Patents Assigned to Kochi University
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Publication number: 20240026308Abstract: The objective of the present invention is to provide a novel bacteriophage useful for treating bacterial endophthalmitis and a therapeutic agent for bacterial endophthalmitis comprising the novel bacteriophage. The therapeutic agent for bacterial endophthalmitis according to the present invention is characterized in comprising 1 or more bacteriophages selected from the group essentially consisting of Myoviridae Spounavirinae phiEF7H (accession number: NITE BP-02886), Myoviridae Spounavirinae phiEF19G (accession number: NITE BP-02887), Myoviridae Spounavirinae phiEF14H1 (accession number: NITE BP-02888), and mutants thereof.Type: ApplicationFiled: September 8, 2023Publication date: January 25, 2024Applicant: National University Corporation Kochi UniversityInventors: Ken FUKUDA, Shigenobu MATSUZAKI, Atsuki FUKUSHIMA, Masanori DAIBATA, Jumpei UCHIYAMA
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Patent number: 11304658Abstract: The method for diagnosing cerebrospinal fluid hypovolemia includes injecting saline into a subdural space of a subject in a decubitus position, raising an upper body of the subject, and then determining whether the subject has headache or not, or headache of the subject is relieved or not.Type: GrantFiled: August 9, 2019Date of Patent: April 19, 2022Assignee: National University Corporation Kochi UniversityInventors: Eiichi Nakai, Tetsuya Ueba
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Patent number: 10349886Abstract: [Problem] To provide an artery visualization device capable of very appropriately visualizing a to-be-punctured artery and an artery imaging device used for the artery visualization device.Type: GrantFiled: May 28, 2013Date of Patent: July 16, 2019Assignee: National University Corporation Kochi UniversityInventors: Takayuki Sato, Tatsumi Ike
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Patent number: 10174111Abstract: According to the present disclosure there are provided compositions and methods for treating malignant tumors, including an anti-LSR (lipolysis stimulated lipoprotein receptor) antibody that comprises the presently disclosed antibody heavy and light chain complementarity determining region (CDR) sequences, or an antigen-binding fragment thereof, or a functional equivalent thereof. Further provided for treating an LSR-positive malignancy is an LSR antagonist or an LSR inhibitor such as a nucleic acid. Therapeutic administration of the anti-LSR antibody to a subject having an LSR-positive malignant tumor is also described.Type: GrantFiled: December 25, 2014Date of Patent: January 8, 2019Assignee: National University Corporation Kochi UniversityInventors: Tetsuji Naka, Satoshi Serada, Minoru Fujimoto, Masayoshi Toyoura, Yuji Shoya
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Patent number: 10077316Abstract: The present invention relates to an esophageal cancer marker and application thereof. The present invention relates to: a marker that includes Glypican-1 or an expression product thereof, or a fragment or derivative thereof, and serves to identify esophageal cancer; a detection agent that includes a substance that binds to Glypican-1 or an expression product thereof; and a composition that includes a Glypican-1 inhibitor and serves to prevent or treat esophageal cancer. Herein, Glypican-1 can be SEQ ID NO: 1 (nucleic acid sequence) or SEQ ID NO: 2 (amino acid sequence), or an equivalent thereof.Type: GrantFiled: December 25, 2014Date of Patent: September 18, 2018Assignee: National University Corporation, Kochi UniversityInventors: Tetsuji Naka, Satoshi Serada, Minoru Fujimoto, Masayoshi Toyoura, Yuji Shoya
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Patent number: 10058847Abstract: A titanium-oxide catalyst containing catalytic metal shows catalysis under high temperature conditions. A titanium-oxide catalyst contains a titanium-oxide nanoparticle assembly and ruthenium particles. The titanium-oxide nanoparticle assembly is an assembly of titanium-oxide nanoparticles, which are nanoparticles of titanium oxide. The ruthenium particles have a smaller particle diameter than the titanium-oxide nanoparticle assembly and the titanium-oxide nanoparticles. The ruthenium particles are dispersed and supported on a surface of the titanium-oxide nanoparticle assembly.Type: GrantFiled: March 17, 2016Date of Patent: August 28, 2018Assignees: Nippon Pillar Packing Co., Ltd., Kochi University of TechnologyInventors: Kazuya Kobiro, Masataka Otani, Keiichiro Moriwaki, Yukimi Hayashi
