Patents Assigned to King Saud University
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Publication number: 20240148816Abstract: The present disclosure generally relates to herbal compositions. Specifically, the present disclosure relates to herbal composition comprising of Solanum nigrum along with a pharmaceutically acceptable excipients. The present invention also relates to a method of preparing the herbal composition comprising Solanum nigrum and its anti-proliferative effect.Type: ApplicationFiled: November 7, 2022Publication date: May 9, 2024Applicant: King Saud UniversityInventors: Haseeb Ahmad Khan, Rajendra Prasad, Amani Ahmed Alghamdi, Salman Alrokayan
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Publication number: 20240052417Abstract: A non-invasive method for determining fetal gender prior to the second trimester using multiplex polymerase chain reaction to identify target segments of the SRY, DAZ2 and TSPY1 genes which are located on the Y chromosome of a male fetus. A kit for determining gender comprising primers that amplify target segments of the SRY, DAZ2 and TSPY1 genes.Type: ApplicationFiled: August 12, 2022Publication date: February 15, 2024Applicants: Imam Abdulrahman Bin Faisal University, King Saud UniversityInventors: J. Francis BORGIO, Norah Fahad ALHUR, Nourah H. AL QAHTANI, Sayed ABDULAZEEZ, Noor B. ALMANDIL, Entissar Asulaiman ALSUHAIBANI
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Patent number: 11874752Abstract: A method of facilitating cyber inspection of connected and autonomous electrical vehicles using smart charging stations. Accordingly, the method comprises receiving an information associated with a connected and autonomous electrical vehicle (CAEV) connected to a smart charging station, identifying an operation comprising a scanning operation based on the information, generating a request for facilitating the scanning operation comprising a cyber security threats scan, a cyber-attacks scan, an antivirus scan, an antimalware, an anti-ransomware, and a security scan, transmitting the request to a service provider device of a service provider comprising a cyber security provider, receiving a scanning operation information from the service provider device, performing the scanning operation on ECUs of the CAEV for facilitating the cyber inspection of the CAEV using the scanning information, generating a status of the CAEV based on the performing, transmitting the status to a device, and storing the status.Type: GrantFiled: March 21, 2023Date of Patent: January 16, 2024Assignee: King Saud UniversityInventors: Muhammad Khurram Khan, Wazir Zada Khan
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Patent number: 11762969Abstract: The present disclosure provides a method for facilitating biometric recognition. Further, the method includes receiving, using a communication device, a biometric data from a user device. Further, the biometric data includes an eyeball image data. Further, the eyeball image data includes a periocular region image and an iris image. Further, the method includes processing, using a processing device, the biometric data using a machine learning model. Further, the method includes determining, using the processing device, an iris feature based on the processing. Further, the method includes determining, using the processing device, a periocular feature based on the processing. Further, the method includes concatenating, using the processing device, the iris feature and the periocular feature. Further, the method includes generating, using the processing device, an enrolled image data based on the concatenating. Further, the method includes storing, using a storage device, the enrolled image data in a database.Type: GrantFiled: January 12, 2023Date of Patent: September 19, 2023Assignee: King Saud UniversityInventors: Muhammad Khurram Khan, Saiyed Umer, Ranjeet Kumar Rout, Alamgir Sardar
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Publication number: 20230256116Abstract: The present invention relates to a NDG-Mn3O4 nanocomposite comprising a nitrogen doped graphene (NDG) and Mn3O4 nanoparticles. The NDG-Mn3O4 nanocomposite is useful in bimodal performance including photodynamic therapy (PDT) and magnetic resonance imaging (MRI). The NDG-Mn3O4 nanocomposites of the present invention caused significant cell death under laser irradiation, while control and Mn3O4 nanoparticles showed negligible cell death.Type: ApplicationFiled: April 27, 2023Publication date: August 17, 2023Applicant: King Saud UniversityInventors: Haseeb Ahmad Khan, Sara Tariq Alrashood, Mohammed Rafi Shaik, Aishah Ali Ekhzaimy
