Patents Assigned to Kochi University
  • Publication number: 20240026308
    Abstract: The objective of the present invention is to provide a novel bacteriophage useful for treating bacterial endophthalmitis and a therapeutic agent for bacterial endophthalmitis comprising the novel bacteriophage. The therapeutic agent for bacterial endophthalmitis according to the present invention is characterized in comprising 1 or more bacteriophages selected from the group essentially consisting of Myoviridae Spounavirinae phiEF7H (accession number: NITE BP-02886), Myoviridae Spounavirinae phiEF19G (accession number: NITE BP-02887), Myoviridae Spounavirinae phiEF14H1 (accession number: NITE BP-02888), and mutants thereof.
    Type: Application
    Filed: September 8, 2023
    Publication date: January 25, 2024
    Applicant: National University Corporation Kochi University
    Inventors: Ken FUKUDA, Shigenobu MATSUZAKI, Atsuki FUKUSHIMA, Masanori DAIBATA, Jumpei UCHIYAMA
  • Patent number: 11304658
    Abstract: The method for diagnosing cerebrospinal fluid hypovolemia includes injecting saline into a subdural space of a subject in a decubitus position, raising an upper body of the subject, and then determining whether the subject has headache or not, or headache of the subject is relieved or not.
    Type: Grant
    Filed: August 9, 2019
    Date of Patent: April 19, 2022
    Assignee: National University Corporation Kochi University
    Inventors: Eiichi Nakai, Tetsuya Ueba
  • Patent number: 10349886
    Abstract: [Problem] To provide an artery visualization device capable of very appropriately visualizing a to-be-punctured artery and an artery imaging device used for the artery visualization device.
    Type: Grant
    Filed: May 28, 2013
    Date of Patent: July 16, 2019
    Assignee: National University Corporation Kochi University
    Inventors: Takayuki Sato, Tatsumi Ike
  • Patent number: 10174111
    Abstract: According to the present disclosure there are provided compositions and methods for treating malignant tumors, including an anti-LSR (lipolysis stimulated lipoprotein receptor) antibody that comprises the presently disclosed antibody heavy and light chain complementarity determining region (CDR) sequences, or an antigen-binding fragment thereof, or a functional equivalent thereof. Further provided for treating an LSR-positive malignancy is an LSR antagonist or an LSR inhibitor such as a nucleic acid. Therapeutic administration of the anti-LSR antibody to a subject having an LSR-positive malignant tumor is also described.
    Type: Grant
    Filed: December 25, 2014
    Date of Patent: January 8, 2019
    Assignee: National University Corporation Kochi University
    Inventors: Tetsuji Naka, Satoshi Serada, Minoru Fujimoto, Masayoshi Toyoura, Yuji Shoya
  • Patent number: 10077316
    Abstract: The present invention relates to an esophageal cancer marker and application thereof. The present invention relates to: a marker that includes Glypican-1 or an expression product thereof, or a fragment or derivative thereof, and serves to identify esophageal cancer; a detection agent that includes a substance that binds to Glypican-1 or an expression product thereof; and a composition that includes a Glypican-1 inhibitor and serves to prevent or treat esophageal cancer. Herein, Glypican-1 can be SEQ ID NO: 1 (nucleic acid sequence) or SEQ ID NO: 2 (amino acid sequence), or an equivalent thereof.
    Type: Grant
    Filed: December 25, 2014
    Date of Patent: September 18, 2018
    Assignee: National University Corporation, Kochi University
    Inventors: Tetsuji Naka, Satoshi Serada, Minoru Fujimoto, Masayoshi Toyoura, Yuji Shoya
  • Patent number: 10058847
    Abstract: A titanium-oxide catalyst containing catalytic metal shows catalysis under high temperature conditions. A titanium-oxide catalyst contains a titanium-oxide nanoparticle assembly and ruthenium particles. The titanium-oxide nanoparticle assembly is an assembly of titanium-oxide nanoparticles, which are nanoparticles of titanium oxide. The ruthenium particles have a smaller particle diameter than the titanium-oxide nanoparticle assembly and the titanium-oxide nanoparticles. The ruthenium particles are dispersed and supported on a surface of the titanium-oxide nanoparticle assembly.
