Abstract: A plume cleaning system for a toilet is integrated with a toilet. In one example, a plume cleaner assembly adjacent to a toilet seat is independently removable with respect to the toilet seat. The plume cleaner assembly may include a plume cleaner, apertures, and a fan positioned to draw plume air through the plurality of apertures for treatment by the plume cleaner and expel the treated plume air out of the plume cleaner assembly in a direction at an angle to the apertures. In another example, a plume cleaner assembly with the toilet seat may include at least a fan, an electrostatic collector, and a mist generator. In another example, a plume cleaner assembly is integrated in a tank of the toilet to generate a sanitization fluid that is channeled into the toilet bowl through an overflow tube and/or rim channels.