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Publication number: 20230146437Abstract: The present disclosure pertains to a 3D scaffold for cell growth and proliferation. In particular, the present disclosure provides a method of producing an artificial 3D scaffold to support stem cell growth and later their differentiation, by converting biodegradable amphiphilic copolymers (star polymer) into nanowire scaffolds, through a molecular self-assembly process. The invention also relates to the use of said scaffold for cell culture and/or transplantation.Type: ApplicationFiled: December 30, 2022Publication date: May 11, 2023Applicant: King Saud UniversityInventors: Salman Alrokayan, Fouzi Mouffouk, Haseeb Ahmad Khan, Tajamul Hussain, Salman Alamery, Khalid M. Abu-Salah
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Publication number: 20230087073Abstract: The present disclosure relates generally to anti-cancer pharmaceuticals. More specifically, the disclosure is directed to gold complexes of Formula I with anti-cancer properties. The disclosure also provides a pharmaceutical composition comprising the complexes, a process of synthesizing the complexes and a method of treating cancer. The complexes of the present disclosure have a multi-target approach to cancer therapeutics by inducing cell apoptosis, cytotoxicity, mitochondrial membrane potential depolarization and increasing reactive oxygen species in cancer cells.Type: ApplicationFiled: September 30, 2022Publication date: March 23, 2023Applicant: King Saud UniversityInventors: Haseeb Ahmad Khan, Abdullah Saleh Alhomida, Ali Al-Hoshani, Anvarhusein Abdulkadir Isab
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Patent number: 11501580Abstract: The present disclosure provides a method for facilitating implementing biometric recognition. Further, the method may include receiving two or more biometric images of one or more biometric identifiers of one or more individuals from one or more devices. Further, the two or more biometric images may be in two or more spectrums. Further, the method may include analyzing the two or more biometric images using one or more deep hashing network models. Further, the method may include extracting two or more discriminative deep hashing codes from the two or more biometric images based on the analyzing. Further, the method may include generating a biometric template based on the two or more discriminative deep hashing codes. Further, the method may include generating a biometric key for the one or more biometric identifiers using a fuzzy commitment scheme based on the biometric template. Further, the method may include storing the biometric key.Type: GrantFiled: March 30, 2022Date of Patent: November 15, 2022Assignee: King Saud UniversityInventors: Muhammad Khurram Khan, Tengfei Wu, Leng Lu
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Publication number: 20220339300Abstract: The present disclosure provides HRG-Mn3O4 hybrid nanoparticles. The HRG-Mn3O4 hybrid nanoparticles do not pose any cytotoxicity at normal physiological conditions and therefore they are nontoxic and biocompatible at physiological conditions. The HRG-Mn3O4 hybrid nanoparticles under exposure of laser light cause massive cellular damage indicating their potential use for photodynamic therapy of cancer. The HRG-Mn3O4 hybrid nanoparticles enhance the magnetic resonance signals from cancer cells and exhibit excellent MRI contrast property for tumor imaging and are therefore useful contrast agent.Type: ApplicationFiled: July 12, 2022Publication date: October 27, 2022Applicant: King Saud UniversityInventors: Haseeb Ahmad Khan, Mohammed Rafi Shaik, Sara Tariq Alrashood, Aishah Ali Ekhzaimy
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Publication number: 20210351910Abstract: A system in Elliptic Curve Cryptography (ECC) that offers secure encoding and mapping of a message to the curve E against encryption attacks, such as Chosen Plaintext Attack (CPA) and Ciphertext Only Attack (COA). The system includes, a method to convert the text message to numerical values with manipulation using Initial Vector IV. In addition, the system provides, a method to revert the manipulated values to their original value.Type: ApplicationFiled: May 6, 2020Publication date: November 11, 2021Applicant: King Saud UniversityInventors: Hisham AlMajed, Ahmad AlMogren