    Type: Grant
    Filed: March 17, 2016
    Date of Patent: August 28, 2018
    Assignees: Nippon Pillar Packing Co., Ltd., Kochi University of Technology
    Inventors: Kazuya Kobiro, Masataka Otani, Keiichiro Moriwaki, Yukimi Hayashi
  • Patent number: 10010872
    Abstract: A titanium-oxide catalyst containing catalytic metal shows catalysis under high temperature conditions. A titanium-oxide catalyst contains a titanium-oxide nanoparticle assembly and ruthenium particles. The titanium-oxide nanoparticle assembly is an assembly of titanium-oxide nanoparticles, which are nanoparticles of titanium oxide. The ruthenium particles have a smaller particle diameter than the titanium-oxide nanoparticle assembly and the titanium-oxide nanoparticles. The ruthenium particles are dispersed and supported on a surface of the titanium-oxide nanoparticle assembly.
    Type: Grant
    Filed: March 17, 2016
    Date of Patent: July 3, 2018
    Assignees: Nippon Pillar Packing Co., Ltd., Kochi University of Technology
    Inventors: Kazuya Kobiro, Masataka Otani, Keiichiro Moriwaki, Yukimi Hayashi
  • Patent number: 9900484
    Abstract: A method includes the steps of emitting infrared light of a predetermined wavelength to an object, receiving infrared light of a predetermined wavelength different from the infrared light emitted from the object, and adjusting white balance of an image output from a camera at this time, thereby showing the incident infrared light as white. The method further includes the steps of emitting white visible light to the object from an RGB light source, receiving visible light emitted from the object, and adjusting the intensity of the RGB light source for each of R, G, and B, thereby adjusting white balance of a captured image.
    Type: Grant
    Filed: July 22, 2011
    Date of Patent: February 20, 2018
    Assignees: Semiconductor Components Industries, LLC, National University Corporation Kochi University
    Inventors: Kazuaki Kojima, Takashi Tanimoto, Takayuki Sato
  • Publication number: 20170362737
    Abstract: A method of producing an apatite crystal includes the steps of preparing an apatite single crystal expressed by the general formula M25(PO4)3X (M2 being at least atomic element selected from the group consisting of divalent alkaline-earth metals and Eu, and X is at least one atomic selected from the group consisting of halogens); placing the apatite single crystal into a space controllable to a predetermined atmosphere; supplying water vapor into the space; and heating such that the atmosphere in the space is within a 1000° C. to 1400° C. range.
    Type: Application
    Filed: June 14, 2017
    Publication date: December 21, 2017
    Applicants: Koito Manufacturing Co., Ltd., Kochi University
    Inventors: Yu SHINOMIYA, Kazumichi YANAGISAWA, Masoud Sakaki
  • Patent number: 9772286
    Abstract: It is to provide a method for detecting urothelial cancer simply and with high accuracy. It is a method for detecting urothelial cancer comprising administering 5-aminolevulinic acid (ALA), a derivative thereof, or a salt of these to a test subject, collecting urine from the test subject, and detecting the presence of fluorescence or amount of fluorescence in the collected urine.
    Type: Grant
    Filed: June 20, 2011
    Date of Patent: September 26, 2017
    Assignees: SBI Pharmaceuticals Co., Ltd., National University Corporation Kochi University
    Inventors: Keiji Inoue, Taro Shuin, Mutsuo Furihata, Yoshihiko Hirao, Tohru Tanaka
  • Patent number: 9707196
    Abstract: A method for treating side effects of anticancer agent includes administering to a subject in need thereof a prophylactic and/or therapeutic agent containing a therapeutically effective amount of a compound shown by the following Formula (I): R1—NHCH2COCH2CH2COOR2??(I) wherein R1 represents a hydrogen atom or an acyl group, and R2 represents a hydrogen atom, a linear or branched alkyl group, a cycloalkyl group, an aryl group, or an aralkyl group, or a salt thereof.
