Patents Assigned to King Abdulaziz University
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Patent number: 11944609Abstract: Provided herein are ionic liquids that can be used as antifungal agents alone or in combination with Amphotericin B. Also disclosed are methods of synthesis of the ionic liquids and inhibiting fungal growth and methods of treating fungal infections using the disclosed compounds. The disclosure provides antifungal agents that potentiate the antifungal activity of Amphotericin B, a commonly used antifungal drug that could be used alone or in combination. This combination will help control and combat the infections caused by drug resistant Candida. auris in immunocompromised patients.Type: GrantFiled: June 16, 2023Date of Patent: April 2, 2024Assignee: KING ABDULAZIZ UNIVERSITYInventors: Sami-ullah Rather, Mohmmad Younus Wani, Hisham S. Bamufleh, Hesham Alhumade, Usman Saeed, Aqeel Ahmad Taimoor, Walid M. Alalayah, Irfan Ahmad Rather
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Patent number: 11912588Abstract: A gas hydrate desalination system that includes a reactor with a detachable water jacket and thermocouples. The reactor has a detachable lid having a liquid inlet, a gas inlet, sapphire glass lenses, and lid cameras. An exit concentrate channel is provided at a bottom of the reactor. A mixing unit of the system includes a liquid storage tank connected to the reactor through the liquid inlet, and a gas feed cylinder connected the reactor through the gas inlet. A resolving unit of the system includes a sieve filter column for filtering brine from gas hydrate. The sieve filter column is connected to the exit concentrate channel and a first fraction column, which is connected to a brine column. The channel is further connected to a second fraction column, which is connected to the brine column for separating freshwater from the gas hydrate.Type: GrantFiled: May 19, 2023Date of Patent: February 27, 2024Assignee: King Abdulaziz UniversityInventors: Hani Abulkhair, Iqbal Rajput, Omar Ahmed Bamaga, Eydhah Almatrafi, Abdulmohsen Omar Alsaiari, Muhammad Albeirutty, Muhammad Khan, Bhajan Lal, Hussam Organgi, Amer Shaiban, Azmi Sharif, Sirisha Nallakukkala
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Patent number: 11906364Abstract: A flexible infrared irradiation and temperature sensor is provided. The sensor includes a substantially cubic deformable rubber substrate and a conductive layer embedded in the rubber substrate, wherein the conductive layer comprises a middle portion comprising a composite film of carbon nanotubes (CNTs) and nickel phthalocyanine (NiPc); and one or more exterior portions comprising carbon nanotubes, wherein the one or more exterior portions do not include NiPc.Type: GrantFiled: July 6, 2021Date of Patent: February 20, 2024Assignee: KING ABDULAZIZ UNIVERSITYInventors: Muhammad Tariq Saeed Chani, Khasan S. Karimov, Abdullah M. Asiri, Tahseen Kamal
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Patent number: 11890380Abstract: A buccal tablet formulation has a polyvinylpyrrolidone K-90 as a solid dispersion polymer, a hydroxypropyl methylcellulose as a mucoadhesive polymer, a sodium deoxycholate as mucopenetration enhancer, a porous silicon dioxide (e.g., FujiSil), mannitol, and avanafil. The ratio of PVP K-90 to AVA is approximately 2:1 (e.g., 2.3:1 to 1.7:1) in the tablet. Methods of making the buccal tablet with enhanced bioavailability and prolonged duration and methods of using the formulation for the treatment of erectile dysfunction are also provided.Type: GrantFiled: March 28, 2023Date of Patent: February 6, 2024Assignee: KING ABDULAZIZ UNIVERSITYInventors: Omar D. Al-hejaili, Khalid M. El-Say, Tarek A. Ahmed, Hossam S. El-Sawy, Fathy I. Abd-Allah
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Patent number: 11884914Abstract: The invention is directed to Haematococcus sp. KAU-01 as well as to a culture medium for Haematococcus sp. KAU-01, and to methods for using this strain to process environmental pollutants such as gases generated by coal-fired plants.Type: GrantFiled: December 7, 2020Date of Patent: January 30, 2024Assignee: King Abdulaziz UniversityInventors: Adnan Jaman Turki, Md. Abu Affan, Salim Marzoog Al-Harbi
