Patents Assigned to King Saud University
  • Patent number: 11142539
    Abstract: Mixed ligand phosphinogold(I) complexes as anticancer agents. The gold(I) ion of the complexes is coordinated to a phosphine and a dithiocarbamate or halogen ligand. Also described are a pharmaceutical composition incorporating the phosphinogold(I) complex, a method of synthesizing the phosphinogold(I) complex, and a method of treating cancer. The phosphinogold(I) complexes exhibit potent cytotoxicity against lung, cervical, and liver cancer cells.
    Type: Grant
    Filed: March 10, 2020
    Date of Patent: October 12, 2021
    Assignees: King Fahd University of Petroleum and Minerals, King Saud University
    Inventors: Anvarhusein A. Isab, Adam Ahmed Abdullah Sulaiman, Ali Alhoshani
  • Publication number: 20210284674
    Abstract: Mixed ligand phosphinogold(I) complexes as anticancer agents. The gold(I) ion of the complexes is coordinated to a phosphine and a dithiocarbamate or halogen ligand. Also described are a pharmaceutical composition incorporating the phosphinogold(I) complex, a method of synthesizing the phosphinogold(I) complex, and a method of treating cancer. The phosphinogold(I) complexes exhibit potent cytotoxicity against lung, cervical, and liver cancer cells.
    Type: Application
    Filed: March 10, 2020
    Publication date: September 16, 2021
    Applicants: King Fahd University of Petroleum and Minerals, King Saud University
    Inventors: Anvarhusein A. ISAB, Adam Ahmed Abdullah SULAIMAN, Ali ALHOSHANI
  • Publication number: 20210284671
    Abstract: A family of platinum(II) complex with mixed ligands as anticancer agents. The platinum(II) ion is coordinated to dicyclopentadiene and dithiocarbamate ligands. Also described are a pharmaceutical composition incorporating the platinum(II) complex, a methods of synthesizing the platinum(II) complex, and a method of treating cancer. The platinum(II) complexes exhibit potent cytotoxicity against lung and cervical cancer cell lines as well as low nephrotoxicity.
    Type: Application
    Filed: March 10, 2020
    Publication date: September 16, 2021
    Applicants: King Fahd University of Petroleum and Minerals, King Saud University
    Inventors: Adam Ahmed Abdullah Sulaiman, Ali Alhoshani, Anvarthusein A. Isab
  • Publication number: 20210283140
    Abstract: A platinum(II) complex of formula (I), or a pharmaceutically acceptable solvate or tautomer thereof, wherein R1 and R2 are each independently a hydrogen, an optionally substituted alkyl, an optionally substituted cycloalkyl, an optionally substituted arylalkyl, or an optionally substituted aryl; or wherein R1 and R2 together form a five-, six-, or seven-membered ring with the nitrogen atoms to which they are attached; and X is a nitrate anion, a hexafluorophosphate anion, a hexafluoroantimonate anion, a trifluoromethanesulfonate anion, a tetrafluoroborate anion, a perchlorate anion, or a halide anion. A pharmaceutical composition containing the platinum(II) complex of formula (I), and a method of treating cancer are also disclosed.
    Type: Application
    Filed: February 1, 2021
    Publication date: September 16, 2021
    Applicants: KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS, KING SAUD UNIVERSITY
    Inventors: Adam Ahmed Abdullah SULAIMAN, Abdul Rajjak SHAIKH, Ali ALHOSHANI, Anvarhusein A. ISAB
  • Patent number: 11117912
    Abstract: A family of platinum(II) complex with mixed ligands as anticancer agents. The platinum(II) ion is coordinated to dicyclopentadiene and dithiocarbamate ligands. Also described are a pharmaceutical composition incorporating the platinum(II) complex, a methods of synthesizing the platinum(II) complex, and a method of treating cancer. The platinum(II) complexes exhibit potent cytotoxicity against lung and cervical cancer cell lines as well as low nephrotoxicity.
    Type: Grant
    Filed: March 10, 2020
    Date of Patent: September 14, 2021
    Assignees: King Fahd University of Petroleum and Minerals, King Saud University
    Inventors: Adam Ahmed Abdullah Sulaiman, Ali Alhoshani, Anvarhusein A. Isab
  • Patent number: 11052379
    Abstract: A mixed metal oxide catalyst includes NiMnO nanoparticles on a TiO2 nanoparticle support. The catalyst may be used to produce biodiesel from waste oils, such as used cooking oils, through a transesterification reaction. The process of producing biodiesel using waste oils using the mixed metal oxide catalyst eliminates a need for quenching, reduces issues related to saponification and glycerol recovery, and allows for easy recovery and reuse of the mixed metal oxide catalyst in an economical and environmentally friendly way.
