Abstract: Methods, probe sets, kits, and compositions for gene deletion assays are disclosed. In some embodiments, the methods relate to preparing probes for a deletion assay, performing a deletion assay, or optimizing a deletion assay. In some embodiments, the methods and probe sets can provide reduced artifactual deletion frequency, for example, when analyzing samples subject to truncation artifacts. In some embodiments, the methods and probe sets can distinguish between small and large deletions.

Abstract: There are provided novel synthetic stool preparations comprising bacteria isolated from a fecal sample from a healthy donor. The synthetic stool preparations are used for treating disorders of the gastrointestinal tract, including dysbiosis, Clostridium difficile infection and recurrent Clostridium difficile infection, prevention of recurrence of Clostridium difficile infection, treatment of Crohn's disease, ulcerative colitis, irritable bowel syndrome, inflammatory bowel disease, and diverticular disease, and treatment of food poisoning such as salmonella. Methods of preparation and methods of use of the synthetic stool preparations are also provided.

Abstract: A method of differentiating between supraventricular tachyarrhythmia (SVT) and ventricular tachyarrhythmia (VT) is disclosed. A post pacing interval (PPI) is determined based on a biomarker dataset. The post pacing interval is statistically analyzed relative to a threshold to differentiate between SVT and VT. A further method of differentiating between SVT and VT is disclosed. A PPI is determined based on a biomarker dataset. A tachycardia cycle length (TCL) is also determined based on the biomarker dataset. A difference of the PPI minus the TCL is statistically analyzed relative to a threshold to differentiate between SVT and VT. A non-transitory computer readable medium and a system are also disclosed for differentiating between SVT and VT.

Abstract: A method of colon cleansing that provides superior cleansing. In an embodiment, superior cleansing of the right colon is provided. In an embodiment, a stimulant laxative is consumed at least two days prior to the day for which maximum cleansing is desired, and an osmotic purgative is consumed one day prior to the day for which maximum cleansing is desired. A regimen that administered PICO-SALAX® plus BISACODYL™ was superior in cleansing the right colon compared to PICO-SALAX® alone, and when compared to Oral Sodium Phosphate. Patient tolerability and safety were excellent.