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Patent number: 10010872Abstract: A titanium-oxide catalyst containing catalytic metal shows catalysis under high temperature conditions. A titanium-oxide catalyst contains a titanium-oxide nanoparticle assembly and ruthenium particles. The titanium-oxide nanoparticle assembly is an assembly of titanium-oxide nanoparticles, which are nanoparticles of titanium oxide. The ruthenium particles have a smaller particle diameter than the titanium-oxide nanoparticle assembly and the titanium-oxide nanoparticles. The ruthenium particles are dispersed and supported on a surface of the titanium-oxide nanoparticle assembly.Type: GrantFiled: March 17, 2016Date of Patent: July 3, 2018Assignees: Nippon Pillar Packing Co., Ltd., Kochi University of TechnologyInventors: Kazuya Kobiro, Masataka Otani, Keiichiro Moriwaki, Yukimi Hayashi
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Patent number: 9900484Abstract: A method includes the steps of emitting infrared light of a predetermined wavelength to an object, receiving infrared light of a predetermined wavelength different from the infrared light emitted from the object, and adjusting white balance of an image output from a camera at this time, thereby showing the incident infrared light as white. The method further includes the steps of emitting white visible light to the object from an RGB light source, receiving visible light emitted from the object, and adjusting the intensity of the RGB light source for each of R, G, and B, thereby adjusting white balance of a captured image.Type: GrantFiled: July 22, 2011Date of Patent: February 20, 2018Assignees: Semiconductor Components Industries, LLC, National University Corporation Kochi UniversityInventors: Kazuaki Kojima, Takashi Tanimoto, Takayuki Sato
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Publication number: 20170362737Abstract: A method of producing an apatite crystal includes the steps of preparing an apatite single crystal expressed by the general formula M25(PO4)3X (M2 being at least atomic element selected from the group consisting of divalent alkaline-earth metals and Eu, and X is at least one atomic selected from the group consisting of halogens); placing the apatite single crystal into a space controllable to a predetermined atmosphere; supplying water vapor into the space; and heating such that the atmosphere in the space is within a 1000° C. to 1400° C. range.Type: ApplicationFiled: June 14, 2017Publication date: December 21, 2017Applicants: Koito Manufacturing Co., Ltd., Kochi UniversityInventors: Yu SHINOMIYA, Kazumichi YANAGISAWA, Masoud Sakaki
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Patent number: 9772286Abstract: It is to provide a method for detecting urothelial cancer simply and with high accuracy. It is a method for detecting urothelial cancer comprising administering 5-aminolevulinic acid (ALA), a derivative thereof, or a salt of these to a test subject, collecting urine from the test subject, and detecting the presence of fluorescence or amount of fluorescence in the collected urine.Type: GrantFiled: June 20, 2011Date of Patent: September 26, 2017Assignees: SBI Pharmaceuticals Co., Ltd., National University Corporation Kochi UniversityInventors: Keiji Inoue, Taro Shuin, Mutsuo Furihata, Yoshihiko Hirao, Tohru Tanaka
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Patent number: 9707196Abstract: A method for treating side effects of anticancer agent includes administering to a subject in need thereof a prophylactic and/or therapeutic agent containing a therapeutically effective amount of a compound shown by the following Formula (I): R1—NHCH2COCH2CH2COOR2??(I) wherein R1 represents a hydrogen atom or an acyl group, and R2 represents a hydrogen atom, a linear or branched alkyl group, a cycloalkyl group, an aryl group, or an aralkyl group, or a salt thereof.Type: GrantFiled: October 5, 2012Date of Patent: July 18, 2017Assignees: SBI Pharmaceuticals Co., Ltd., National University Corporation Kochi UniversityInventors: Tohru Tanaka, Kyoko Tsuchiya, Masahiro Ishizuka, Motowo Nakajima, Hitoshi Nakagawa, Taro Shuin, Keiji Inoue, Hideo Fukuhara, Masayuki Tsuda, Mutsuo Furihata
