Abstract: The present disclosure describes a capsule inhaler. The capsule inhaler includes a main body including an inner cavity, a mouth section coupled to or integral with the main body and in fluid communication with the inner cavity, an actuator coupled to the main body, at least four longitudinally spaced apart nozzles residing within the main body positioned and configured to direct airflow into the inner cavity, and a cover coupled to the main body. The inner cavity is sized and configured to receive a capsule containing a dry powder formulation. One or more of the inner cavity, elongate member, and cover each are configured to engage with the capsule when inserted into the inner cavity and assist in separating the capsule to release the dry powder formulation into the inner cavity of the inhaler for inhalation by a subject.