Abstract: The present invention relates to a method of preparing an anthocyanin oligomer using a coenzyme derived from an Aspergillus sp. strain, and more particularly to a method of preparing an anthocyanin oligomer by fermenting an anthocyanin monomer with a coenzyme of Aspergillus niger, which is a kind of Aspergillus sp. strain. According to the present invention, in order to overcome contamination problems during the culturing process using Aspergillus niger, a coenzyme of Aspergillus niger is extracted and the fermentation process is performed using the same, whereby an anthocyanin oligomer characterized by reduced concern of contamination and superior radical-scavenging effects, compared to existing anthocyanin monomers, can be produced.
Type:
Grant
Filed:
July 26, 2018
Date of Patent:
September 15, 2020
Assignee:
KITTO LIFE
Inventors:
Pyo-Jam Park, Tuk-Rai Jeong, Hyun-Pil Yang, Jin Woo Hwang
Abstract: The present invention relates to a method of preparing an anthocyanin oligomer using a coenzyme derived from an Aspergillus sp. strain, and more particularly to a method of preparing an anthocyanin oligomer by fermenting an anthocyanin monomer with a coenzyme of Aspergillus niger, which is a kind of Aspergillus sp. strain. According to the present invention, in order to overcome contamination problems during the culturing process using Aspergillus niger, a coenzyme of Aspergillus niger is extracted and the fermentation process is performed using the same, whereby an anthocyanin oligomer characterized by reduced concern of contamination and superior radical-scavenging effects, compared to existing anthocyanin monomers, can be produced.
Type:
Application
Filed:
July 26, 2018
Publication date:
November 15, 2018
Applicant:
KITTO LIFE
Inventors:
Pyo-Jam Park, Tuk-Rai Jeong, Hyun-Pil Yang, Jin Woo Hwang
Abstract: Disclosed are low-molecular weight, water-soluble chitosan nanoparticles with folic acid conjugated thereto as a target ligand and a preparation method thereof. The nanoparticles can be simply prepared since the strong reactivity of the chitosan allows folic acid to be readily introduced thereinto. Also, the folic acid-conjugated, low-molecular weight, water-soluble chitosan nanoparticles can be useful as gene carriers because they are of low or zero-toxicity, have sizes suitable for use as gene carriers, can readily form complexes with DNA, allow high gene expression rates, and are excellent in targeting tumor cells which are rich in folic acid receptors.
Type:
Application
Filed:
November 14, 2007
Publication date:
February 18, 2010
Applicant:
KITTO LIFE
Inventors:
Jae Woon Nah, Teok Rae Jung, Mi Kyeong Jang, Dong Gon Kim, Sun Heang Heo