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Patent number: 9363196Abstract: The present invention is provided with: a data-driven processor comprising at least a firing control which determines whether or not firing conditions have been met by determining whether or not all packets necessary for instruction execution have been received when a packet that convey a part of partitioned data to be processed has been input, and a data processing unit for performing processing corresponding to the packets transmitted from the firing control if the firing conditions have been met; a power supply circuit for supplying power to the data-driven processor; and overload avoidance means for refusing input of the packets to the data-driven processor, if a determination has been made that a data processing load in the data-driven processor may reach an overloaded state in which the data processing may stall, on the basis of current consumption in the data-driven processor. Accordingly, power consumption in a networking system is reduced.Type: GrantFiled: July 9, 2012Date of Patent: June 7, 2016Assignees: University of Tsukuba, Kochi University of Technology, Tokai UniversityInventors: Hiroaki Nishikawa, Shuji Sannomiya, Makoto Iwata, Hiroshi Ishii, Keisuke Utsu
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Patent number: 9303056Abstract: The objective of the present invention is to provide a monomer for RNA synthesis which can be efficiently produced and therefore by which the producing cost of RNA can be remarkably decreased, and a method for efficiently producing the monomer in a small number of steps. In addition, the objective of the present invention is also to provide a method by which RNA can be efficiently produced even when a approximately stoichiometry amount of the monomer for RNA synthesis is used. The monomer for RNA synthesis according to the present invention is represented by the following formula (I) or (I?): wherein R1 is a protective group of the hydroxy group and R2 is an alkyl group or the like.Type: GrantFiled: July 25, 2013Date of Patent: April 5, 2016Assignee: Kochi UniversityInventor: Masanori Kataoka
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Patent number: 9193604Abstract: This invention provides a fine particle composite comprising fine particles of a sulfide or sulfide complex comprising at least one element selected from the group consisting of molybdenum (Mo), rhodium (Rh), ruthenium (Ru), and rhenium (Re) and conductive fine particles via a step of preparing a solvent mixture from a compound containing conductive carbon powder, at least one compound containing an element selected from among molybdenum (Mo), rhodium (Rh), ruthenium (R), and rhenium (Re), and sulfur (S) and a step of conducting a hydrothermal or solvothermal reaction at a pressure and temperature that convert the solvent mixture into a supercritical or subcritical water or solvent.Type: GrantFiled: September 12, 2008Date of Patent: November 24, 2015Assignees: Toyota Jidosha Kabushiki Kaisha, National University Corporation Kochi UniversityInventors: Sumio Kamiya, Tatsuo Shou, Yukinobu Kato, Noboru Otake, Harumi Kimura, Kazumichi Yanagisawa, Nan Li, Wuxing Zhang
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Publication number: 20150249812Abstract: In a stereoscopic image processing device, disparity distribution of a stereoscopic image can be adaptively transformed in accordance with visual characteristics of a person relating to stereoscopic vision. The stereoscopic image processing device includes a disparity distribution transformation section (30) that transforms disparity distribution of a stereoscopic image input by an input section (10). The disparity distribution transformation section (30) reduces a difference in disparity between adjacent pixels in an area of the stereoscopic image, in which the difference in disparity between the adjacent pixels is large.Type: ApplicationFiled: August 30, 2013Publication date: September 3, 2015Applicant: Kochi University of TechnologyInventors: Ikuko Tsubaki, Mikio Seto, Hisao Kumai, Hiroaki Shigemasu
