Abstract: A diagnostic test paper detects abuse-type drugs in a test specimen of a biological fluid. A particular method of making the diagnostic test paper includes impregnating a bibulous carrier material with the dry residue of a reagent reactive to abuse-type drugs. A particular method is used for screening a biological fluid to determine the presence of abuse-type drugs therein. A test specimen applying area is located on the bibulous carrier material adjacent one side of a concentrated reagent zone having a first color. A particular method of application and a specific syringe device is used to apply a test specimen that has been prepared under very precise conditions. The test specimen moves from the particular applying area into the concentrated reagent zone to produce the specific results of detecting the presence of abuse-type drugs therein. A novel solvent composition is used to prepare the test specimen applied to the bibulous carrier material of the invention.