    Type: Grant
    Filed: July 20, 2020
    Date of Patent: July 6, 2021
    Assignee: KING SAUD UNIVERSITY
    Inventors: Syed Farooq Adil, Mohammed Rafiq Hussain Siddiqui, Saad Hamad Alabbad, Abdurrahman Abdullah Al-Warthan, Mujeeb Yousuf Khan, Mufsir Kuniyil
  • Patent number: 11030912
    Abstract: The interactive Arabic alphabet blocks is a set of blocks for teaching children Arabic letters. Each block interacts with a touch screen to teach the symbol of a letter and its pronunciation. Each interactive Arabic alphabet block includes a front face having an Arabic letter painted and/or engraved thereon. The bottom face of the blocks includes a plurality of raised nubs thereon. The nubs and all faces of the blocks are covered with a conductive mesh or paint. The nubs represent the start and stop locations of each stroke of forming the Arabic letter. When the block is placed on a touch screen of a mobile electronic device, an application on the device detects the nubs and identifies the Arabic letter associated with the location of the nubs. The Arabic letter identified is displayed on the device's screen and played by the device's speaker or headphones.
    Type: Grant
    Filed: September 20, 2018
    Date of Patent: June 8, 2021
    Assignee: KING SAUD UNIVERSITY
    Inventors: Hend Suliaman Al-Khalifa, Sara Al-Siyat, Maram Al-Harthi, Fajer Al-Bakiri
  • Patent number: 11013363
    Abstract: The beverage mixing and dispensing system is a system for producing beverages having a variety of different consistencies, such as those which may be used in the evaluation and treatment of patients with swallowing disorders. The beverage mixing and dispensing system automatically mixes a thickening agent in desired quantities with either water and/or an infused beverage. The beverage mixing and dispensing system may further automatically add beverage modifying agents, such as flavor additives and/or dyes. The resultant mixed beverages are automatically dispensed.
    Type: Grant
    Filed: September 9, 2020
    Date of Patent: May 25, 2021
    Assignee: KING SAUD UNIVERSITY
    Inventors: Nora Alsudairi, Maram Alkahtani, Lamia Alsiddiqi, Raghad Alsarami
  • Patent number: 11006659
    Abstract: A fortified date fruit product includes date fruit sugar and one or more mineral phosphate nanostructures. The mineral phosphate nanostructures can be selected from one or more of calcium phosphate, zinc phosphate, and iron phosphate nanostructures, among others. The mineral phosphate nanostructures can have a particle size ranging from about 5 nm to about 100 nm, e.g., about 5 nm to about 20 nm, about 50 nm to about 100 nm, and about 75 nm to about 100 nm.
    Type: Grant
    Filed: August 21, 2018
    Date of Patent: May 18, 2021
    Assignee: KING SAUD UNIVERSITY
    Inventors: Ali Abdullah Alshatwi, Jegan Athinarayanan, Periasamy Vaiyapuri Subbarayan
  • Patent number: 11001505
    Abstract: The copper oxide nanoparticles synthesized using Rhatany root extract involves preparing the Rhatany root extract by adding powdered Rhatany roots to boiling water, allowing the mixture to soak overnight, and removing any solid residue by filtering to obtain the aqueous extract. The copper oxide nanoparticles are prepared by mixing equal volumes of the aqueous Rhatany root extract and 0.1 M aqueous copper sulfate, heating the mixture at 80° C. for 40 minutes, and adding 1 M sodium hydroxide dropwise to the mixture to precipitate CuO. The precipitate is removed by centrifuge, washed with ethanol, dried, and calcined at 400° C. for 4 hours to obtain the copper oxide nanoparticles. The resulting nanoparticles proved effective in degrading wastewater dyes, showed anticancer activity against human cervical cancer by cell viability assay, and showed antibacterial activity against various strains of bacteria by agar diffusion.
