Patents Assigned to KLEO PHARMACEUTICALS, INC.
  • Antibody-recruiting molecules for the treatment of cancer
    Patent number: 10780084
    Abstract: The present invention relates to chimeric (including bifunctional) compounds, compositions comprising those compounds and methods of treating cancer in a patient or subject, especially including metastatic and other cancers where cancer cells exhibit overexpression (heightened expression) of cell surface urokinase-type plasminogen activator receptor (urokinase receptor) compared to normal (non-cancerous) cells.
    Type: Grant
    Filed: August 3, 2017
    Date of Patent: September 22, 2020
    Assignees: YALE UNIVERSITY, KLEO PHARMACEUTICALS, INC.
    Inventors: David Spiegel, H. Marie Loughran, Jeffrey C. Pelletier, Allen B. Reitz, Matthew Ernest Welsch