Abstract: An imaging method for radiologically guiding an instrument during medical interventions on an object comprising: providing a first image of said object followed by providing updated images on-the-fly during the intervention to an operator by measuring an undersampled set of projections of said object and reconstructing said updated image based on changes between said first image or an update of said first image and said undersampled set of projections. The invention further relates to particular uses of the method and a system for radiologically guiding medical interventions on an object, comprising means to provide a first image of the object; an imaging apparatus measuring undersampled sets of projections; processing means in communication with the imaging apparatus for providing updated images on-the-fly during the intervention by reconstructing said updated image based on changes between said first image or an update of said first image and said undersampled set of projections.