Patents Assigned to Keystone Heart Ltd.
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Publication number: 20230414336Abstract: In general, the invention features an intra-vascular device for filtering or deflecting emboli or other large objects from entering a protected secondary vessel or vessels. the device of the invention may include a filter to prevent a particle in a blood vessel from passing through the filter, a lateral structure to hold the filter, and two wires attached to lateral structure, on each at its distal and proximal ends. These wires may be used to control the deflection or orientation of the filter upon its installation within a blood vessel. Further, in some embodiments, these wires may be capable of readily detaching from the device, thus making it possible to install a filter without any significant appendages in a blood vessel.Type: ApplicationFiled: August 11, 2023Publication date: December 28, 2023Applicant: Keystone Heart Ltd.Inventors: Yuval SHEZIFI, Iddo SALMAN, Tzeela Mikovski SHEMESH
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Patent number: 11850137Abstract: An intra-aortic device comprising a filter and a frame defining the shape of the filter, wherein the frame is intrinsically curved in a superior direction by a proximal superior bend and/or a distal superior bend, whereupon installation in an aorta, the M frame flattens.Type: GrantFiled: February 25, 2022Date of Patent: December 26, 2023Assignee: Keystone Heart Ltd.Inventor: Amit Ashkenazi
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Publication number: 20220183814Abstract: An intra-aortic device comprising a filter and a frame defining the shape of the filter, wherein the frame is intrinsically curved in a superior direction by a proximal superior bend and/or a distal superior bend, whereupon installation in an aorta, the M frame flattens.Type: ApplicationFiled: February 25, 2022Publication date: June 16, 2022Applicant: Keystone Heart Ltd.Inventor: Amit Ashkenazi
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Publication number: 20210236258Abstract: A method of manufacturing an emboli filter membrane having a three-dimensional (3D) structure from a sheet of fabric made from at least of strand and a device comprising such filter membrane. The filter membrane is manufactured using a mold made from two parts, a first part having a cavity in the shape of the three-dimensional structure surrounded by a first surface, a second part having a protrusion in the shape of the three-dimensional structure surrounded by a second surface. When the mold is closed there is a space between a surface of the cavity and a surface of the protruding portion.Type: ApplicationFiled: April 23, 2021Publication date: August 5, 2021Applicant: Keystone Heart Ltd.Inventors: Amit Ashkenazi, Valentin Ponomarenko
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Publication number: 20210220110Abstract: An embolic protection device for transvascular delivery to an aortic arch of a patient for protection of side branch vessels of said aortic arch from embolic material. The device comprises a support frame, wherein at least a distal or a proximal portion of the support frame is a spring section configured for providing a radial force between the support frame and a wall of the aortic arch when in an expanded state.Type: ApplicationFiled: April 2, 2021Publication date: July 22, 2021Applicant: Keystone Heart Ltd.Inventors: Amit ASHKENAZI, Tzeela MIKOVSKI SHEMESH, Valentin PONOMARENKO
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Patent number: 11000357Abstract: An embolic protection device for transvascular delivery to an aortic arch of a patient for protection of side branch vessels of said aortic arch from embolic material. The device comprises a support frame, wherein at least a distal or a proximal portion of the support frame is a spring section configured for providing a radial force between the support frame and a wall of the aortic arch when in an expanded state.Type: GrantFiled: February 6, 2018Date of Patent: May 11, 2021Assignee: Keystone Heart Ltd.Inventors: Amit Ashkenazi, Tzeela Mikovski Shemesh, Valentin Ponomarenko
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Publication number: 20210085445Abstract: A method of manufacturing an emboli filter membrane having a three-dimensional (3D) structure from a sheet of fabric made from at least of strand and a device comprising such filter membrane. The filter membrane is manufactured using a mold made from two parts, a first part having a cavity in the shape of the three-dimensional structure surrounded by a first surface, a second part having a protrusion in the shape of the three-dimensional structure surrounded by a second surface. When the mold is closed there is a space between a surface of the cavity and a surface of the protruding portion.Type: ApplicationFiled: October 26, 2018Publication date: March 25, 2021Applicant: Keystone Heart Ltd.Inventors: Amit Ashkenazi, Valentin Ponomarenko
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Patent number: 10856961Abstract: In general, the invention features an intravascular device, a delivery system, and methods for filtering or deflecting emboli or other large objects from entering a protected secondary vessel or vessels The intravascular device of the invention may prevent passage of a particle in a blood vessel from passing through a filter supported by a frame, upper and lower stabilizers, and a wire. The wire may be used to stabilize the device upon its deployment and installation within a blood vessel. Further, in some embodiments, the invention features a delivery system and methods for introduction of the device into a blood vessel.Type: GrantFiled: January 20, 2016Date of Patent: December 8, 2020Assignee: Keystone Heart, Ltd.Inventors: Tzeela Mikovsky Shemesh, Moran Gera, Amit Ashkenazi
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Publication number: 20200289251Abstract: In general, the invention features an intravascular device, a delivery system, and methods for filtering or deflecting emboli or other large objects from entering a protected secondary vessel or vessels The intravascular device of the invention may prevent passage of a particle in a blood vessel from passing through a filter supported by a frame, upper and lower stabilizers, and a wire. The wire may be used to stabilize the device upon its deployment and installation within a blood vessel. Further, in some embodiments, the invention features a delivery system and methods for introduction of the device into a blood vessel.Type: ApplicationFiled: June 2, 2020Publication date: September 17, 2020Applicant: Keystone Heart Ltd.Inventors: Tzeela Mikovsky SHEMESH, Moran GERA, Amit ASHKENAZI