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Patent number: 11147848Abstract: The present invention relates to extracts, compounds isolated from Cakile arabica for use in the treatment of ulcer and to pharmaceutical compositions thereof.Type: GrantFiled: March 12, 2019Date of Patent: October 19, 2021Assignee: King Saud UniversityInventors: Awaad Amani Shafeek, Reham Moustafa El-Meligy, Mohammed Sobhy Marzouk, Shroog Mohamed Alotaiby
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Patent number: 11142539Abstract: Mixed ligand phosphinogold(I) complexes as anticancer agents. The gold(I) ion of the complexes is coordinated to a phosphine and a dithiocarbamate or halogen ligand. Also described are a pharmaceutical composition incorporating the phosphinogold(I) complex, a method of synthesizing the phosphinogold(I) complex, and a method of treating cancer. The phosphinogold(I) complexes exhibit potent cytotoxicity against lung, cervical, and liver cancer cells.Type: GrantFiled: March 10, 2020Date of Patent: October 12, 2021Assignees: King Fahd University of Petroleum and Minerals, King Saud UniversityInventors: Anvarhusein A. Isab, Adam Ahmed Abdullah Sulaiman, Ali Alhoshani
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Publication number: 20210284674Abstract: Mixed ligand phosphinogold(I) complexes as anticancer agents. The gold(I) ion of the complexes is coordinated to a phosphine and a dithiocarbamate or halogen ligand. Also described are a pharmaceutical composition incorporating the phosphinogold(I) complex, a method of synthesizing the phosphinogold(I) complex, and a method of treating cancer. The phosphinogold(I) complexes exhibit potent cytotoxicity against lung, cervical, and liver cancer cells.Type: ApplicationFiled: March 10, 2020Publication date: September 16, 2021Applicants: King Fahd University of Petroleum and Minerals, King Saud UniversityInventors: Anvarhusein A. ISAB, Adam Ahmed Abdullah SULAIMAN, Ali ALHOSHANI
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Publication number: 20210284671Abstract: A family of platinum(II) complex with mixed ligands as anticancer agents. The platinum(II) ion is coordinated to dicyclopentadiene and dithiocarbamate ligands. Also described are a pharmaceutical composition incorporating the platinum(II) complex, a methods of synthesizing the platinum(II) complex, and a method of treating cancer. The platinum(II) complexes exhibit potent cytotoxicity against lung and cervical cancer cell lines as well as low nephrotoxicity.Type: ApplicationFiled: March 10, 2020Publication date: September 16, 2021Applicants: King Fahd University of Petroleum and Minerals, King Saud UniversityInventors: Adam Ahmed Abdullah Sulaiman, Ali Alhoshani, Anvarthusein A. Isab
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Patent number: 11117912Abstract: A family of platinum(II) complex with mixed ligands as anticancer agents. The platinum(II) ion is coordinated to dicyclopentadiene and dithiocarbamate ligands. Also described are a pharmaceutical composition incorporating the platinum(II) complex, a methods of synthesizing the platinum(II) complex, and a method of treating cancer. The platinum(II) complexes exhibit potent cytotoxicity against lung and cervical cancer cell lines as well as low nephrotoxicity.Type: GrantFiled: March 10, 2020Date of Patent: September 14, 2021Assignees: King Fahd University of Petroleum and Minerals, King Saud UniversityInventors: Adam Ahmed Abdullah Sulaiman, Ali Alhoshani, Anvarhusein A. Isab
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Patent number: 10967020Abstract: The custard apple peel nanoparticles may be manufactured by extracting custard apple peels in a solvent, spraying the custard apple peel extracts into boiling water under ultrasonic conditions to produce a first mixture, sonicating the mixture, stirring the mixture, and drying the mixture to obtain custard apple peel nanoparticles. In an embodiment, the custard apple peel may be peel of Annona reticulata. In an embodiment, the custard apple peel nanoparticles may have improved antibacterial or antioxidant properties.Type: GrantFiled: April 5, 2019Date of Patent: April 6, 2021Assignee: King Saud UniversityInventors: Hany M. Yehia, Hatem Salama Ali, Ebtesam Mohammed Al Olayan, Manal Fawzy Elkhadragy, Mohamed Fekry Mansour Serag Eldin, Manal Ahmed Awad