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Patent number: 11857623Abstract: The invention is directed to a protein construct comprising a scaffold protein into which an IgE epitope containing motif is inserted or substituted. The protein construct may be used as an antigen, immunogen or vaccine to induce immune responses against IgE in a vaccinated subject thereby reducing the severity of allergic phenomena associated with IgE. The invention is also directed to a method for designing such a protein construct and expressing it using recombinant DNA methods.Type: GrantFiled: August 7, 2020Date of Patent: January 2, 2024Assignee: King Abdulaziz UniversityInventor: Sari Sabban
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Patent number: 11793754Abstract: A nanoemulsion, and a method of preparing the nanoemulsion is disclosed. The nanoemulsion includes sodium hypochlorite (NaOCl), chlorhexidine (CHX), and a self-nanoemulsifying delivery system (SNEDS) which further includes at least one oil, at least one surfactant, and at least one co-surfactant, wherein no parachloroaniline is present in the nanoemulsion after 1 hour at room temperature.Type: GrantFiled: June 16, 2022Date of Patent: October 24, 2023Assignee: King Abdulaziz UniversityInventor: Laila Ahmed Salim Bahammam
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Patent number: 11786537Abstract: Methods of using copper (II) complexes of Formula I to prevent and/or treat coronavirus infections, such as SARS-CoV-2 infections, are provided. In Formula I, Y is NO2 or CH3 and X is a C1 to C20 hydrocarbon which is optionally substituted. The copper (II) complexes bind to an inactivate proteins that are necessary for the virus to successfully establish an infection and reproduce.Type: GrantFiled: February 13, 2022Date of Patent: October 17, 2023Assignee: KING ABDULAZIZ UNIVERSITYInventors: Khadijah M. Al-Zaydi, Mostafa A. Hussien A. Hussein, Ahlam Ibrahim Alsulami
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Patent number: 11780868Abstract: Provided herein are homoleptic metal coordination complexes that induce cellular apoptosis and cell cycle arrest in G0/G1 phase in fungus, such as Candida spp. Also disclosed are methods of inhibiting fungal growth and methods of treating fungal infections using the disclosed compounds. The disclosed compounds exhibit anti-Candida activity against fluconazole resistant and sensitive strains of C. albicans at low concentrations.Type: GrantFiled: April 28, 2023Date of Patent: October 10, 2023Assignee: KING ABDULAZIZ UNIVERSITYInventors: Irfan Ahmad Rather, Majid Rasool Kamli, Khalid Rehman Hakeem, Ahmad Firoz, Jamal S. M. Sabir, Mohmmad Younus Wani, Yong Ha Park, Yan Yan Hor
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Publication number: 20230293705Abstract: The present technology is directed to composition that may be formulated for parenteral administration, where the composition includes a plurality of nanoparticles and optionally a pharmaceutically acceptable carrier. Each nanoparticle of the plurality includes a glatiramoid and one or more of a polyinosine-polycytidylic acid (Poly(I:C)), a plasmid DNA (pDNA), a CpG oligodeoxynucleotide (CpG ODN), or a combination of any two or more thereof.Type: ApplicationFiled: November 9, 2022Publication date: September 21, 2023Applicants: King AbdulAziz University, University of KansasInventors: Cory J. BERKLAND, Nabil Abdulhafiz ALHAKAMY
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Patent number: 11744869Abstract: Provided herein are formulations composed of fish roe wax extract and Nigella sativa oil extract. This oily composition is prepared and used as a treatment for addiction withdrawal symptoms by regulating dopamine and serotonin unbalance in a subject in need thereof. The prepared formulation alleviated the addiction effect of cocaine after daily single dosing of addiction-induced mice.Type: GrantFiled: January 5, 2023Date of Patent: September 5, 2023Assignee: King Abdulaziz UniversityInventors: Alaa Eldin M. Khedr, Maha Ibrahim, Ammar Bayoumi