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Patent number: 10624732Abstract: A method for filtering particulate matter from a blood vessel in a patient, including inserting a device into the blood vessel, the device including at least an outer structure capable of insertion into the blood vessel; and an inner filter anchored to the outer structure, the inner filter having a one-way valve though which a medical instrument may be passed.Type: GrantFiled: April 27, 2017Date of Patent: April 21, 2020Assignee: Keystone Heart Ltd.Inventor: Dov V. Shimon
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Publication number: 20200054434Abstract: This invention relates to devices that are inserted in a blood vessel or other body lumen, and in particular to filter that may block particles from entering a blood vessel. Devices of this invention position and secure a filter in a vascular system to intercept particulates, including emboli.Type: ApplicationFiled: October 3, 2019Publication date: February 20, 2020Applicant: Keystone Heart Ltd.Inventors: Moran Gera, Yuval Shezifi
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Patent number: 10500033Abstract: In general, the invention features an intra-vascular device for filtering or deflecting emboli or other large objects from entering a protected secondary vessel or vessels. The device of the invention may include a filter, an central member, additional supporting members, and a delivery cable and may serve to filter or deflect emboli or other large objects from entering protected secondary vessels. The device may be capable of collapse along its longitudinal axis for ease of delivery to the treatment site. The device may further be compatible with common delivery methods used in interventional cardiology (e.g., TAVI procedures). The device may be integrated into the delivery systems. In other embodiments the device may be detachable from the delivery system. Upon deployment, the device may be positioned so as to contact the orifice of one or more secondary blood vessels. Upon retrieval the device may be retracted in an orientation substantially similar to the original deployment orientation.Type: GrantFiled: May 28, 2012Date of Patent: December 10, 2019Assignee: Keystone Heart Ltd.Inventors: Gil Naor, Yuval Shezifi
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Patent number: 10485647Abstract: This invention relates to devices that are inserted in a blood vessel or other body lumen, and in particular to filter that may block particles from entering a blood vessel. Devices of this invention position and secure a filter in a vascular system to intercept particulates, including emboli.Type: GrantFiled: June 11, 2014Date of Patent: November 26, 2019Assignee: Keystone Heart Ltd.Inventors: Moran Gera, Yuval Shezifi
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Publication number: 20190076231Abstract: An intra-aortic device comprising a filter and a frame defining the shape of the filter, wherein the frame is intrinsically curved in a superior direction by a proximal superior bend and/or a distal superior bend, whereupon installation in an aorta, the frame flattens.Type: ApplicationFiled: March 10, 2017Publication date: March 14, 2019Applicant: Keystone Heart Ltd.Inventor: Amit Ashkenazi
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Publication number: 20190038392Abstract: An embolic protection device for transvascular delivery to an aortic arch of a patient for protection of side branch vessels of said aortic arch from embolic material. The device comprises a support frame, wherein at least a distal or a proximal portion of the support frame is a spring section configured for providing a radial force between the support frame and a wall of the aortic arch when in an expanded state.Type: ApplicationFiled: February 6, 2018Publication date: February 7, 2019Applicant: Keystone Heart Ltd.Inventors: Amit ASHKENAZI, Tzeela MIKOVSKI SHEMESH, Valentin PONOMARENKO
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Publication number: 20180177580Abstract: In general, the invention features an intravascular device, a delivery system, and methods for filtering or deflecting emboli or other large objects from entering a protected secondary vessel or vessels The intravascular device of the invention may prevent passage of a particle in a blood vessel from passing through a filter supported by a frame, upper and lower stabilizers, and a wire. The wire may be used to stabilize the device upon its deployment and installation within a blood vessel. Further, in some embodiments, the invention features a delivery system and methods for introduction of the device into a blood vessel.Type: ApplicationFiled: January 20, 2016Publication date: June 28, 2018Applicant: Keystone Heart Ltd.Inventors: Tzeela Mikovsky Shemesh, Moran Gera, Amit Ashkenazi
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Publication number: 20180008392Abstract: In general, the invention features an intravascular device, a delivery system, and methods for filtering or deflecting emboli or other large objects from entering a protected secondary vessel or vessels The intravascular device of the invention may prevent passage of a particle in a blood vessel from passing through a filter supported by a frame, upper and lower stabilizers, and a wire. The wire may be used to stabilize the device upon its deployment and installation within a blood vessel. Further, in some embodiments, the invention features a delivery system and methods for introduction of the device into a blood vessel.Type: ApplicationFiled: January 20, 2016Publication date: January 11, 2018Applicant: Keystone Heart Ltd.Inventors: Tzeela Mikovsky Shemesh, Moran Gera, Amit Ashkenazi
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Publication number: 20170224462Abstract: A method for filtering particulate matter from a blood vessel in a patient, including inserting a device into the blood vessel, the device including at least an outer structure capable of insertion into the blood vessel; and an inner filter anchored to the outer structure, the inner filter having a one-way valve though which a medical instrument may be passed.Type: ApplicationFiled: April 27, 2017Publication date: August 10, 2017Applicant: Keystone Heart Ltd.Inventor: Dov V. Shimon
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Patent number: D881391Type: GrantFiled: April 9, 2018Date of Patent: April 14, 2020Assignee: Keystone Heart Ltd.Inventor: Guy Rogel
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Patent number: D908875Type: GrantFiled: April 16, 2018Date of Patent: January 26, 2021Assignee: Keystone Heart Ltd.Inventors: Amit Ashkenazi, Valentin Ponomarenko