    Type: Grant
    Filed: October 5, 2012
    Date of Patent: July 18, 2017
    Assignees: SBI Pharmaceuticals Co., Ltd., National University Corporation Kochi University
    Inventors: Tohru Tanaka, Kyoko Tsuchiya, Masahiro Ishizuka, Motowo Nakajima, Hitoshi Nakagawa, Taro Shuin, Keiji Inoue, Hideo Fukuhara, Masayuki Tsuda, Mutsuo Furihata
  • Patent number: 9363196
    Abstract: The present invention is provided with: a data-driven processor comprising at least a firing control which determines whether or not firing conditions have been met by determining whether or not all packets necessary for instruction execution have been received when a packet that convey a part of partitioned data to be processed has been input, and a data processing unit for performing processing corresponding to the packets transmitted from the firing control if the firing conditions have been met; a power supply circuit for supplying power to the data-driven processor; and overload avoidance means for refusing input of the packets to the data-driven processor, if a determination has been made that a data processing load in the data-driven processor may reach an overloaded state in which the data processing may stall, on the basis of current consumption in the data-driven processor. Accordingly, power consumption in a networking system is reduced.
    Type: Grant
    Filed: July 9, 2012
    Date of Patent: June 7, 2016
    Assignees: University of Tsukuba, Kochi University of Technology, Tokai University
    Inventors: Hiroaki Nishikawa, Shuji Sannomiya, Makoto Iwata, Hiroshi Ishii, Keisuke Utsu
  • Patent number: 9303056
    Abstract: The objective of the present invention is to provide a monomer for RNA synthesis which can be efficiently produced and therefore by which the producing cost of RNA can be remarkably decreased, and a method for efficiently producing the monomer in a small number of steps. In addition, the objective of the present invention is also to provide a method by which RNA can be efficiently produced even when a approximately stoichiometry amount of the monomer for RNA synthesis is used. The monomer for RNA synthesis according to the present invention is represented by the following formula (I) or (I?): wherein R1 is a protective group of the hydroxy group and R2 is an alkyl group or the like.
    Type: Grant
    Filed: July 25, 2013
    Date of Patent: April 5, 2016
    Assignee: Kochi University
    Inventor: Masanori Kataoka
  • Patent number: 9193604
    Abstract: This invention provides a fine particle composite comprising fine particles of a sulfide or sulfide complex comprising at least one element selected from the group consisting of molybdenum (Mo), rhodium (Rh), ruthenium (Ru), and rhenium (Re) and conductive fine particles via a step of preparing a solvent mixture from a compound containing conductive carbon powder, at least one compound containing an element selected from among molybdenum (Mo), rhodium (Rh), ruthenium (R), and rhenium (Re), and sulfur (S) and a step of conducting a hydrothermal or solvothermal reaction at a pressure and temperature that convert the solvent mixture into a supercritical or subcritical water or solvent.
    Type: Grant
    Filed: September 12, 2008
    Date of Patent: November 24, 2015
    Assignees: Toyota Jidosha Kabushiki Kaisha, National University Corporation Kochi University
    Inventors: Sumio Kamiya, Tatsuo Shou, Yukinobu Kato, Noboru Otake, Harumi Kimura, Kazumichi Yanagisawa, Nan Li, Wuxing Zhang
  • Publication number: 20150249812
    Abstract: In a stereoscopic image processing device, disparity distribution of a stereoscopic image can be adaptively transformed in accordance with visual characteristics of a person relating to stereoscopic vision. The stereoscopic image processing device includes a disparity distribution transformation section (30) that transforms disparity distribution of a stereoscopic image input by an input section (10). The disparity distribution transformation section (30) reduces a difference in disparity between adjacent pixels in an area of the stereoscopic image, in which the difference in disparity between the adjacent pixels is large.