    Type: Grant
    Filed: June 16, 2020
    Date of Patent: May 11, 2021
    Assignee: KING SAUD UNIVERSITY
    Inventors: Ali Aldalbahi, Bushra Ibarahim Alabdullah, Manal Ahmed Gasmelseed Awad, Shaykha Mohammed Alzahly, Zainah Ali Alqahtani, Shorouq Mohsen Alsaggaf, Hessa Abdullah Aljasser, Hind Ali Abdullah Alshehri
  • Patent number: 10995010
    Abstract: A method of synthesizing copper oxide nanoparticles includes preparing a liquid extract of Rumex vesicarius, dissolving copper salt in the liquid extract to provide a solution with copper nanoparticles, adding a base to the solution with copper nanoparticles to form a precipitate including copper oxide nanoparticles. Copper oxide nanoparticles prepared according to the method are effective photocatalysts for degrading organic dyes and antibacterial agents and exhibit anticancer activities.
    Type: Grant
    Filed: June 26, 2020
    Date of Patent: May 4, 2021
    Assignee: KING SAUD UNIVERSITY
    Inventors: Ali Aldalbahi, Raneem Aldawish, Manal Ahmed Gasmelseed Awad, Noura Saleem Aldosari, Reem Hamad Alshathri, Leen Abdullah Aldwihi, Raghad Alammari, Khloud Ibrahim Bin Shoqiran
  • Patent number: 10980688
    Abstract: The hospital bed with pivoting side rail includes a bed frame having a headboard, a footboard and a platform mounted thereon. The side rail has an upper end, a lower end, and first and second longitudinally opposed sides. The lower end of the side rail is pivotally attached to the bed frame, and the upper end of the side rail is releasably attached to the headboard and the footboard. In order to safely and easily deploy and collapse the side rail, first and second adjustable struts are provided, the struts having opposed first and second ends, such that the first ends of the first and second adjustable struts are pivotally attached to the first and second sides of the side rail, and the second ends of the first and second adjustable struts are pivotally secured to the headboard and footboard, respectively.
    Type: Grant
    Filed: March 5, 2020
    Date of Patent: April 20, 2021
    Assignee: KING SAUD UNIVERSITY
    Inventors: Thamer Ali Albahkali, Hany Hassan Aly Sayed
  • Patent number: 10980843
    Abstract: Bee venom nanoparticles and methods of synthesizing bee venom nanoparticles are provided. The bee venom nanoparticles may be synthesized by drying bee venom, suspending the dried bee venom in a solvent to form a first bee venom solution, spraying the first bee venom solution into boiling water under ultrasonic conditions to form a bee venom solution including the bee venom nanoparticles, stirring the bee venom solution including the bee venom nanoparticles, and freeze-drying the bee venom solution. The resulting nanoparticles may be used in pharmaceutical compositions, and may be useful for their antimicrobial activities.
    Type: Grant
    Filed: February 25, 2020
    Date of Patent: April 20, 2021
    Assignee: KING SAUD UNIVERSITY
    Inventors: Reem Atta Alajmi, Nadin Mohamed Moubayed, Manal Ahmed Gasmelseed Awad, Hany Mohamed Yehia, Manal Fawzy Elkhadragy, Ibrahim Abdullah Barakat, Faten Nasser Alsaqabi, Amany Zein Elabedein Mahmoud Elshahidy
  • Patent number: 10982443
    Abstract: The hybrid post-installed anchor for concrete is a structural anchor for installation within a hole formed in concrete. The hybrid post-installed anchor for concrete includes an anchor rod and a plurality of anchor rings mounted on and encircling the anchor rod. Each anchor ring includes a cylindrical ring, having opposed open upper and lower ends, and a plurality of fins secured to an outer surface of the cylindrical ring. Each fin has a fixed edge, which is secured to the outer surface of the cylindrical ring, and a free edge. Each fin projects radially and upwardly, such that each fin is angled with respect to a common central axis of the anchor rod and each anchor ring when the anchor rings are mounted coaxially on the anchor rod. Alternatively, the fins may be formed integrally on the anchor rod, without separate cylindrical rings.
    Type: Grant
    Filed: July 20, 2020
    Date of Patent: April 20, 2021
    Assignee: KING SAUD UNIVERSITY
    Inventors: Husain Abbas, Tarek H. Almusallam, Eid Shaja Alotaibi, Yousef A. Al-Salloum
  • Patent number: 10967020
    Abstract: The custard apple peel nanoparticles may be manufactured by extracting custard apple peels in a solvent, spraying the custard apple peel extracts into boiling water under ultrasonic conditions to produce a first mixture, sonicating the mixture, stirring the mixture, and drying the mixture to obtain custard apple peel nanoparticles. In an embodiment, the custard apple peel may be peel of Annona reticulata. In an embodiment, the custard apple peel nanoparticles may have improved antibacterial or antioxidant properties.
