Abstract: A non-transitory computer-readable recording medium storing a computer program, the computer program comprising: a selecting module configured to select, from among a plurality of biopotential signals, a biopotential signal containing a high proportion of a maternal cardiac potential signal component; an independent component analysis module configured to perform independent component analysis on the plurality of biopotential signals; a periodic signal detection module configured to detect, as a first peak time signal, a signal having periodic peaks from a biopotential signal and to detect, as second peak time signals, one or more signals having periodic peaks among signals output from the independent component analysis module; and an output signal selecting module configured to select from among the one or more second peak time signals a signal having peak times different from those of the first peak time signal.

Abstract: An image sensor and an image sensing method can obtain image signals with a high S/N ratio in a high-speed image pickup operation. Signal charges are input to input transfer stage 31 of CCD memory 30. Final transfer stage 32 is formed so as to be connected to the input transfer stage 31 and able to transfer signal charges to the input transfer stage 31. In an accumulation mode, read gate 42 and drain gate 40 are not turned on and the next transfer operation of the CCD memory 30 is conducted. The accumulated signal charges are transferred on a stage by stage basis and the signal charges obtained at the first image pickup timing are transferred again straightly to the input transfer stage 31. In this state, the signal charges obtained newly at photoelectric conversion section 20 at the next image pickup timing are injected into the input transfer stage 31 by way of input gate 21.

Abstract: Provided are a hard tissue restoration material, which is excellent in hard tissue restoration ability, extremely effective in promoting recalcification of dental enamel, and excellent in protection properties and aesthetic properties, and a hard tissue restoration method. The hard tissue restoration material according to the present invention is a biocompatible ceramic film with flexibility and pliability that is obtained, for example, by immersing a substrate, having the biocompatible ceramic film formed thereon, in a solvent, which does not dissolve the biocompatible ceramic but dissolves at least a portion of the substrate, to dissolve or separate the substrate. Also, with the hard tissue restoration method according to the present invention, the hard tissue restoration material according to the present invention is bonded to or wound around a hard tissue defect site.

Abstract: A biocoke producing apparatus has a reaction vessel that has a preset temperature range and pressure range for, without carbonizing of the pulverized biomass, inducing a pyrolytic or thermal curing reaction of lignin and hemicellulose thereof. The reaction vessel has a pressurization device for pressurizing to the pressure range, a heating device for heating to the temperature range in the state of the pressurization and a cooling device for cooling after maintaining of the above state. Multiple reaction vessels are provided. A pulverization delivery conveyor is provided superior to these reaction vessels, and each of the multiple reaction vessels is connected via a connection tube to the conveyor. The connection tube is provided with a pulverizate charging device for charging a given amount of pulverized biomass in accordance with a timing of pulverizate charging to the reaction vessels.

Abstract: The present invention provides a flexible, biocompatible transparent sheet (8) which has high biocompatibility and a high ability to adsorb a biologically relevant substance, which can be used as a novel biomaterial, and which can be used to observe the propagation, differentiation, and/or the like of living cells in real time. The biocompatible transparent sheet (8) is produced in such a manner that a biocompatible ceramic film (2) is formed on a substrate (1) soluble in a solvent (11) incapable of dissolving biocompatible ceramics by using exemplary a laser ablation process, the substrate (1) depositing the film (2) is dipped in the solvent (11) and dissolved off, and the isolated film (2) is then dried. The biocompatible transparent sheet (8) is utilizable of producing a flexible cultured cell sheet which can be directly transplanted to an affected area. The cell sheet can be prepared in such a manner that cells are seeded on the biocompatible transparent sheet (8) and then propagated.