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Publication number: 20150210731Abstract: The objective of the present invention is to provide a monomer for RNA synthesis which can be efficiently produced and therefore by which the producing cost of RNA can be remarkably decreased, and a method for efficiently producing the monomer in a small number of steps. In addition, the objective of the present invention is also to provide a method by which RNA can be efficiently produced even when a approximately stoichiometry amount of the monomer for RNA synthesis is used. The monomer for RNA synthesis according to the present invention is represented by the following formula (I) or (I?): wherein R1 is a protective group of the hydroxy group and R2 is an alkyl group or the like.Type: ApplicationFiled: July 25, 2013Publication date: July 30, 2015Applicant: Kochi UniversityInventor: Masanori Kataoka
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Patent number: 9045556Abstract: The present invention provides an adjuvant for cancer antigen peptide vaccines and virus antigen peptides, containing a pertussis vaccine as a primary ingredient. The present invention also provides a therapeutic agent for a cancer or viral infectious disease, and a prophylactic agent for metastasis or recurrence of cancer or onset of virus-induced tumor, containing a cancer antigen peptide or virus antigen peptide and a pertussis vaccine. A pertussis vaccine that can be suitably used is a whole cell body pertussis vaccine. The agents of the present invention can be safely administered in a plurality of doses.Type: GrantFiled: February 7, 2008Date of Patent: June 2, 2015Assignees: NEC Corporation, The Research Foundation for Microbial Disease of Osaka University, National University Corporation Kochi UniversityInventors: Keiko Udaka, Masahide Ishibashi
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Patent number: 9045531Abstract: An HLA-binding peptide binding to an HLA-A type molecule is provided that includes one or more types of amino acid sequence selected from the group consisting of SEQ ID NOS: 1 to 52, and not less than 8 and not more than 11 amino acid residues. All of these amino acid sequences are amino acid sequences predicted to bind to a human HLA-A molecule using a prediction program employing an active learning experiment method shown in FIG. 1.Type: GrantFiled: November 16, 2010Date of Patent: June 2, 2015Assignees: NEC CORPORATION, Kochi UniversityInventors: Tomoya Miyakawa, Keiko Udaka
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Publication number: 20150148665Abstract: [Problem] To accurately check a usage status of a medical product such as a damage status of the medical product or existence or nonexistence of the medical product. [Solution] A medical product (80) is configured to include a light-emissive septum (83) (constituent member) which includes a luminescent agent emitting near-infrared fluorescence according to irradiation of excitation light on a surface thereof. Even in a case where a port ion of the septum is separated as a core (83a) (separate piece) due to damage, the luminescent agent is also included on a surface of the core.Type: ApplicationFiled: May 28, 2013Publication date: May 28, 2015Applicant: National University Corporation Kochi UniversityInventor: Takayuki Sato
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Patent number: 8999877Abstract: This invention provides a fine particle composite comprising fine powder of a sulfide or sulfide complex comprising a given element. The fine particle composite is obtained by a method for producing a fine particle composite comprising fine powder of a sulfide or sulfide complex comprising at least one element selected from the group consisting of molybdenum (Mo), rhodium (Rh), ruthenium (Ru), and rhenium (Re). Such method comprises steps of: preparing a solvent mixture from at least one compound containing an element selected from among molybdenum (Mo), rhodium (Rh), ruthenium (Ru), rhenium (Re), and sulfur (S); and subjecting the solvent mixture to a hydrothermal or solvothermal reaction. The resulting fine particle composite comprises fine particles of a sulfide or sulfide complex comprising at least one element selected from the group consisting of molybdenum (Mo), rhodium (Rh), ruthenium (Ru), and rhenium (Re).Type: GrantFiled: September 12, 2008Date of Patent: April 7, 2015Assignees: Toyota Jidosha Kabushiki Kaisha, National University Corporation Kochi UniversityInventors: Sumio Kamiya, Tatsuo Shou, Yukinobu Kato, Noboru Otake, Kazumichi Yanagisawa, Wuxing Zhang