Abstract: Compounds, methods and pharmaceutical compositions for treating viral infections, by administering certain compounds in therapeutically effective amounts are disclosed. Methods for preparing the compounds and methods of using the compounds and pharmaceutical compositions thereof are also disclosed. In particular, the treatment and prophylaxis of viral infections such as caused by the Arenavirus family such as Lassa fever, Argentine hemorrhagic fever, Bolivian hemorrhagic fever, and Venezuelan hemorrhagic fever.
Type:
Grant
Filed:
November 16, 2016
Date of Patent:
June 19, 2018
Assignee:
Kineta Viral Hemorrhagic Fever, LLC
Inventors:
Dongcheng Dai, James R. Burgeson, Sean M. Amberg, Dennis E. Hruby