Abstract: An apparatus and process for producing biocoke usable as a substitute fuel for coal coke from biomass as a raw material. The apparatus comprises pulverizing means for pulverizing a biomass raw material attributed to photosynthesis; heating means for heating to the temperature range in which the hemicellulose of the pulverized biomass raw material is pyrolyzed so as to exhibit bonding effects; pressurization means for, in the state of the heating, pressurizing to the pressure range in which the lignin of the pulverized biomass exhibits a thermal curing reaction and maintaining the pressure; and cooling means for cooling after maintaining the state of the pressurization. The apparatus further comprises temperature detecting means provided at the exit end of the region being heated by the heating means and regulation means for judging a reaction terminal point in accordance with the result of the temperature detection and regulating the timing for transfer from heating to cooling.

Abstract: Amino acid sequences of an enzyme involved in pyrethrin biosynthesis and a base sequence of the gene thereof; constructing vectors bearing the gene and transformants; and extractable from plant bodies producing pyrethrin by applying such creative techniques to plant bodies with faster growth aiming to provide a method to efficiently produce pyrethrin. A gene encoding a protein consisting of the amino acid sequence of SEQ ID NO: 1. A protein consisting of the amino acid sequence of SEQ ID NO: 2.

Abstract: Disclosed are a method of detecting the presence or absence of a single nucleotide polymorphism of a gene, for prediction of the risk of developing drug-induced lung injury, or for improving a therapeutic method, and a kit for carrying out the detection method. The detection method is characterized by comparing an ABCB1 gene in a biological sample with a wild-type ABCB1 gene to detect the presence or absence of a single nucleotide polymorphism in the ABCB1 gene in the biological sample, in particular, by determining the nucleotide at position 3751 of the CDS of the ABCB1 gene. The kit comprises an oligonucleotide probe which specifically binds to a single nucleotide polymorphism in an ABCB1 gene under selective binding conditions, or an oligonucleotide primer which amplifies a nucleic acid sequence comprising a single nucleotide polymorphism in an ABCB1 gene.

Abstract: A plug for a container capable of improving air-tightness and liquid-tightness is provided. A plug includes a first split piece having a cylindrical first fitting portion to be mounted on an opening portion of a container body and fitted to an opening portion space of the opening portion, an end wall which blocks one end of the first fitting portion, and a first flange portion extending outwardly in a radial direction of the first fitting portion from the other end thereof; and a second split piece having a second fitting portion which is fitted to the first fitting portion of the first split piece and forms a closed space between the end wall and the second fitting portion and a second flange portion extending outwardly in a radial direction of the second fitting portion therefrom.

Abstract: A composition for promoting lacrimal secretion which can be used safely and effectively in the lacrimal secretion promoting therapy, not in the conventional supplemental therapy of lacrimal fluid components is provided. The composition for promoting lacrimal secretion comprising a peptide derivative represented by the formula (I): and a contact lens which retains and/or contains the composition are provided.

Abstract: (Problems) To provide an integrated circuit having the wiring structure including pads with a small wiring area and capable of highly integrating elements, a solid image pickup element having the wiring structure, and an imaging device having the solid image pickup element.

Abstract: Disclosed is a detector for chemical sensor devices, the detector being improved in detection sensitivity. Also disclosed is use of such a detector for chemical sensor devices. Specifically, disclosed is a detector for chemical sensor devices by which a substance to be measured is detected by adsorbing the substance contained in a medium on the surface thereof. The detector includes an adsorption layer containing hydroxyapatite or a substituted apatite obtained by substituting a part of elements in hydroxyapatite on a surface which is used for detecting the substance to be measured. Such a detector is greatly improved in detection sensitivity, and thus able to detect a very small amount of a chemical substance.

Abstract: A method is provided which can efficiently remove conidia and microbe or the like of a phytopathogen from air and does not cause generation of ozone originated from discharge or so, thereby preventing occurrence of a plant disease without damaging a plant. There are also provided a flying organism removing apparatus and a plant protecting apparatus which can adequately capture flyable organisms, such as spores of a phytopathogen and/or small vermin, by applying an electrostatic field to the flyable organisms. An electrostatic field generated by dielectric polarization is applied to flyable organisms.

