Abstract: An apparatus (100) for testing electrical activity from a biological tissue sample comprises a body (1) provided with a well (4), stimulating means (8) for stimulating a sample located in the well (4), and detecting means (9) for detecting electrical activity in the sample. In one embodiment the apparatus has a fluid inlet means (10) and a fluid outlet means (16) in fluid communication with the well (4). The inlet means (10) comprises an electrically conductive conduit (11A) which is in fluid contact with a fluid flowing, in use, though the outlet means (16). In some embodiments the apparatus is provided with an electrically conductive member (19) which is in electrical contact with a fluid contained, in use, in at least one of the well (4), inlet means (10) and outlet means (16). The stimulating means (8) and detecting means (9) are engaged with the body (1) by a gripping means (32) which comprises an electrically conductive gripping member (36). Related methods and apparatus are also disclosed.

Abstract: An apparatus (100) for testing electrical activity from a biological tissue sample comprises a body (1) provided with a well (4), stimulating means (8) for stimulating a sample located in the well (4), and detecting means (9) for detecting electrical activity in the sample. In one embodiment the apparatus has a fluid inlet means (10) and a fluid outlet means (16) in fluid communication with the well (4). The inlet means (10) comprises an electrically conductive conduit (11A) which is in fluid contact with a fluid flowing, in use, though the outlet means (16). In some embodiments the apparatus is provided with an electrically conductive member (19) which is in electrical contact with a fluid contained, in use, in at least one of the well (4), inlet means (10) and outlet means (16). The stimulating means (8) and detecting means (9) are engaged with the body (1) by a gripping means (32) which comprises an electrically conductive gripping member (36). Related methods and apparatus are also disclosed.