Patents Assigned to KINE SCIENCES CO., LTD.
  • Patent number: 11730788
    Abstract: The present invention relates to use of peptides as a therapeutic agent, wherein it has been confirmed that the peptides of the present invention significantly inhibit the activity of T cells and the differentiation of T helper 17 cells (Th17 cells), which are associated with autoimmune disease, reduce the secretion of inflammatory cytokine IL-6, and have remarkable effects of treating and improving arthritis in an animal model of arthritis. Therefore, the peptides may be used as an active ingredient in therapeutic agents for various autoimmune diseases such as bone disease, inflammatory disease or rheumatoid arthritis.
    Type: Grant
    Filed: September 14, 2018
    Date of Patent: August 22, 2023
    Assignee: KINE SCIENCES CO., LTD.
    Inventors: Dae Ho Cho, Kyung Eun Kim, Myun Soo Kim, Sun Young Park, Hee Young Jung
  • Patent number: 11648286
    Abstract: The present invention relates to use of peptides as a therapeutic agent, wherein it has been confirmed that the peptides of the present invention significantly inhibit the activity of T cells and the differentiation of T helper 17 cells (Th17 cells), which are associated with autoimmune disease, reduce the secretion of inflammatory cytokine IL-6, and have remarkable effects of treating and improving arthritis in an animal model of arthritis. Therefore, the peptides may be used as an active ingredient in therapeutic agents for various autoimmune diseases such as bone disease, inflammatory disease or rheumatoid arthritis.
    Type: Grant
    Filed: September 14, 2018
    Date of Patent: May 16, 2023
    Assignee: KINE SCIENCES CO., LTD.
    Inventors: Dae Ho Cho, Kyung Eun Kim, Myun Soo Kim, Sun Young Park, Hee Young Jung
  • Patent number: 11629169
    Abstract: The present invention relates to use of peptides as a therapeutic agent, wherein it has been confirmed that the peptides of the present invention significantly inhibit the activity of T cells and the differentiation of T helper 17 cells (Th17 cells), which are associated with autoimmune disease, and have remarkable effects of treating and improving arthritis in an animal model of arthritis. Therefore, the peptides may be used as an active ingredient in therapeutic agents for various autoimmune diseases such as bone disease, inflammatory disease or rheumatoid arthritis.
    Type: Grant
    Filed: September 14, 2018
    Date of Patent: April 18, 2023
    Assignee: KINE SCIENCES CO., LTD.
    Inventors: Dae Ho Cho, Kyung Eun Kim, Myun Soo Kim, Sun Young Park, Hee Young Jung
  • Patent number: 10995117
    Abstract: Provided is a novel peptide for skin regeneration or wound healing and a use thereof. The novel peptide not only promotes the wound healing by increasing the production amount of collagen in dermal fibroblasts but also has an excellent whitening effect by inhibiting the production amount of melanin and tyrosinase activity of melanoma cells, and consists of peptides having a very small size to minimize side effects according to administration of external substances of very small peptides. As a result, it is expected that the novel peptide can be used as an active substance that can replace existing skin regeneration or would therapeutic agents.
    Type: Grant
    Filed: December 17, 2018
    Date of Patent: May 4, 2021
    Assignee: KINE SCIENCES CO., LTD.
    Inventors: Dae Ho Cho, Min Chan Gil, So Mi Lee, Myun Soo Kim
  • Patent number: 10913772
    Abstract: Provided is a peptide for preventing or treating inflammatory diseases and a use thereof. According to a novel dimeric peptide according to the present invention, it is possible to not only exhibit an excellent therapeutic effect through anti-inflammatory action but also have a very small-sized peptide, thereby minimizing side effects due to the administration of external substances and will be expected to be used as an active substance that can replace existing therapeutic agents for inflammatory diseases.
    Type: Grant
    Filed: January 3, 2019
    Date of Patent: February 9, 2021
    Assignee: KINE SCIENCES CO., LTD.
    Inventors: Dae Ho Cho, Kyung Eun Kim, Sun Young Park, Youn Kyung Houh
  • Patent number: 10913771
    Abstract: Provided is a novel peptide for preventing or treating inflammatory diseases and a use thereof. According to the novel dimeric or trimeric peptide, it is possible to not only exhibit an excellent therapeutic effect through anti-inflammatory action but also have a very small-sized peptide, thereby minimizing side effects due to the administration of external substances. Therefore, it is expected that the peptide can be used as an active substance that can replace existing therapeutic agents for inflammatory diseases.
    Type: Grant
    Filed: December 17, 2018
    Date of Patent: February 9, 2021
    Assignee: KINE SCIENCES CO., LTD.
    Inventors: Dae Ho Cho, Kyung Eun Kim, Sun Young Park, Myung Jin Jung, Joo Hyun Lee