Abstract: A method of monitoring a patient includes measuring neural respiratory drive using a monitoring device (10), repeating the measurement either continuously or at regular time intervals, and comparing the measurements obtained in order to predict treatment failure and/clinical deterioration and/or re-admission. In embodiments of the invention, the neural respiratory drive is measured by obtaining a measure of the second intercostal space parasternal electromyogram. A monitoring device (10) includes a signal input (20), a processing unit (30), and a output unit (50), and is arranged to measure the neural respiratory drive, store the measured value and compare it to a previously measured value for the neural respiratory drive.

Abstract: The present invention relates to compounds and their use in competitive protein binding assays, for example for use with glycosyl transferase and/or glycoprocessing proteins. The present application also provides kits and apparatuses for use in the assays. In particular, the present invention provides a compound of the formula (I): wherein n is 1, 2 or 3; R1 is selected from —OH, —OPO3H, —OR4, —NHR4, R6; R2 and R3 are each independently selected from —H, —OH, optionally substituted —O-alkyl and —O-alkanoyl; R4 is selected from an optionally substituted mono or polysaccharide, -alkyl, -alkenyl, -alkynyl, and L-Z, where L is a linking agent and Z is a binding agent; R6 is an optionally substituted hydrocarbon group; A is either (i) a substituted heteroaryl group, the substituent on the heteroaryl group having a double bond conjugated to the heteroaryl group, or (ii) a substituted aryl group, the substituent on the aryl group having a double bond conjugated to the aryl group.

Abstract: A diversity transmitter for use in an OFDM transmission protocol which diversity transmitter comprises: a diversity generator (2) for receiving and diversifying OFDM transmit symbols, and outputting diversified OFDM symbol matrices (DOSM), DOSM symbols within each DOSM being divided into at least two primary streams each comprising different DOSM symbols, a transmit processor for receiving said at least two primary streams of DOSM symbols, and for transforming said each DOSM symbol from the frequency domain into the time domain, and outputting time domain OFDM symbols (TDOSs), a cyclic delay circuit (41 . . . 4P) for dividing at least one of said primary streams of TDOSs into at least two branches of identical TDOSs, each branch for supplying a respective spatial channel for transmission to a receiver, the arrangement being such that, in use, said cyclic delay circuit (41 . . . 4P) applies a cyclic time shift to a TDOS symbol in at least one of said branches before transmission.

Abstract: Bioactive glasses may be used as air abrasive agents in methods for treating or preventing dental hard tissue and pulpal disorders, such as dental pain.

Abstract: The present invention relates to the use of a bioactive glass as an air abrasive agent for use in the treatment of dental disorders.