    Type: Grant
    Filed: April 5, 2019
    Date of Patent: April 6, 2021
    Assignee: King Saud University
    Inventors: Hany M. Yehia, Hatem Salama Ali, Ebtesam Mohammed Al Olayan, Manal Fawzy Elkhadragy, Mohamed Fekry Mansour Serag Eldin, Manal Ahmed Awad
  • Patent number: 10959809
    Abstract: A multifunctional dental liner applicator dispenses tooth liner and a stream of air while illuminating the working dental area. The applicator includes a body and a head that is removably attached to a distal end of the body. The head supports a nozzle that is configured to be inserted into a void of a prepared tooth. A liner button on the body controls a valve for dispensing liner out of the nozzle. An air button controls airflow out of openings adjacent the nozzle for drying an area that is receiving liner. Fiber optic fibers extend from a button controlled light source housed in the body to openings adjacent the nozzle for illuminating the working area.
    Type: Grant
    Filed: February 6, 2020
    Date of Patent: March 30, 2021
    Assignee: KING SAUD UNIVERSITY
    Inventor: Sarah Sultan Alangari
  • Patent number: 10954662
    Abstract: The system and method for connecting a square concrete-filled steel tubular column to a reinforced concrete footing includes a short steel pipe partially embedded in the footing, the pipe having a top end having flanges extending radially therefrom, the top end extending into a cavity in the footing having an elliptical top opening and circular base, the flanges extending above the base. An elliptical base plate is welded to the bottom of the tubular steel column, the base plate having a circular opening defined therein and a plurality of spaced flange slots depending therefrom. The bottom end of the column is lowered into the cavity, the elliptical base plate passing through the elliptical opening in the cavity, and the column is rotated 90° to interlock the flanges with the flange slots. The cavity is filled with concrete grout, and the square or rectangular steel column is filled with concrete.
    Type: Grant
    Filed: August 5, 2020
    Date of Patent: March 23, 2021
    Assignee: KING SAUD UNIVERSITY
    Inventors: Husain Abbas, Nadeem A. Siddiqui, Baha M. A. Khateeb, Tarek H. Almusallam, Yousef A. Al-Salloum
  • Patent number: 10954200
    Abstract: An anti-angiogenic compound includes 4-Benzyl-N?-(2-(o-tolyloxy) acetyl) morpholine-2-carbohydrazide (BAMC), having the following structural formula: or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: October 24, 2019
    Date of Patent: March 23, 2021
    Assignee: KING SAUD UNIVERSITY
    Inventors: Yasser Hussein Issa Mohammed, Nabil Ahmed Qassim Al-Zeqri, Ali Mohammed Alsalme, Fahed Ahmed Ali Alharthi, Ismail Khalil Warad, Anas Khaled Alali, Abdelkader M. Zarrouk
  • Patent number: 10955170
    Abstract: The solar heating apparatus has a base box and a main axle mounted on the base box. At least one mirror support arm is mounted orthogonal to the main axle and supports a plurality of mirrors. In a first embodiment, a circular plate on the side of the base box rotates the main axle to bank the mirrors to track azimuth and a belt or chain drive rotates the mirror support arms to track elevation. In a second embodiment, the main axle is a beam mounted on a rotating circular plate on top of the base box to track azimuth and bevel gears drive a belt or chain drive that rotates the mirror support arms to track elevation. In a third embodiment, the mirror support arms are driven to rotate by bevel gears and the main axle through belt or chain drives.
    Type: Grant
    Filed: November 7, 2018
    Date of Patent: March 23, 2021
    Assignees: KING SAUD UNIVERSITY, QUDRA ENERGY COMPANY
    Inventors: Yousef Abdullah Almotlaq, Mazen Abdullah Baabbad, Hany Abdulrahman Alansary, Essam Abdulaziz Al Ammar
  • Patent number: D915593
    Type: Grant
    Filed: November 16, 2018
    Date of Patent: April 6, 2021
    Assignee: KING SAUD UNIVERSITY
    Inventors: Mohammad Ahmad Alenezi, Mohammad Ibraheem Alobaida