    Type: Application
    Filed: August 30, 2013
    Publication date: September 3, 2015
    Applicant: Kochi University of Technology
    Inventors: Ikuko Tsubaki, Mikio Seto, Hisao Kumai, Hiroaki Shigemasu
  • Publication number: 20150210731
    Abstract: The objective of the present invention is to provide a monomer for RNA synthesis which can be efficiently produced and therefore by which the producing cost of RNA can be remarkably decreased, and a method for efficiently producing the monomer in a small number of steps. In addition, the objective of the present invention is also to provide a method by which RNA can be efficiently produced even when a approximately stoichiometry amount of the monomer for RNA synthesis is used. The monomer for RNA synthesis according to the present invention is represented by the following formula (I) or (I?): wherein R1 is a protective group of the hydroxy group and R2 is an alkyl group or the like.
    Type: Application
    Filed: July 25, 2013
    Publication date: July 30, 2015
    Applicant: Kochi University
    Inventor: Masanori Kataoka
  • Patent number: 9045556
    Abstract: The present invention provides an adjuvant for cancer antigen peptide vaccines and virus antigen peptides, containing a pertussis vaccine as a primary ingredient. The present invention also provides a therapeutic agent for a cancer or viral infectious disease, and a prophylactic agent for metastasis or recurrence of cancer or onset of virus-induced tumor, containing a cancer antigen peptide or virus antigen peptide and a pertussis vaccine. A pertussis vaccine that can be suitably used is a whole cell body pertussis vaccine. The agents of the present invention can be safely administered in a plurality of doses.
    Type: Grant
    Filed: February 7, 2008
    Date of Patent: June 2, 2015
    Assignees: NEC Corporation, The Research Foundation for Microbial Disease of Osaka University, National University Corporation Kochi University
    Inventors: Keiko Udaka, Masahide Ishibashi
  • Patent number: 9045531
    Abstract: An HLA-binding peptide binding to an HLA-A type molecule is provided that includes one or more types of amino acid sequence selected from the group consisting of SEQ ID NOS: 1 to 52, and not less than 8 and not more than 11 amino acid residues. All of these amino acid sequences are amino acid sequences predicted to bind to a human HLA-A molecule using a prediction program employing an active learning experiment method shown in FIG. 1.
    Type: Grant
    Filed: November 16, 2010
    Date of Patent: June 2, 2015
    Assignees: NEC CORPORATION, Kochi University
    Inventors: Tomoya Miyakawa, Keiko Udaka
  • Publication number: 20150148665
    Abstract: [Problem] To accurately check a usage status of a medical product such as a damage status of the medical product or existence or nonexistence of the medical product. [Solution] A medical product (80) is configured to include a light-emissive septum (83) (constituent member) which includes a luminescent agent emitting near-infrared fluorescence according to irradiation of excitation light on a surface thereof. Even in a case where a port ion of the septum is separated as a core (83a) (separate piece) due to damage, the luminescent agent is also included on a surface of the core.
    Type: Application
    Filed: May 28, 2013
    Publication date: May 28, 2015
    Applicant: National University Corporation Kochi University
    Inventor: Takayuki Sato
  • Patent number: 8999877
    Abstract: This invention provides a fine particle composite comprising fine powder of a sulfide or sulfide complex comprising a given element. The fine particle composite is obtained by a method for producing a fine particle composite comprising fine powder of a sulfide or sulfide complex comprising at least one element selected from the group consisting of molybdenum (Mo), rhodium (Rh), ruthenium (Ru), and rhenium (Re). Such method comprises steps of: preparing a solvent mixture from at least one compound containing an element selected from among molybdenum (Mo), rhodium (Rh), ruthenium (Ru), rhenium (Re), and sulfur (S); and subjecting the solvent mixture to a hydrothermal or solvothermal reaction. The resulting fine particle composite comprises fine particles of a sulfide or sulfide complex comprising at least one element selected from the group consisting of molybdenum (Mo), rhodium (Rh), ruthenium (Ru), and rhenium (Re).
    Type: Grant
    Filed: September 12, 2008
    Date of Patent: April 7, 2015
    Assignees: Toyota Jidosha Kabushiki Kaisha, National University Corporation Kochi University
    Inventors: Sumio Kamiya, Tatsuo Shou, Yukinobu Kato, Noboru Otake, Kazumichi Yanagisawa, Wuxing Zhang