Abstract: The present invention provides compounds comprising at least one unit of formula (1) or (1?) as well as a process for the preparation of the compounds, intermediates of this process, electronic devices comprising the compounds, and the use of the compounds as semiconducting materials.
Type:
Grant
Filed:
October 10, 2019
Date of Patent:
October 3, 2023
Assignees:
CLAP CO., LTD., KING ABDULLAH UNIVERSITY OF SCIENCE & TECHNOLOGY
Inventors:
Daniel Kaelblein, Pascal Hayoz, Hu Chen, Iain McCulloch
Abstract: Derivatives of plumbagin can be selectively cytotoxic to breast cancer cells. Derivative ‘A’ (Acetyl Plumbagin) has emerged as a lead molecule for testing against estrogen positive breast cancer and has shown low hepatotoxicity as well as overall lower toxicity in nude mice model. The toxicity of derivative ‘A’ was determined to be even lower than vehicle control (ALT and AST markers). The possible mechanism of action identified based on the microarray experiments and pathway mapping shows that derivative ‘A’ could be acting by altering the cholesterol-related mechanisms. The low toxicity profile of derivative ‘A’ highlights its possible role'as future anti-cancer drug and/or as an adjuvant drug to reduce the toxicity of highly toxic chemotherapeutic'drugs.
Type:
Grant
Filed:
March 13, 2013
Date of Patent:
February 13, 2018
Assignee:
KING ABDULLAH UNIVERSITY OF SCIENCE & TECHNOLOGY
Inventors:
Sunil Sagar, Mandeep Kaur, Luke E. Esau
Abstract: A system can automatically open at least one window of a vehicle when the vehicle is being submerged in water. The system can include a water collector and a water sensor, and when the water sensor detects water in the water collector, at least one window of the vehicle opens.
Type:
Grant
Filed:
November 3, 2015
Date of Patent:
August 15, 2017
Assignee:
KING ABDULLAH UNIVERSITY OF SCIENCE & TECHNOLOGY
Abstract: A video analytic system includes a depth stream sensor, spatial analysis module, temporal analysis module, and analytics module. The spatial analysis module iteratively identifies objects of interest based on local maximum or minimum depth stream values within each frame, removes identified objects of interest, and repeats until all objects of interest have been identified. The temporal analysis module associates each object of interest in the current frame with an object of interest identified in a previous frame, wherein the temporal analysis module utilizes the association between current frame objects of interest and previous frame objects of interest to generate temporal features related to each object of interest. The analytics module detects events based on the received temporal features.
Type:
Grant
Filed:
October 20, 2014
Date of Patent:
June 7, 2016
Assignee:
KING ABDULLAH UNIVERSITY OF SCIENCE & TECHNOLOGY
Inventors:
Bernard Ghanem, Jens Schneider, Mohamed Shalaby, Usama Elnily
Abstract: A system can automatically open at least one window of a vehicle when the vehicle is being submerged in water. The system can include a water collector and a water sensor, and when the water sensor detects water in the water collector, at least one window of the vehicle opens.
Type:
Grant
Filed:
May 10, 2013
Date of Patent:
December 8, 2015
Assignee:
KING ABDULLAH UNIVERSITY OF SCIENCE & TECHNOLOGY