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Patent number: 11750108Abstract: A 15-level multilevel inverter circuit includes an outer circuit, an inner circuit, a polarity changing circuit and a computing device. The outer circuit and the inner circuit include a plurality of DC voltage supplies. Each DC voltage supply has a positive and a negative terminal. The outer circuit, the inner circuit and the polarity changing circuit include a plurality of unidirectional power switches. Each unidirectional power switch is a transistor with a diode connected in parallel to the transistor. The computing device is configured to provide control signals to the gates of the plurality of the unidirectional power switches of the outer circuit and the inner circuit to add or subtract the voltage of each of inner DC voltage supplies to form square waveforms approximating sinusoidal waveforms, and to the gates of the plurality of the unidirectional power switches of the polarity changing circuit to switch the polarity of the voltage.Type: GrantFiled: December 14, 2020Date of Patent: September 5, 2023Assignee: King Abdulaziz UniversityInventors: Hussain Bassi, Muhyaddin Rawa
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Patent number: 11724937Abstract: A method of dry reforming of methane (CH4) is provided. The method includes contacting at a temperature of 500 to 1000 degree Celsius (° C.) a reactant gas mixture including methane and carbon dioxide (CO2) with a bimetallic supported catalyst. The bimetallic supported catalyst includes a porous catalyst support and a bimetallic catalyst. The porous catalyst support includes aluminum oxide (Al2O3) and magnesium oxide (MgO). The bimetallic catalyst includes nickel (Ni) and copper (Cu) disposed on the porous catalyst support. The method further includes collecting a product gas mixture including hydrogen (H2) and carbon monoxide (CO). The bimetallic supported catalyst includes 8 to 16 weight percent (wt. %) nickel and 2 to 14 wt. % copper, each based on a total weight of bimetallic supported catalyst.Type: GrantFiled: January 11, 2022Date of Patent: August 15, 2023Assignee: King Abdulaziz UniversityInventors: Ibrahim Mustafa Mehedi, Bawadi Abdullah, Mohammad Yusuf, Ubaid M. Al-Saggaf, Ahmed Ubaid Al-Saggaf
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Patent number: 11725219Abstract: The invention is directed to a culture medium for Haematococcus that contains combustion gases like carbon dioxide, carbon monoxide, and oxides of nitrogen or sulfur and which fixes the carbon, nitrogen or sulfur in these combustion gases into biomass and to methods providing superior biomass yields using this culture medium to culture select species of Haematococcus such as Haematococcus sp. KAU-01.Type: GrantFiled: December 7, 2020Date of Patent: August 15, 2023Assignee: King Abdulaziz UniversityInventors: Adnan Jaman Turki, Md. Abu Affan, Salim Marzoog Al-Harbi
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Patent number: 11729307Abstract: A system for controlling smartphones of drivers of moving automobiles including a plurality of smartphones, each smartphone including a GPS unit to record speed and location of smartphone, a driver control application to control access to phone services and social media applications, a low frequency receiver to receive low frequency radio frequency identification, an LF RFID, signal from key fob located within moving automobile, and a computing unit to measure a received signal strength indicator, RSSI, of LF RFID signal, a transmitter to transmit the speed, location, LF RFID signal, and RSSI to a centralized monitor. The centralized monitor includes a computing circuitry to receive the speed, location, LF RFID signal, and RSSI of each smartphone, generate clusters of speeds and locations of smartphones, analyze clusters to determine smartphones located within a particular moving automobile, determine smartphone of driver, and transmit a control signal to the smartphone of the driver.Type: GrantFiled: December 8, 2020Date of Patent: August 15, 2023Assignee: King Abdulaziz UniversityInventors: Fahad Alsolami, Nada Alruhaily
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Patent number: 11721455Abstract: An organic resistor is provided. The organic resistor includes a rubber substrate and a conducting film disposed over the rubber substrate. The conducting film includes a composite of carbon nanotubes and a nickel phthalocyanine complex dispersed in one or more edible oil(s). The present disclosure also relates to a method of making the organic resistor using rubbing-in technology. The organic resistor of the present invention is environmentally friendly and ecologically clean.Type: GrantFiled: January 19, 2023Date of Patent: August 8, 2023Assignee: KING ABDULAZIZ UNIVERSITYInventors: Muhammad Tariq Saeed Chani, Abdullah Mohamed Asiri, Mohammed Muzibur Rahman, Tahseen Kamal, Khasan S. Karimov