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Patent number: 10934175Abstract: The method of producing zinc oxide nanoparticles (ZnO NPs) using red sand includes mixing red sand with water to form an aqueous suspension of red sand, removing the supernatant from the suspension, centrifuging the supernatant and retaining a second supernatant from the centrifuged suspension, dissolving a solution of zinc nitrate in the second supernatant to form a precursor solution, and adding 1M NaOH dropwise to the precursor solution to precipitate the zinc oxide nanoparticles. The precipitate may be washed, dried and calcined to provide the red sand synthesized ZnO NPs. The red sand synthesized ZnO NPs have photocatalytic activity and can be used, for example, to degrade organic dyes in aqueous environments.Type: GrantFiled: December 2, 2019Date of Patent: March 2, 2021Assignee: King Saud UniversityInventors: Manal Ahmed Gasmelseed Awad, Ali Kanakhir Aldalbahi, Khalid Mustafa Osman Ortashi, Taghrid Saad Omar Alomar, Najla Saad Almasoud
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Patent number: 10768363Abstract: The plasmonic infrared optical antenna includes an upper layer of a metallic material (such as gold) capable of supporting a plasmonic electromagnetic field, a thin middle layer of an infrared absorption material, and a bottom supporting layer of a thick substrate. The upper layer has a 2-dimensional periodic array of micron-sized plasmonic antenna cells defined therein. Each antenna cell has the shape of a Bundt baking pan, including a conical antenna horn having an inverted frusto-conical upper portion and a cylindrical stem or lower portion depending from the upper portion. The upper layer includes a post concentrically disposed in the cylindrical lower portion, the post having a conical upper portion extending into the horn, a cylindrical middle portion defining an annular waveguide of 50 nm clearance between the post and the stem of the conical horn, and a conical wedge base embedded in the thin layer of infrared absorption material.Type: GrantFiled: October 23, 2019Date of Patent: September 8, 2020Assignee: King Saud UniversityInventor: Ehab Awad
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Patent number: 10751802Abstract: The method of producing silver nanoparticles using red sand may include the steps of adding red sand to water, mixing the red sand in the water, removing a supernatant from the red sand in water mixture after the mixture has settled, adding sodium hydroxide to the supernatant to form an alkaline solution, adding silver nitrate (AgNO3) to the solution, and isolating a precipitated reaction product including the silver nanoparticles. The silver nanoparticles produced according to this method have antibacterial activity, whether used alone or in combination with standard antibiotics.Type: GrantFiled: October 3, 2019Date of Patent: August 25, 2020Assignee: King Saud UniversityInventors: Manal Ahmed Gasmelseed Awad, Moudi Abdullah Rashed Alwehaibi, Jamilah Hamed Alshehri, Manal Mohammed Alkhulaifi, Noura Saleem Aldosari, Khalid Mustafa Osman Ortashi, Awatif Ahmed Hendi
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Patent number: 10743700Abstract: The curtain rod wall mount is a fixture used in pairs to support opposing ends of a cylindrical curtain rod between opposing walls of a building or window frame. In a first embodiment, the wall mount includes a helical spring disposed between a fixed plug and a movable plug, the spring being coaxially disposed around a guide screw extending between the plugs, the spring assembly being housed in a tubular sleeve that an end of the curtain rod slides into to bear against the movable plug. A second embodiment is similar to the first, but omits the guide screw. In a third embodiment, the wall mount has a wall plate having a threaded stud extending therefrom. The tubular sleeve has a plug with an internally threaded bore in one end that engages the threaded stub, the other end being hollow to receive an end of the curtain rod.Type: GrantFiled: January 16, 2020Date of Patent: August 18, 2020Assignee: King Saud UniversityInventors: Hany Hassan Aly Sayed, Thamer Ali Albahkali