Abstract: A method of producing biocokes in which pulverized biomass is fed and pressed in a reaction container is provided, wherein the pulverized biomass in a substantially-packed state is pressure-formed while being heated in a temperature range and a pressure range to obtain a semi-carbonized solid matter or pre-semi-carbonized solid matter and then cooled to produce biocoke. The method may includes a filling step; a reaction step; heating the pulverized biomass by means of a heating device to the temperature range and keeping such state for a prescribed period of time to form a shaped matter of the pulverized biomass in the reaction container, and then cooling the shaped matter by switching from the heating device to a cooling device; and an ejecting step.

Abstract: A solidified biomass consisting of semi-carbonized or pre-semi-carbonized solid matter is pressure-formed from raw biomass material while being heated and has a maximum compressive strength of 60-200 MPa and calorific value of 18-23 MJ/kg. A method for producing the solidified biomass: includes crushing raw biomass material; loading a barrel with the crushed raw biomass material; inserting a pressure applying piston into a hollow of the barrel; pressure-forming the crushed raw biomass materials by applying pressure with the pressure applying piston while heating the material; obtaining semi-carbonized or pre-semi-carbonized solid matter by retaining constant time of the heating and the pressurizing; cooling the semi-carbonized or pre-semi-carbonized solid matter while maintaining pressure to obtain a cooled solid; and taking out and drying the cooled solid, wherein the pressure applying piston and the hollow of the barrel have very small clearance between their outer and inner peripheries.

Abstract: An antitumor agent which is not easily excreted from tumor cells and is suitable for a topical treatment. Specifically disclosed is a rotaxane compound with contains a compound represented by chemical formula 1 as the base structure. (In chemical formula 1, m?2, n?3, and X represents an anionic molecule or an anionic atom.

Abstract: This invention relates to an antitumor agent comprising carboplatin and a combination drug of tegafur/gimeracil/oteracil potassium to be administered to a cancer patient selected according to an expression level of thymidylate synthase gene.

Abstract: The present invention relates to an enzyme determining amino acid sequences of an enzyme involved in pyrethrin biosynthesis and a base sequence of the gene thereof; constructing vectors bearing the gene and transformants; and extractable from plant bodies producing pyrethrin by applying such creative techniques to plant bodies with faster growth aiming to provide a method to efficiently produce pyrethrin; and the enzyme is a gene encoding a protein of the following (i) or (ii): (i) a protein consisting of an amino acid sequence shown in Sequence No. 1; or (ii) a protein consisting of an amino acid sequence including one or more of a substitution, deletion, insertion, and/or addition of amino acid in the amino acid sequence shown in Sequence No. 1, in which the protein exhibits activity of pyrethrin biosynthetic enzyme.

Abstract: The present invention relates to an enzyme determining amino acid sequences of an enzyme involved in pyrethrin biosynthesis and a base sequence of the gene thereof; constructing vectors bearing the gene and transformants; and extractable from plant bodies producing pyrethrin by applying such creative techniques to plant bodies with faster growth aiming to provide a method to efficiently produce pyrethrin; and the enzyme is a gene encoding a protein of the following (i) or (ii) or (iii): (i) a protein consisting of an amino acid sequence shown in Sequence No. 1; or (ii) a protein consisting of an amino acid sequence shown in Sequence No. 5, or a protein consisting of an amino acid sequence shown in Sequence No. 6, or a protein consisting of an amino acid sequence shown in Sequence No. 7, or a protein consisting of an amino acid sequence shown in Sequence No.

Abstract: A method is provided which can efficiently remove conidia and microbe or the like of a phytopathogen from air and does not cause generation of ozone originated from discharge or so, thereby preventing occurrence of a plant disease without damaging a plant. There are also provided a flying organism removing apparatus and a plant protecting apparatus which can adequately capture flyable organisms, such as spores of a phytopathogen and/or small vermin, by applying an electrostatic field to the flyable organisms. An electrostatic field generated by dielectric polarization is applied to flyable organisms.