Patents Assigned to KisoJi Biotechnology Inc.
  • Binding agents targeting TROP2-expressing tumor cells
    Patent number: 12275799
    Abstract: The present disclosure generally relates to binding agents, such as antibodies and antigen binding fragments thereof, that are capable of binding to trophoblast cell surface antigen-2 (TROP2). Also disclosed herein are binding agents that are capable of targeting TROP2-expressing tumor cells and their use for the treatment of cancer. Single domain antibodies that specifically binds to amino acid residues of the extracellular domain of TROP2 are provided.
    Type: Grant
    Filed: May 14, 2024
    Date of Patent: April 15, 2025
    Assignee: KisoJi Biotechnology Inc.
    Inventors: Wenyang Hou, Shugang Yao, Luis Da Cruz, David S. Young
  • BINDING AGENTS TARGETING TUMORS AND/OR IMMUNE CELLS
    Publication number: 20240166739
    Abstract: The present disclosure generally relates to binding agents that are capable of targeting tumor cells and/or immune cells. The binding agents of the present disclosure comprise one or more antigen binding domains of heavy chain antibodies (HcAb) which are capable of binding to DR2, to PD-1 and/or to CD47. The binding agents of the present disclosure may be in the form of monomers or multimers and may be monospecific or multispecific.
    Type: Application
    Filed: March 25, 2022
    Publication date: May 23, 2024
    Applicant: KisoJi Biotechnology Inc.
    Inventors: Shugang YAO, Richard WARGACHUCK, Wenyang HOU, Luis DA CRUZ, David S. YOUNG