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Patent number: 11722051Abstract: Methods and systems for a synchronverter power control during unbalanced grid conditions is disclosed. The system includes a synchronverter coupled with a power supply grid, a power reference generator, configured to receive a terminal voltage measurement vector vt and a current measurement vector i from the synchronverter, and generate an active power Pf and a reactive power Qf, a synchronverter control unit connected to the power reference generator and configured to process the active power Pf and the reactive power Qf and generate an electromotive force (EMF) vector e, and an active and reactive power control unit, connected between the synchronverter control unit and the synchronverter, configured to receive the electromotive force (EMF) vector e and the terminal voltage measurement vector vt, and regulate the current measurement vector i to eliminate power oscillations and current harmonics in the synchronverter during unbalanced grid conditions.Type: GrantFiled: March 3, 2022Date of Patent: August 8, 2023Assignee: KING ABDULAZIZ UNIVERSITYInventors: Saad Pola, Maher Azzouz, Hatem Sindi
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Patent number: 11717804Abstract: An 8-hydroxyquinoline modified halloysite nanoclay (8-HQHNC) is provided. The 8-HQHNC is used in a method of removing heavy metals and/or salt from a solution which includes steps of contacting the solution with 8-HQHNC under conditions suitable for the adsorption of the heavy metals and/or salt to the 8-HQHNC and recovering the 8-HQHNC from the solution.Type: GrantFiled: November 16, 2022Date of Patent: August 8, 2023Assignee: KING ABDULAZIZ UNIVERSITYInventors: Mohamed Abdel Salam, Radwan K. Al-Farawati, Naif Salama Aljohani, Ibrahim I. Shabbaj
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Patent number: 11698351Abstract: A gamma radiography system includes a gamma source holder, a shaft handle attached to the source holder, a source container that surrounds the source holder, a source container cover attached to the source container to receive and slidingly support the shaft handle, a shielded housing that detachably receives the source container, and an extension connected to the shielded housing, such that an opening of the extension covers a beam aperture of the shielded housing. The shaft handle is configured to move the gamma source holder between a non-deployed position, in which the gamma source holder is surrounded by the source container, to a deployed position, in which the gamma source holder extends from the source container into the shielded housing.Type: GrantFiled: July 29, 2022Date of Patent: July 11, 2023Assignee: King Abdulaziz UniversityInventors: Eslam Barzanji, Abdulsalam Alhawsawi, Mohammed Siddig, Mohammed Ali M Alawi
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Publication number: 20230192484Abstract: A method of dry reforming of methane (CH4) is provided. The method includes contacting at a temperature of 500 to 1000 degree Celsius (° C.) a reactant gas mixture including methane and carbon dioxide (CO2) with a bimetallic supported catalyst. The bimetallic supported catalyst includes a porous catalyst support and a bimetallic catalyst. The porous catalyst support includes aluminum oxide (Al2O3) and magnesium oxide (MgO). The bimetallic catalyst includes nickel (Ni) and copper (Cu) disposed on the porous catalyst support. The method further includes collecting a product gas mixture including hydrogen (H2) and carbon monoxide (CO). The bimetallic supported catalyst includes 8 to 16 weight percent (wt. %) nickel and 2 to 14 wt. % copper, each based on a total weight of bimetallic supported catalyst.Type: ApplicationFiled: January 11, 2022Publication date: June 22, 2023Applicant: King Abdulaziz UniversityInventors: Ibrahim Mustafa MEHEDI, Bawadi ABDULLAH, Mohammad YUSUF, Ubaid M. AL-SAGGAF, Ahmed Ubaid AL-SAGGAF