Patents Assigned to KINETA TWO, LLP
  • DETECTION OF MUTATIONS IN A GENE ASSOCIATED WTIH RESISTANCE TO VIRAL INFECTION, OAS1
    Publication number: 20120253027
    Abstract: A method for detecting a mutation related to the gene encoding OAS1. This and other disclosed mutations correlate with resistance of humans to viral infection including hepatitis C. Also provided is a therapeutic agent consisting of a protein or polypeptide encoded by the mutated gene, or a polynucleotide encoding the protein or polypeptide. Inhibitors of human OAS1, including antisense oligonucleotides, methods, and compositions specific for human OAS1, are also provided.
    Type: Application
    Filed: November 22, 2011
    Publication date: October 4, 2012
    Applicant: KINETA TWO, LLP
    Inventors: Shawn P. Iadonato, CHARLES L. MAGNESS, GARY ROSENBERG, CHRISTINA A. SCHERER, THIERRY GUILLAUDEUX