatively connected to an opposite edge of the hollow space for withdrawing the pourable insulating material out of the hollow space and returning it to a storage container. When the hollow space is empty, the pouch may be rolled up, for example by rotating one of the conduits, or the pouch may be folded after release of at least one quick-coupling member.
    Type: Grant
    Filed: July 10, 1987
    Date of Patent: September 6, 1988
    Assignee: Kernforschungsanlage Juelich GmbH
    Inventor: Friedrich W. Grimme
  • Patent number: 4298059
    Abstract: Disclosed is a recuperative heat exchanger, comprising a body of ceramic material having a plurality of generally parallel flow channels arranged adjacently to one another generally axially with respect to the body, with adjacent flow channels having a common partition wall. The plurality of flow channels include a plurality of first flow channels for carrying a first heat transfer medium and a plurality of second flow channels, alternatingly arranged with respect to the first flow channels, for carrying a second heat exchange medium. Each of the first channels has an inlet positioned on one lateral side of the body near a first longitudinal end of the body and an outlet positioned in the opposite, second longitudinal end of the body, and each of the second flow channels has an inlet positioned on one lateral side of the body near the second longitudinal end of the body and an outlet in the first longitudinal end of the body.
    Type: Grant
    Filed: September 24, 1979
    Date of Patent: November 3, 1981
    Assignees: Rosenthal Technik AG, Kernforschungsanlage Juelich GmbH
    Inventors: Axel Krauth, Horst R. Maier, Hans-Juergen Phlmann, Siegfried Foerster, Manfred Kleeman